Results 171 to 180 of about 37,484 (257)

Discovery of 4‐Quinazolinone‐Containing Phenylalanine Derivatives as Potent, Resistant‐Tolerant HIV Capsid Inhibitors

open access: yesMedComm, Volume 7, Issue 5, May 2026.
Novel phenylalanine derivatives were identified as HIV‐1 capsid inhibitors. IC‐2i showed significant anti‐HIV‐1 activity at picomolar concentrations. ABSTRACT The HIV‐1 capsid (CA) is a validated antiviral target that plays critical roles in both the early and late stages of the viral life cycle.
Xujie Zhang   +18 more
wiley   +1 more source

Laryngeal Transplantation in Cancer Patients: Evaluation of Surgical Outcomes and Functional Recovery

open access: yesMedComm, Volume 7, Issue 5, May 2026.
Our pilot clinical study in laryngeal transplantation achieved divergent outcomes: two cases maintained functional speech/swallowing with around 2 year graft survival and have been ongoing, while two succumbed to sepsis (10mo) and hemorrhagic recurrence (11mo).
Zheng Jiang   +9 more
wiley   +1 more source

Towards a Scalable, AI‐Augmented Purification Platform for Amphetamine‐Type Stimulants: From Nanopolymer Synthesis to Predictive Process Simulation

open access: yesPolymers for Advanced Technologies, Volume 37, Issue 5, May 2026.
ABSTRACT The prevalent formation of by‐products in conventional methamphetamine (MA) synthesis critically impairs final product purity, presenting a significant challenge that necessitates elaborate and costly downstream purification strategies. To overcome these limitations, this study introduces molecularly imprinted polymer (MIP)‐based nanopolymers ...
Emre Dokuzparmak   +6 more
wiley   +1 more source

Exploration of Raw and Ferromagnetic Nanocomposite Sugar Bagasse Adsorbents for Heavy Metal Removal in Wastewater: Kinetics, Isotherms, and Thermodynamics Studies

open access: yesChemistrySelect, Volume 11, Issue 19, 20 May 2026.
Sugar bagasse‐based ferromagnetic nanocomposite adsorbent excellently adsorbed heavy metal ions compared to raw bagasse. Adsorption efficiency above 80% was achieved within 10 min. Regeneration studies yielded good adsorption capacities even in the fifth regeneration cycle.
Lindokuhle Simelane, Precious Mahlambi
wiley   +1 more source

Glanders: Past, Present and Future of a Neglected Zoonosis as a Threat in Veterinary and Human Health

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
This review displays a comprehensive overview of glanders, including aetiology, epidemiology, pathogenesis, diagnosis, control strategies and ongoing eradication programs. It has also reviewed differential diagnosis and treatment both in animals and humans as well as organism's antimicrobial properties.
Yahya Kanani   +2 more
wiley   +1 more source

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