Results 81 to 90 of about 77,925 (335)

Bridged [2.2.1] bicyclic phosphine oxide facilitates catalytic γ-umpolung addition-Wittig olefination. [PDF]

, 2018
A novel bridged [2.2.1] bicyclic phosphine oxide, devised to circumvent the waste generation and burdens of purification that are typical of reactions driven by the generation of phosphine oxides, has been prepared in three steps from commercially ...
Cai, Lingchao, Houk, KN, Kwon, Ohyun, Yang, Zhongyue, Zhang, Kui   +4 more
core   +1 more source

N-(1-Allyl-1H-indazol-5-yl)-4-methoxybenzenesulfonamide hemihydrate

Acta Crystallographica Section E, 2013
In the title compound, C17H17N3O3.0.5H2O, the indazole system makes a dihedral angle of 46.19 (8)° with the plane through the benzene ring and is nearly perpendicular to the allyl group, as indicated by the dihedral angle of 81.2 (3 ...
Hakima Chicha, El Mostapha Rakib, Detlef Geffken, Mohamed Saadi, Lahcen El Ammari   +4 more
doaj   +1 more source

(E)-4-Amino-N-(1,2-dihydropyridin-2-ylidene)benzenesulfonamide nitromethane monosolvate

Acta Crystallographica Section E, 2012
In the title solvate, C11H11N3O2S·CH3NO2, the dihedral angle between the benzene ring and the N-containing ring is 85.94 (11)°, and an approximate V shape arises for the sulfonamide molecule.
Mostafa M. Ghorab, Mansour S. Al-Said, Hazem A. Ghabbour, Suchada Chantrapromma, Hoong-Kun Fun   +4 more
doaj   +1 more source

Identification of Small-Molecule Inhibitors against Meso-2, 6-Diaminopimelate Dehydrogenase from Porphyromonas gingivalis [PDF]

, 2015
Species-specific antimicrobial therapy has the potential to combat the increasing threat of antibiotic resistance and alteration of the human microbiome.
Chen, Weihau, El-rami, Fadi, Ge, Xiuchun, Kellogg, Glen E., Parikh, Hardik I., Stone, Victoria N, Xu, Ping, Zhang, Yan   +7 more
core   +5 more sources

Identification and synthesis of metabolites of the new antiglaucoma drug

Research Results in Pharmacology
Introduction: The determination of biotransformation products is an essential part of the preclinical trial of original medicines. These studies have not been conducted before for the new drug 5-[5-(trifluoromethyl)-1,2-oxazole-3-yl]-furan-2-sulfonamide.
Alexander L. Khokhlov, Ilya I. Yaichkov, Anton А. Shetnev, Sergey A. Ivanovsky, Mikhail K. Korsakov, Mikhail A. Alexeev, Olga A. Gasilina, Nikita N. Volkhin, Sergey S. Petukhov   +8 more
doaj   +1 more source

Crystal structure of 5,5′-bis(dimethylamino)-N,N′-(3-methyl-3-azapentane-1,5-diyl)di(naphthalene-1-sulfonamide)

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C29H37N5O4S2, two arms substituted with dansyl derivatives are connected to a central tertiary amine, where the dihedral angle between the planes of two dansyl units is 56.39 (4)°.
Toyketa V. Horne, Syed A. Haque, Adrianne Barton, Md. Alamgir Hossain   +3 more
doaj   +1 more source

Identification of novel 2-benzoxazolinone derivatives with specific inhibitory activity against the HIV-1 nucleocapsid protein [PDF]

, 2018
In this report, we present a new benzoxazole derivative endowed with inhibitory activity against the HIV-1 nucleocapsid protein (NC). NC is a 55-residue basic protein with nucleic acid chaperone properties, which has emerged as a novel and potential ...
Botta, Maurizio, Fabris, Dan, Gamba, Elia, Gatto, Barbara, Giannini, Alessia, Kovalenko, Lesia, Mely, YVES CAMILLE RENE', Mori, Mattia, Saladini, Francesco, Sosic, Alice   +9 more
core   +2 more sources

Identification of dfrA14 in two distinct plasmids conferring trimethoprim resistance in Actinobacillus pleuropneumoniae [PDF]

, 2015
OBJECTIVES: The objective of this study was to determine the distribution and genetic basis of trimethoprim resistance in Actinobacillus pleuropneumoniae isolates from pigs in England.
Alexander W. Tucker, Andrew N. Rycroft, Brendan W. Wren, Clinical and Laboratory Standards Institute, de Groot, Duncan J. Maskell, Janine T. Bossé, Jon Rogers, Lucy A. Weinert, Matt T. G. Holden, Olusegun Oshota, Paul R. Langford, Roberto Fernandez Crespo, Roy R. Chaudhuri, Stephanie Walker, Susanna M. Williamson, Tom Atherton, Yanwen Li   +17 more
core   +3 more sources

Photoredox Autocatalysis: Towards a Library of Generally Applicable Sulfonamide Reductive Photocatalysts

Angewandte Chemie International Edition, EarlyView.
Photoredox autocatalysis is revealed to access cyclic biaryl sulfonamides (BASNs) without an initial exogenous photocatalyst. While unveiling photoredox autocatalysis is important to the enrichment of basic research, this has also led to further practical applications such as rapid discovery of novel, potent and readily accessible photocatalyst ...
Jaspreet Kaur, Mark John P. Mandigma, Nakul Abhay Bapat, Joshua P. Barham   +3 more
wiley   +1 more source

Crystal structure of N,N-diisopropyl-4-methylbenzenesulfonamide

Acta Crystallographica Section E: Crystallographic Communications, 2020
The synthesis of the title compound, C13H21NO2S, is reported here along with its crystal structure. This compound crystallizes with two molecules in the asymmetric unit. The sulfonamide functional group of this structure features S=O bond lengths ranging
Brock A. Stenfors, Richard J. Staples, Shannon M. Biros, Felix N. Ngassa   +3 more
doaj   +1 more source