Results 71 to 80 of about 26,603 (276)

Sulfonylurea prescriptions overall and in subjects 65 or older.

, 2019
SU: sulfonylurea.
Amanda K. Kitten (7244921), Kelly R. Reveles (7244927), Laurajo Ryan (5921381), Meghan Kamath (7244924)   +3 more
core   +1 more source

Identification of antitumor sulfonylurea binding proteins of HeLa plasma membranes [PDF]

, 1995
Plasma membranes of cultured HeLa S cells bound the tritiated antitumor sulfonylurea [3H]LY181984 with high affinity (Kd of about 25 nM). The number of binding sites, estimated to represent 30 to 35 pmol/mg protein, would represent a low abundance ...
Lawrence, James, Wilkinson, Francis E., James Morré, D., Paulik, Mark, Cho, NaMi   +4 more
core   +1 more source

Correlations Among Glycemia and Glucose Variability, Thyroid Hormones, and Albuminuria in Patients With Type 2 Diabetes Mellitus

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Hyperglycemia, glucose fluctuations, and thyroid dysfunction contribute to the progression of diabetic nephropathy. This study aimed to investigate the associations of glycemia, glucose variability, and thyroid hormones with albuminuria in patients with type 2 diabetes mellitus (T2DM). In total, 451 T2DM patients were included.
Na Luo, Shang‐Yong Feng, Hui Chen, Dun‐Min She, Yan Liu, Ying Li, Cai‐Feng Yan, Zhen‐Wen Zhang, Jing Chen, Xiao‐Li Cai, Gao‐Yu Zhao, Hui Yu, Yan Wang   +12 more
wiley   +1 more source

Conformational Polymorphism in Sulfonylurea Drugs: Electronic Structure Analysis

, 2010
Quantum chemical calculations have been performed using HF, B3LYP, and MP2 methods on the model sulfonylurea PhSO2NHC(═O)NHMe to understand the conformational and tautomeric preferences.
Kasetti, Yoganjaneyulu, Nikunj K. Patel, Bharatam, Prasad V., Yoganjaneyulu Kasetti, Prasad V. Bharatam, Patel, Nikunj K., Sandeep Sundriyal, Sundriyal, Sandeep   +7 more
core   +1 more source

Effects of Vascular Photobiomodulation on Glycemic Control in Patients With Type II Diabetes Mellitus: A Prospective Single‐Arm Clinical Study

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Objective This study aimed to evaluate the effects of laser photobiomodulation (PBM) using the systemic vascular technique (VPBM) on glycemic control in individuals with type 2 diabetes mellitus (T2DM) undergoing conventional pharmacological treatment.
Leandro Augusto Almeida, Anne Missrie, Victor Augusto Ramos Fernandes, Patricia Brassolatti, Ana Laura Martins de Andrade   +4 more
wiley   +1 more source

Pharmacogenetics of sulfonylurea-induced hypoglycemia in type 2 diabetes patients: The SUCLINGEN study

, 2021
Aim: This study investigated the incidence of sulfonylurea-induced hypoglycemia and its predictors in Type 2 diabetes (T2D) patients. Patients & methods: In this prospective, observational study, T2D patients on maximal sulfonylurea-metformin therapy ...
Vethakkan, Shireene Ratna, Hussein, Zanariah, Huri, Hasniza Zaman, Loganadan, Navin Kumar   +3 more
core   +1 more source

Sulfonylurea Receptor Pharmacology Alters the Performance of Two Central Pattern Generating Circuits in Cancer borealis

Function
Neuronal activity and energy supply must maintain a fine balance for neuronal fitness. Various channels of communication between the two could impact network output in different ways.
Sonal Kedia, Naziru M Awal, Jackie Seddon, Eve Marder   +3 more
doaj   +1 more source

From ions to insulin

eLife, 2017
Electron cryo-microscopy has revealed the three-dimensional structure of a potassium channel that has a central role in regulating the release of insulin from the pancreas.
Voula Kanelis
doaj   +1 more source

Large language models unlock large text corpora in the search for data on medicinal plants and fungi

PLANTS, PEOPLE, PLANET, EarlyView.
Millions of people worldwide depend on plants and fungi for their healthcare needs, yet our understanding of which species are used medicinally—and how—remains fragmented and incomplete. As part of Kew's Plants for Health service, we developed a pipeline to mine large text corpora for information on natural products, initially focusing on the medicinal
Adam Richard‐Bollans, Francesco Civita, Tiziana A. Cossu, Ifra Saifi, Kristina Patmore, Caroline Wilkinson, Bob Allkin   +6 more
wiley   +1 more source

Bioequivalence Study of a New Generic Fixed-Dose Combination of Sitagliptin (100 mg) and Glimepiride (2 mg) in Healthy Adult Volunteers under Fasting Condition

Chronicle of Diabetes Research and Practice
Introduction: The present study evaluated the bioequivalence of a fixed-dose combination (FDC) of sitagliptin and glimepiride with the originator reference product.
Prashant Kumthekar, Mihir Upadhyay, Koripalli S. Reddy, Sambasiva R. Puram, Basava S. Nallamekala   +4 more
doaj   +1 more source