Structurally similar allosteric modulators of α7 nicotinic acetylcholine receptors exhibit five distinct pharmacological effects. [PDF]
Activation of nicotinic acetylcholine receptors (nAChRs) is associated with the binding of agonists such as acetylcholine to an extracellular site that is located at the interface between two adjacent receptor subunits.
D'Oyley, JM+4 more
core
Gas-phase acidity of sulfonamides: implications for reactivity and prodrug design [PDF]
A computational study at the density functional theory level was performed on bioactive and model sulfonamides with the aim of determining the factors affecting the acidity of the sulfonamido group.
Gomes, JRB, Gomes, P
core +1 more source
Achieving High Energy Density in Aqueous Zinc‐Ion Batteries
Aqueous zinc‐ion batteries (AZIBs) offer high safety, cost‐effectiveness, and environmental benefits, yet achieving high energy density remains a challenge. This review explores advances in cathodes, zinc anodes, separators, and electrolytes to enhance energy density. It also discusses scalability and future directions, highlighting AZIBs potential for
Chun‐Chuan Kao+5 more
wiley +1 more source
Molecularly Imprinted Polymer-Decorated Magnetite Nanoparticles for Selective Sulfonamide Detection.
Sulfonamides are known not only to be antimicrobial drugs that lead to antimicrobial resistance but also to be chemotherapeutic agents that may be allergenic and potentially carcinogenic, which represents a potentially hazardous compound once present in ...
Alejandro Zamora-Gálvez+5 more
semanticscholar +1 more source
Amidine Sulfonamides and Benzene Sulfonamides: Synthesis and Their Biological Evaluation [PDF]
New amidine and benzene sulfonamide derivatives were developed and structures of the new products were confirmed by elemental and spectral analysis (FT-IR, ESI-MS,1HNMR, and13CNMR). In vitro, developed compounds were screened for their antibacterial and antifungal activities against medically important bacterial strains, namely,S. aureus, B.
Mahmood Ahmed+4 more
openaire +3 more sources
Modeling the hydrolysis of perfluorinated compounds containing carboxylic and phosphoric acid ester functions, alkyl iodides, and sulfonamide groups [PDF]
Temperature dependent rate constants were estimated for the acid- and base-catalyzed and neutral hydrolysis reactions of perfluorinated telomer acrylates (FTAcrs) and phosphate esters (FTPEs), and the SN1 and SN2 hydrolysis reactions of fluorotelomer ...
Kaya Forest, Sierra Rayne
core +1 more source
Bridged [2.2.1] bicyclic phosphine oxide facilitates catalytic γ-umpolung addition-Wittig olefination. [PDF]
A novel bridged [2.2.1] bicyclic phosphine oxide, devised to circumvent the waste generation and burdens of purification that are typical of reactions driven by the generation of phosphine oxides, has been prepared in three steps from commercially ...
Cai, Lingchao+4 more
core +1 more source
Supercapacitors: An Emerging Energy Storage System
This review explores the principles, advancements, and material innovations in supercapacitor technology, covering pseudocapacitors, double‐layer capacitors, electrolytes, and nanostructured materials like carbon nanotubes, MXenes, and graphene. It examines hybrid systems bridging capacitors and batteries, promising applications in wearable devices ...
Muhammad Faisal Iqbal+7 more
wiley +1 more source
N-(1-Allyl-1H-indazol-5-yl)-4-methoxybenzenesulfonamide hemihydrate
In the title compound, C17H17N3O3.0.5H2O, the indazole system makes a dihedral angle of 46.19 (8)° with the plane through the benzene ring and is nearly perpendicular to the allyl group, as indicated by the dihedral angle of 81.2 (3 ...
Hakima Chicha+4 more
doaj +1 more source
(E)-4-Amino-N-(1,2-dihydropyridin-2-ylidene)benzenesulfonamide nitromethane monosolvate
In the title solvate, C11H11N3O2S·CH3NO2, the dihedral angle between the benzene ring and the N-containing ring is 85.94 (11)°, and an approximate V shape arises for the sulfonamide molecule.
Mostafa M. Ghorab+4 more
doaj +1 more source