Results 41 to 50 of about 32,232 (288)

Cell‐Delivering Injectable Hydrogels with Tunable Microporous Structures Improve Therapeutic Efficacy for Volumetric Muscle Loss

Advanced Functional Materials, EarlyView.
The study presents an injectable hydrogel with tunable microporosity to improve mesenchymal stem cell delivery for volumetric muscle loss treatment. Mesenchymal stem cells encapsulated in porous hydrogels significantly promote the spreading, proliferation, and cytokine secretion of mesenchymal stem cells.
Hana Yasue, Tetsushi Taguchi, Taka‐Aki Asoh, Akihiro Nishiguchi   +3 more
wiley   +1 more source

2-Benzoyl-4-phenyl-1,2,5-thiadiazol-3(2H)-one 1,1-Dioxide

Molbank
3,5-Diphenyl-4H-1,2,6-thiadiazin-4-one treated with meta-chloroperoxybenzoic acid undergoes an oxidative ring contraction to give 2-benzoyl-4-phenyl-1,2,5-thiadiazol-3(2H)-one 1,1-dioxide in a 29% yield, the structure of which is supported by single ...
Emmanouil Broumidis, Samuel B. H. Patterson, Georgina M. Rosair, Panayiotis A. Koutentis, Andreas S. Kalogirou   +4 more
doaj   +1 more source

Controlled Release of Human Dental Pulp Stem Cell‐Derived Exosomes from Hydrogels Attenuates Temporomandibular Joint Osteoarthritis

Advanced Healthcare Materials, EarlyView.
Exosomes can reduce tissue damage in temporomandibular joint osteoarthritis (TMJOA), but rapid clearance limits their efficacy. This study encapsulates exosomes in hyaluronic acid hydrogels for controlled release. In a rat model, hydrogel‐encapsulated exosomes outperform free exosomes in preserving bone integrity and reducing tissue destruction ...
Victor Diez‐Guardia, Yajing Tian, Yunzhe Guo, Jiaying Li, Shengjie Cui, Cécile A. Dreiss, Eileen Gentleman, Xuedong Wang   +7 more
wiley   +1 more source

erythro-{1-Bromo-1-[(1-phenylethyl)sulfonyl]ethyl}benzene

IUCrData
The title compound, C16H17BrO2S, crystallizes as the erythro (RR/SS) isomer of a pair of sulfones that were diastereomeric due to chirality of the α-carbon atoms on the sulfone sulfur atom.
Peter W. R. Corfield
doaj   +1 more source

Synthesis, Biological Evaluation and Molecular Docking of Certain Sulfones as Potential Nonazole Antifungal Agents

Molecules, 2016
We reported herein the synthesis, antifungal activity, docking and in silico ADME prediction studies of four novel series of sulfones 6a–f, 8a–c, 10a–f and 12a–c.
Mohamed Fares, Mohamed A. Said, Muhammad A. Alsherbiny, Radwa A. Eladwy, Hadia Almahli, Marwa M. Abdel-Aziz, Hazem A. Ghabbour, Wagdy M. Eldehna, Hatem A. Abdel-Aziz   +8 more
doaj   +1 more source

Enhanced safety of sulfone-based electrolytes for lithium-ion batteries: broadening electrochemical window and enhancing thermal stability

Energy Materials and Devices, 2023
To meet the demands of high-voltage lithium-ion batteries (LIBs), we develop a novel electrolyte through theoretical calculations and electrochemical characterization.
Qiaojun Li, Wenya Wu, Yu Li, Haixia Ren, Chuan Wu, Ying Bai   +5 more
doaj   +1 more source

Immunosuppressive Cytokine‐Tethered Hydrogel for Treating Rheumatoid Arthritis

Advanced Healthcare Materials, EarlyView.
An injectable hydrogel is developed by chemically tethering IL‐4, an immunosuppressive cytokine, to a hyaluronic acid‐based backbone. The hydrogel reduces joint friction and exerts immunomodulatory effects. In a rheumatoid arthritis (RA) mouse model, it reduced inflammation, preserved cartilage, and promoted anti‐inflammatory immune responses.
Woojin Back, Moonkyoung Jeong, Huyen‐Thao Le, Ji‐Ho Park   +3 more
wiley   +1 more source

Sulfide, Sulfoxide, and Sulfone Derivatives of Usnic Acid as Inhibitors of Human TDP1 and TDP2 Enzymes

Chemistry
Tyrosyl-DNA phosphodiesterases 1 and 2 (TDP1 and TDP2) are important DNA repair enzymes that remove various adducts from the 3′- and 5′-ends of DNA, respectively.
Aleksandr S. Filimonov, Marina A. Mikhailova, Nadezhda S. Dyrkheeva, Irina A. Chernyshova, Tatyana E. Kornienko, Konstantin A. Naumenko, Rashid O. Anarbaev, Andrey A. Nefedov, Chigozie Achara, Anthony D. M. Curtis, Olga A. Luzina, Konstantin P. Volcho, Nariman F. Salakhutdinov, Olga I. Lavrik, Jóhannes Reynisson   +14 more
doaj   +1 more source

Crystal structure of N,N-dimethyl-2-[(4-methylbenzyl)sulfonyl]ethanamine

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the crystal, the title compound, C12H19NO2S, has a disordered structure with two equally populated conformations of the amine fragment. A pair of weak C—H...O intermolecular interactions between the CH2 and SO2 groups gives a one-dimensional ...
Alan R. Kennedy, Abedawn I. Khalaf, Fraser J. Scott, Colin J. Suckling   +3 more
doaj   +1 more source

THERAPEUTICAL: Sulfonal in Insanity [PDF]

The Journal of Nervous and Mental Disease, 1895
n ...
openaire   +2 more sources