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From Antibacterial to Antitumour Agents: A Brief Review on The Chemical and Medicinal Aspects of Sulfonamides.

Mini-Reviews in Medical Chemistry, 2020
BACKGROUND Sulfonamides have been in clinical use for many years and the development of bioactive substances containing the sulfonamide subunit has grown steadily in view of their important biological properties such as antibacterial, antifungal ...
Helloana Azevedo-Barbosa   +4 more
semanticscholar   +1 more source

Biodegradation of sulfonamides in both oxic and anoxic zones of vertical flow constructed wetland and the potential degraders.

Environmental Pollution, 2020
The pollution of wastewater with antibiotics and antibiotics resistance genes has attracted public concerns about ecosystem and global health. Swine wastewater can contain high concentrations of antibiotics, especially sulfonamides, even after full-scale
Jianfei Chen   +3 more
semanticscholar   +1 more source

Single and simultaneous adsorption of three sulfonamides in agricultural soils: Effects of pH and organic matter content.

Science of the Total Environment, 2020
Veterinary antibiotics reaching the environment have become a matter of global concern, since they can cause serious negative impacts on human and ecological health.
M. Conde-Cid   +6 more
semanticscholar   +1 more source

Sulfonamide hypersensitivity

Immunology and Allergy Clinics of North America, 2004
Sulfonamide antibiotics can result in a wide variety of hypersensitivity reactions. No validated diagnostic tests are available for sulfonamide reactions; therefore, clinicians must rely on the combination of a careful patient history, review of medical records, and a sound knowledge base regarding the common clinical manifestations of sulfonamide ...
Christopher G, Slatore   +1 more
openaire   +2 more sources

Selective degradation of splicing factor CAPERα by anticancer sulfonamides.

Nature Chemical Biology, 2017
Target-protein degradation is an emerging field in drug discovery and development. In particular, the substrate-receptor proteins of the cullin-ubiquitin ligase system play a key role in selective protein degradation, which is an essential component of ...
Taisuke Uehara   +15 more
semanticscholar   +1 more source

Spherical mesoporous covalent organic framework as a solid-phase extraction adsorbent for the ultrasensitive determination of sulfonamides in food and water samples by liquid chromatography-tandem mass spectrometry.

Journal of Chromatography A, 2020
Efficient extraction of polar sulfonamides antibiotics from aqueous samples and food is very challenging, because they are hydrophilic, their concentration is very low, and the matrix is complex. Covalent organic frameworks (COFs), a novel porous organic
Lianlei Wen   +5 more
semanticscholar   +1 more source

Ecological and human health risk of sulfonamides in surface water and groundwater of Huixian karst wetland in Guilin, China.

Science of the Total Environment, 2019
Sulfonamide antibiotics are contaminants of emerging concern (CEC). These CECs raise considerable alarm because they are commonly present in water environments. Studies on the environmental existence of CECs in karst areas of Guilin (Southern China) have
L. Qin   +6 more
semanticscholar   +1 more source

Sequential C-S and S-N Coupling Approach to Sulfonamides.

Organic Letters, 2020
A one-pot three-component reaction involving nitroarenes, (hetero)arylboronic acids, and potassium pyrosulfite leading to sulfonamides was described.
Kai Chen   +5 more
semanticscholar   +1 more source

Copper-Catalyzed Remote C(sp3 )-H Trifluoromethylation of Carboxamides and Sulfonamides.

Angewandte Chemie, 2019
Reported herein is an unprecedented protocol for trifluoromethylation of unactivated aliphatic C(sp3 )-H bonds. With Cu(OTf)2 as the catalyst, the reaction of N-fluoro-substituted carboxamides (or sulfonamides) with Zn(CF3 )2 complexes provides the ...
Zhonglin Liu   +5 more
semanticscholar   +1 more source

Effects of prepolymerization on surface molecularly imprinted polymer for rapid separation and analysis of sulfonamides in water.

Journal of Colloid and Interface Science, 2020
This work systematically investigated the effects of prepolymerization on the property of multi-templates surface molecularly imprinted polymer (MIP), which was utilized to quickly and simultaneously separate and detect six sulfonamides (sulfadiazine ...
Yinming Fan, Guolong Zeng, Xiaoguo Ma
semanticscholar   +1 more source

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