Results 51 to 60 of about 24,088 (253)
The cell cycle of Sulfolobus [PDF]
Molecular Microbiology, 2007 SummaryMuch of the current information about the archaeal cell cycle has been generated through studies of the genus Sulfolobus. The overall organization of the cell cycle in these species is well understood, and information about the regulatory principles that govern cell cycle progression is rapidly accumulating.
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Appendage-Mediated Surface Adherence of Sulfolobus solfataricus [PDF]
Journal of Bacteriology, 2010 ABSTRACT Attachment of microorganisms to surfaces is a prerequisite for colonization and biofilm formation. The hyperthermophilic crenarchaeote Sulfolobus solfataricus was able to attach to a variety of surfaces, such as glass, mica, pyrite, and carbon-coated gold grids.
Zolghadr, Behnam +5 more
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Hydroxyurea-Mediated Cytotoxicity Without Inhibition of Ribonucleotide Reductase
Cell Reports, 2016 In many organisms, hydroxyurea (HU) inhibits class I ribonucleotide reductase, leading to lowered cellular pools of deoxyribonucleoside triphosphates. The reduced levels for DNA precursors is believed to cause replication fork stalling. Upon treatment of
Li Phing Liew +6 more
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Dimer-dimer stacking interactions are important for nucleic acid binding by the archaeal chromatin protein Alba [PDF]
, 2013 Archaea use a variety of small basic proteins to package their DNA. One of the most widespread and highly conserved is the Alba (Sso10b) protein. Alba interacts with both DNA and RNA in vitro, and we show in the present study that it binds more tightly ...
Ingledew, W John +3 more
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Structural basis of RNA polymerase inhibition by viral and host factors
Nature Communications, 2021 Understanding the structural basis for the inhibition of archaeal eukaryotic-like RNA polymerases (RNAPs) during virus infection is of interest for drug design.
Simona Pilotto +9 more
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Optimization of Enzymatic Gas-Phase Reactions by Increasing the Long-Term Stability of the Catalyst [PDF]
, 2004 Enzymatic gas-phase reactions are usually performed in continuous reactors, and thus very stable and active catalysts are required to perform such transformations on cost-effective levels.
Büchs, Jochen, +4 more
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Beyond PEGylation: Archaeal Lipids for Long‐Circulating Liposomes
Advanced NanoBiomed Research, EarlyView.Archaeal lipid‐based liposomes, particularly those containing caldarchaeol (GDGT), were found to significantly prolong the circulation time of vancomycin in rats, matching the pharmacokinetic properties of PEGylated systems. These findings suggest archaeal lipids as promising non‐PEG excipients for parenteral applications to minimize drug clearance ...
Viktor Sedlmayr +9 more
wiley +1 more source
Frontiers in Microbiology, 2021 Sulfolobaceae family, comprising diverse thermoacidophilic and aerobic sulfur-metabolizing Archaea from various geographical locations, offers an ideal opportunity to infer the evolutionary dynamics across the members of this family.
Rachana Banerjee +13 more
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Rings in the Extreme: PCNA Interactions and Adaptations in the Archaea [PDF]
, 2012 Biochemical and structural analysis of archaeal proteins has enabled us to gain great insight into many eukaryotic processes, simultaneously offering fascinating glimpses into the adaptation and evolution of proteins at the extremes of life. The archaeal
Bunting, KA, Winter, JA
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Asymmetric Reduction of Unactivated Alkenes
Chemistry – A European Journal, EarlyView.Unactivated alkenes rank among the most inert functional groups in synthesis and their selective reduction remains challenging. This Review charts the evolution from classical metal‐catalyzed hydrogenation to radical hydrogen atom transfer (HAT) and emerging biocatalytic concepts, highlighting how complementary mechanistic strategies, including the ...
Nico D. Fessner +3 more
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