Results 231 to 240 of about 113,455 (289)
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Journal of Allergy and Clinical Immunology, 2013
CLINICAL VIGNETTE A 48-year-old man was referred to our clinic with high-grade intermittent fever for 8 days and a generalized rash for 3 days. Threeweeks before presentation, the patient had been started on 5 mg/d prednisolone, 50 mg of diclofenac twice daily, 20 mg/d omeprazole, and 2 g/d of sulfasalazine for symptomatic ankylosing spondylitis ...
Schnyder Benno, Pichler Werner J
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CLINICAL VIGNETTE A 48-year-old man was referred to our clinic with high-grade intermittent fever for 8 days and a generalized rash for 3 days. Threeweeks before presentation, the patient had been started on 5 mg/d prednisolone, 50 mg of diclofenac twice daily, 20 mg/d omeprazole, and 2 g/d of sulfasalazine for symptomatic ankylosing spondylitis ...
Schnyder Benno, Pichler Werner J
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Mini-Reviews in Medical Chemistry, 2020
BACKGROUND Sulfonamides have been in clinical use for many years and the development of bioactive substances containing the sulfonamide subunit has grown steadily in view of their important biological properties such as antibacterial, antifungal ...
Helloana Azevedo-Barbosa +4 more
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BACKGROUND Sulfonamides have been in clinical use for many years and the development of bioactive substances containing the sulfonamide subunit has grown steadily in view of their important biological properties such as antibacterial, antifungal ...
Helloana Azevedo-Barbosa +4 more
semanticscholar +1 more source
Sequential C-S and S-N Coupling Approach to Sulfonamides.
Organic Letters, 2020A one-pot three-component reaction involving nitroarenes, (hetero)arylboronic acids, and potassium pyrosulfite leading to sulfonamides was described.
Kai Chen +5 more
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Journal of Pharmaceutical Sciences, 1972
An evaluation of entropies and enthalpies of transition and fusion and a comparison of X-ray diffraction patterns and IR spectra of polymorphic forms of structurally related compounds were undertaken to obtain information which might prove useful in correlating the frequency of occurrence of polymorphism with certain aspects of chemical structure ...
Shiu Shiang Yang, J. Keith Guillory
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An evaluation of entropies and enthalpies of transition and fusion and a comparison of X-ray diffraction patterns and IR spectra of polymorphic forms of structurally related compounds were undertaken to obtain information which might prove useful in correlating the frequency of occurrence of polymorphism with certain aspects of chemical structure ...
Shiu Shiang Yang, J. Keith Guillory
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Copper-Catalyzed Remote C(sp3 )-H Trifluoromethylation of Carboxamides and Sulfonamides.
Angewandte Chemie, 2019Reported herein is an unprecedented protocol for trifluoromethylation of unactivated aliphatic C(sp3 )-H bonds. With Cu(OTf)2 as the catalyst, the reaction of N-fluoro-substituted carboxamides (or sulfonamides) with Zn(CF3 )2 complexes provides the ...
Zhonglin Liu +5 more
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Stimulation of human T cells with sulfonamides and sulfonamide metabolites
Journal of Allergy and Clinical Immunology, 2010Exposure to sulfonamides is associated with a high incidence of hypersensitivity reactions. Antigen-specific T cells are involved in the pathogenesis; however, the nature of the antigen interacting with specific T-cell receptors is not fully defined.We sought to explore the frequency of sulfamethoxazole (SMX)- and SMX metabolite-specific T cells in ...
Werner J. Pichler +6 more
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Journal of Internal Medicine, 1972
AbstractTwo cases of hepatitis induced by sulfonamides are described. The causative relationship was verified by the administration of a test dose. The administration caused in both cases a prompt appearance of clinical reaction followed by a rise of serum bilirubin and enzyme activities, which subsided within 10 days.
A, Konttinen, J O, Peräsalo, A, Eisalo
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AbstractTwo cases of hepatitis induced by sulfonamides are described. The causative relationship was verified by the administration of a test dose. The administration caused in both cases a prompt appearance of clinical reaction followed by a rise of serum bilirubin and enzyme activities, which subsided within 10 days.
A, Konttinen, J O, Peräsalo, A, Eisalo
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Some sulfonamides as aldose reductase inhibitors: therapeutic approach in diabetes
Archives of Physiology and Biochemistry, 2020In this study, aldose reductase (AR) was purified from sheep kidney using chromatographic methods and examined the interactions between some sulfonamides and the enzyme.
Yeliz Demir, Zeynep Köksal
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Trends in sensitive detection and rapid removal of sulfonamides: A review.
Journal of Separation Science, 2020Sulfonamides in environmental water, food, and feed are a major concern for both aquatic ecosystems and public health, because they may lead to the health risk of drug resistance.
Xintong Xie +3 more
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Copper-Catalyzed Arylation of Remote C(sp3 )-H Bonds in Carboxamides and Sulfonamides.
Angewandte Chemie, 2018Reported herein is an unprecedented copper-catalyzed arylation of remote C(sp3 )-H bonds. Stirring a trifluorotoluene solution of either N-fluorocarboxamides or N-fluorosulfonamides and arylboronic acids in the presence of a catalytic amount of copper(II)
Zhaodong Li, Qian Wang, Jieping Zhu
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