Results 61 to 70 of about 11,764 (212)

Structure of the dimeric form of CTP synthase from Sulfolobus solfataricus [PDF]

open access: yes, 2011
CTP synthase catalyzes the last committed step in de novo pyrimidine-nucleotide biosynthesis. Active CTP synthase is a tetrameric enzyme composed of a dimer of dimers.
Harris, Pernille   +4 more
core   +1 more source

Merging Biocatalysis and Chemocatalysis in Flow: State‐of‐the‐Art and Future Directions for Sustainable Synthesis

open access: yesAngewandte Chemie International Edition, EarlyView.
This review highlights recent advances in integrating biocatalysis and chemocatalysis in continuous flow to create streamlined, sustainable processes. It examines chemo‐enzymatic cascades combining at least one enzymatic and one chemical step, discusses challenges such as enzyme immobilization, leaching, and reactor clogging, and presents solutions ...
Petros Siasiaridis   +2 more
wiley   +1 more source

Protein acetylation in archaea, bacteria, and eukaryotes [PDF]

open access: yes, 2010
Proteins can be acetylated at the alpha-amino group of the N-terminal amino acid (methionine or the penultimate amino acid after methionine removal) or at the epsilon-amino group of internal lysines.
Lainio, Jarmo   +1 more
core   +1 more source

The Role of Polyphosphate in Motility, Adhesion, and Biofilm Formation in Sulfolobales

open access: yesMicroorganisms, 2021
Polyphosphates (polyP) are polymers of orthophosphate residues linked by high-energy phosphoanhydride bonds that are important in all domains of life and function in many different processes, including biofilm development. To study the effect of polyP in
Alejandra Recalde   +5 more
doaj   +1 more source

The genome-scale DNA-binding profile of BarR, a β-alanine responsive transcription factor in the archaeon Sulfolobus acidocaldarius [PDF]

open access: yes, 2016
The DNA-binding domains of S. acidocaldarius BarR and S. solfataricus Ss-LrpB might share a common ancestor.
Ann-Christin Lindås   +3 more
core   +2 more sources

Snapshots of Motion: A Novel Structural Intermediate Reveals Conserved Dynamics in Archaeal DNA Ligases

open access: yesProteins: Structure, Function, and Bioinformatics, Volume 94, Issue 6, Page 1245-1258, June 2026.
ABSTRACT We present the first x‐ray crystallographic structural evidence of an archaeal DNA ligase showing the AMP covalent adduct together with further cofactor hydrolysis, capturing a transient intermediary in the first step of the ligation reaction, triggered by the pyrophosphate hydrolysis.
A. X. Quintana‐Armas   +3 more
wiley   +1 more source

Efficient CRISPR-Mediated Post-Transcriptional Gene Silencing in a Hyperthermophilic Archaeon Using Multiplexed crRNA Expression

open access: yesG3: Genes, Genomes, Genetics, 2016
CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)-mediated RNA degradation is catalyzed by a type III system in the hyperthermophilic archaeon Sulfolobus solfataricus. Earlier work demonstrated that the system can be engineered to target
Ziga Zebec   +3 more
doaj   +1 more source

Display of the peroxiredoxin Bcp1 of Sulfolobus solfataricus on probiotic spores of Bacillus megaterium. [PDF]

open access: yes, 2018
Bacterial spores displaying heterologous proteins have been proposed as a safe and efficient method for delivery of antigens and enzymes to animal mucosal surfaces.
Donadio, Giuliana   +6 more
core   +1 more source

Molecular analysis of 3D domain swapping in the acylphosphatase from Escherichia coli

open access: yesActa Crystallographica Section D, Volume 82, Issue 4, Page 336-347, April 2026.
Structures of the monomer and intertwined dimer of the acylphosphatase from E. coli shed light on the molecular basis of its 3D domain swapping.Three‐dimensional domain swapping is a mechanism by which proteins form oligomers. At present, the molecular basis that dictates whether some proteins fold in their monomeric form or as intertwined oligomers is
Sergio Martínez-Rodríguez   +4 more
wiley   +1 more source

Diversity of DNA replication in the archaea [PDF]

open access: yes, 2017
DNA replication is arguably the most fundamental biological process. On account of their shared evolutionary ancestry, the replication machinery found in archaea is similar to that found in eukaryotes.
Akita   +6 more
core   +3 more sources

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