Results 171 to 180 of about 46,498 (299)

Antimicrobial Residues in a Key Cerrado River: Distribution, Persistence, and Effects on Zebrafish Embryo‐Larval Development

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT The current study aimed to quantify the antimicrobials amoxicillin (AMX), cefazolin (CFZ), chloramphenicol (CHL), metronidazole (MTZ), and sulfamethoxazole (SX) in effluents and surface water of an important Cerrado river, calculate their half‐lives, and analyze their ecotoxicity following single and combined exposures.
Náthala Maria Simão   +12 more
wiley   +1 more source

Belgian bovine veterinarians' practices and opinions on udder health‐related antimicrobial use and services

open access: yesVeterinary Record, EarlyView.
Abstract Background Changing legislation regarding antimicrobial consumption (AMC) forces Flemish bovine veterinary practitioners (BVP) to rethink their business models and shift their on‐farm practices from curative to preventive. However, little is known about their current practices and opinions regarding antibiotic stewardship, mastitis treatment ...
Lien Creytens   +2 more
wiley   +1 more source

Diagnostic antibodies at an inflection point: From discovery platforms to design‐oriented engineering

open access: yesVIEW, EarlyView.
This study systematically organizes the evolution of diagnostic antibodies from discovery platforms to design‐oriented engineering and analyzes the strengths and limitations of each approach. Meanwhile, it provides a critical, literature‐driven synthesis of current challenges, proposing integrated strategies for assay‐aware and function‐driven antibody
Qitao Song   +14 more
wiley   +1 more source

Systemic medications associate with surgically treated cataract among adults over 50 years in Finland

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen   +3 more
wiley   +1 more source

Polyfunctional sulfonamides and sulfonates and process for preparing them

open access: yes
The present invention relates to a process for preparing sulfonyl halides comprising the steps of a) reacting an enoxymetal, allylsilane or allylstannane compound, preferably in the presence of a diene, with sulphur dioxide and b) adding a suitable ...
Bouchez, Laure   +3 more
core  

Generation of equine‐specific local antibiograms: reproductive tract of mares and fillies in Western Australia

open access: yesAustralian Veterinary Journal, EarlyView.
Introduction Antimicrobial resistance (AMR) may lead to increasing inefficacy and treatment failure of bacterial infections in the future. Antimicrobial stewardship (AMS) programmes are critical to ensuring the continued efficacy of available antimicrobials.
JKH Hoong, C Boyd, C Secombe, D Byrne
wiley   +1 more source

Targeting protein–protein interactions with reversible covalent modalities: Non‐cysteine chemistries

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Protein–protein interactions (PPIs) are central to diverse cellular functions, and represent a rapidly expanding class of therapeutic targets. Advancements in covalent drug design have enabled small‐molecule drugs to overcome challenges associated with engaging these targets, such as limited durations of action and difficult‐to‐drug (expansive,
Ruchira Basu, Steven Fletcher
wiley   +1 more source

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