Results 81 to 90 of about 86,041 (331)

PharmVar GeneFocus: NAT2—Genetic Variation and Updated Nomenclature

Clinical Pharmacology &Therapeutics, EarlyView.
The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly polymorphic human N‐acetyltransferase 2 (NAT2) gene. NAT2 metabolizes several clinically used drugs including isoniazid, hydralazine, amifampridine, procainamide, and sulfonamides such as dapsone, and also some highly carcinogenic arylamines.
Georgia Papanikolaou, Estella S. Poloni, José A.G. Agúndez, Raquel L.F. Teixeira, Erin C. Boone, Adalberto Rezende Santos, Michelle Whirl‐Carrillo, Katrin Sangkuhl, Teri E. Klein, Mariam R. Habil, Giannoulis Fakis, Rodney F. Minchin, David W. Hein, Sotiria Boukouvala, Andrea Gaedigk   +14 more
wiley   +1 more source

Risk of Acute Kidney Injury Associated With Nephrotoxic Burden in Hospitalized Patients: A Scoping Review

Clinical Pharmacology &Therapeutics, EarlyView.
Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Wafa Alatawi, Jessica L. Wallace, Dhakrit Rungkitwattanakul, Britney A. Stottlemyer, Tiffany L. Tran, Melanie Manis Reida, Sandra L. Kane‐Gill   +6 more
wiley   +1 more source

Crystal structure of potassium [4-amino-5-(benzo[d]thiazol-2-yl)-6-(methylsulfanyl)pyrimidin-2-yl](phenylsulfonyl)azanide dimethylformamide monosolvate hemihydrate

Acta Crystallographica Section E: Crystallographic Communications, 2019
The title compound, K+·C18H14N5O2S3−·C3H7NO·0.5H2O, was obtained in a reaction designed to deliver a neutral 2-pyrimidylbenzothiazole. The anion is deprotonated at the sulfonamide nitrogen. The asymmetric unit of the title compound contains two potassium
Rasha A. Azzam, Galal H. Elgemeie, Rokia R. Osman, Peter G. Jones   +3 more
doaj   +1 more source

Electrochemical Three‐Component Synthesis of Vinyl Sulfonamides via Decarboxylative Sulfonylation of Cinnamic Acids

ChemSusChem, EarlyView.
An efficient, metal‐free electrochemical three‐component reaction of cinnamic acids, SO2, and amines to access (E)‐β‐styryl sulfonamides is reported. Utilizing graphite electrodes and SO2 stock solutions, this decarboxylative protocol proceeds under mild conditions with high regio‐ and stereoselectivity.
Po‐Chung Chien, Harald Kelm, Georg Manolikakes   +2 more
wiley   +1 more source

Design and Synthesis of Dy₂TmSbO₇/BiHoO₃ Heterojunction: The Mechanism and Application for Photocatalytic Degradation of Sulphamethoxypyridazine

Molecules
A novel Z-scheme Dy2TmSbO7/BiHoO3 heterostructure photocatalyst was synthesized with the ultrasound-assisted solvothermal method. The Dy2TmSbO7/BiHoO3 heterojunction photocatalyst (DBHP) reflected wonderful separation efficiency of photogenerated ...
Jingfei Luan, Minghe Ma, Liang Hao, Hengchang Zeng, Anan Liu   +4 more
doaj   +1 more source

Crystal structure of methyl 1-methyl-3,5-diphenyl-7-tosyl-3,6,7,11b-tetrahydropyrazolo[4′,3′:5,6]pyrano[3,4-c]quinoline-5a(5H)-carboxylate

Acta Crystallographica Section E, 2014
In the title compound, C35H31N3O5S, the piperidine ring adopts an envelope conformation, with the methine C atom as the flap, and the pyran ring adopts a sofa conformation.
Eswar Kumar Nadendla, G. Jagadeesan, D. Kannan, Mannickam Bakthadoss, K. Gunasekaran   +4 more
doaj   +1 more source

In vivo Anti Inflammation Studies of Novel 1, 2, 5 Oxadiazole Sulfonamide Hybrids [PDF]

, 2021
Hafiz Adnan Ahmad, Muhammad Rahil Aslam, Salman Gul, Tariq Mehmood, Munawar Ali Munawar   +4 more
openalex   +1 more source

Origin of the Mobile Di-Hydro-Pteroate Synthase Gene Determining Sulfonamide Resistance in Clinical Isolates

bioRxiv, 2018
Sulfonamides are synthetic chemotherapeutic agents that work as competitive inhibitors of the di-hydro-pteroate synthase (DHPS) enzyme, encoded by the folP gene.
Miquel Sánchez-Osuna, P. Cortés, J. Barbé, Ivan Erill   +3 more
semanticscholar   +1 more source

Molecular Layer Deposition for Surface Modification of Emerging Battery Systems

EcoEnergy, EarlyView.
This review provides a timely and comprehensive survey on the applications of molecular layer deposition (MLD) in surface modifications of emerging battery systems, including lithium‐ion batteries (LIBs), lithium metal batteries (LMBs), sodium‐based batteries (NBs), and solid‐state batteries (SSBs).
Xiangbo Meng
wiley   +1 more source

Determination of quinolones and sulfonamides residues in aquatic products and livestock products with enhanced matrix removal-lipid adsorbent by liquid chromatography-tandem mass spectrometry

Shipin yu jixie
ObjectiveTo establish a new method for simultaneous detection of quinolones (QNs) and sulfonamides (SAs) in aquatic products and livestock products.MethodsIn pretreatment, this work compares the effect of extraction solvents on the recoveries and ...
QIN Yu, XUE Feng, YU Junjie, LIU Yang, GONG Heng   +4 more
doaj   +1 more source