An HflX-type GTPase from Sulfolobus solfataricus binds to the 50S ribosomal subunit in all nucleotide-bound states [PDF]
, 2011 HflX GTPases are found in all three domains of life, Bacteria, Archaea, and Eukaryotes. HflX from Escherichia coli has been shown to bind to the 50S ribosomal subunit in a nucleotide-dependent manner and this interaction strongly stimulates its GTPase ...
Fabian Blombach +27 more
core +1 more source
Growth Phase-Dependent Gene Regulation in Vivo in Sulfolobus Solfataricus [PDF]
, 2011 Ribosomal genes are strongly regulated dependent on growth phase in all organisms, but this regulation is poorly understood in Archaea. Moreover, very little is known about growth phase-dependent gene regulation in Archaea. SSV1- based lacS reporter gene
DeYoung, Melissa +7 more
core +3 more sources
"Hot standards" for the thermoacidophilic archaeon Sulfolobus solfataricus [PDF]
, 2009 Within the archaea, the thermoacidophilic crenarchaeote Sulfolobus solfataricus has become an important model organism for physiology and biochemistry, comparative and functional genomics, as well as, more recently also for systems biology approaches ...
Gertig, Susanne +78 more
core +1 more source
Prediction of mutations on structure primase of the archaeon Sulfolobus solfataricus
Acta Scientiarum: Biological Sciences, 2017 All living organisms need a DNA replication mechanism and it has been conserved in the three domains of life throughout evolutionary process. Primase is the enzyme responsible for synthesizing de novo RNA primers in DNA replication. Archaeo-Eukaryotic
Eden Silva e Souza +1 more
doaj +1 more source
Biological Membranes in Extreme Conditions: Simulations of Anionic Archaeal Tetraether Lipid Membranes. [PDF]
PLoS ONE, 2016 In contrast to the majority of organisms that have cells bound by di-ester phospholipids, archaeal membranes consist of di- and tetraether phospholipids.
Luis Felipe Pineda De Castro +2 more
doaj +1 more source
Life, 2015 Plasmids occur frequently in Archaea. A novel plasmid (denoted pTC1) containing typical conjugation functions has been isolated from Sulfolobus tengchongensis RT8-4, a strain obtained from a hot spring in Tengchong, China, and characterized.
Xiaoyu Xiang +3 more
doaj +1 more source
Extensive lysine methylation in hyperthermophilic crenarchaea : potential implications for protein stability and recombinant enzymes [PDF]
, 2010 In eukarya and bacteria, lysine methylation is relatively rare and is catalysed by sequence-specific lysine methyltransferases that typically have only a single-protein target.
Botting, Catherine H. +8 more
core +1 more source
Hydroxyurea-Mediated Cytotoxicity Without Inhibition of Ribonucleotide Reductase
Cell Reports, 2016 In many organisms, hydroxyurea (HU) inhibits class I ribonucleotide reductase, leading to lowered cellular pools of deoxyribonucleoside triphosphates. The reduced levels for DNA precursors is believed to cause replication fork stalling. Upon treatment of
Li Phing Liew +6 more
doaj +1 more source
The Mre11 protein interacts with both Rad50 and the HerA bipolar helicase and is recruited to DNA following gamma irradiation in the archaeon Sulfolobus acidocaldarius [PDF]
, 2008 Background: The ubiquitous Rad50 and Mre11 proteins play a key role in many processes involved in the maintenance of genome integrity in Bacteria and Eucarya, but their function in the Archaea is presently unknown.
Patrick Forterre +11 more
core +1 more source
Structural basis of RNA polymerase inhibition by viral and host factors
Nature Communications, 2021 Understanding the structural basis for the inhibition of archaeal eukaryotic-like RNA polymerases (RNAPs) during virus infection is of interest for drug design.
Simona Pilotto +9 more
doaj +1 more source