Results 21 to 30 of about 14,486 (168)

Hot and crispy : CRISPR-Cas systems in the hyperthermophile Sulfolobus solfataricus [PDF]

open access: yes, 2013
The CRISPR (clustered regularly interspaced short palindromic repeats) and Cas (CRISPR-associated) genes are widely spread in bacteria and archaea, representing an intracellular defence system against invading viruses and plasmids.
Zhang, Jing   +2 more
core   +1 more source

Characterisation of Sulfolobus solfataricus Ard1, a promiscuous N-acetyltransferase [PDF]

open access: yes, 2008
Compaction of DNA into chromatin is an important feature of every living cell. This compaction phenomenon is brought about and maintained by a variety of DNA binding proteins, which have evolved to suit the specific needs of the different cell types ...
Mackay, Dale Tara
core   +2 more sources

Killer Archaea: Virus-Mediated Antagonism to CRISPR-Immune Populations Results in Emergent Virus-Host Mutualism

open access: yesmBio, 2020
Theory, simulation, and experimental evolution demonstrate that diversified CRISPR-Cas immunity to lytic viruses can lead to stochastic virus extinction due to a limited number of susceptible hosts available to each potential new protospacer escape ...
Samantha J. DeWerff   +4 more
doaj   +1 more source

Responses of hyperthermophilic crenarchaea to UV irradiation [PDF]

open access: yes, 2007
This work was supported by a dedicated functional genomics grant from the Swedish Research Council and the Swedish Graduate Research School in Genomics and Bioinformatics to RB, and by grants from the Wellcome Trust and BBSRC to MFW.Background: DNA ...
Lundgren, Magnus,   +15 more
core   +1 more source

Sulfolobus – A Potential Key Organism in Future Biotechnology

open access: yesFrontiers in Microbiology, 2017
Extremophilic organisms represent a potentially valuable resource for the development of novel bioprocesses. They can act as a source for stable enzymes and unique biomaterials.
Julian Quehenberger   +4 more
doaj   +1 more source

Improving low-temperature activity of Sulfolobus acidocaldarius 2-keto-3-deoxygluconate aldolase [PDF]

open access: yes, 2009
Sulfolobus acidocaldarius 2-keto-3-deoxygluconate aldolase (SacKdgA) displays optimal activity at 95 degrees C and is studied as a model enzyme for aldol condensation reactions.
Siemerink, M.A.J.   +5 more
core   +1 more source

Replication-biased genome organisation in the crenarchaeon Sulfolobus

open access: yesBMC Genomics, 2010
Background Species of the crenarchaeon Sulfolobus harbour three replication origins in their single circular chromosome that are synchronously initiated during replication.
Lundgren Magnus   +5 more
doaj   +1 more source

Electron cryo-microscopy reveals the structure of the archaeal thread filament

open access: yesNature Communications, 2022
Pili are filamentous appendages on the surface of bacteria and archaea, and play roles in multiple processes such as adhesion, motility and horizontal gene transfer. Here, Gaines et al. describe the structure of a new type of pilus, termed ‘thread’, from
Matthew C. Gaines   +10 more
doaj   +1 more source

Genetic engineering of sulfur-degrading Sulfolobus [PDF]

open access: yes, 1991
The objectives of the proposed research is to first establish a plasmid-mediated genetic transformation system for the sulfur degrading Sulfolobus, and then to clone and overexpress the genes encoding the organic-sulfur-degrading enzymes from Sulfolobus-
Ho, N.W.Y.
core   +1 more source

Structural conservation in a membrane-enveloped filamentous virus infecting a hyperthermophilic acidophile

open access: yesNature Communications, 2018
Only a few archaeal filamentous viruses have been structurally characterized. Here the authors describe the membrane-enveloped Sulfolobus filamentous virus 1 that infects Sulfolobus shibatae and present its 3.7 Å resolution cryo-EM structure, which ...
Ying Liu   +7 more
doaj   +1 more source

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