Results 81 to 90 of about 26,552 (294)

Meta‐analysis of sotagliflozin, a dual sodium‐glucose‐cotransporter 1/2 inhibitor, for heart failure in type 2 diabetes

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 968-979, April 2025.
Abstract Sodium‐glucose co‐transporters (SGLTs) mediate sodium and glucose transport across cell membranes. SGLT2 inhibitors have a recognized place within heart failure (HF) guidelines. We evaluated the effect of sotagliflozin on HF and cardiovascular outcomes in participants with type 2 diabetes. Scopus, Medline, Embase and Central were searched from
Maria Anna Bantounou   +7 more
wiley   +1 more source

Synthesis and efficacy of herbicidal ionic liquids with chlorsulfuron as the anion

open access: yesOpen Chemistry, 2020
In the framework of this research, four new herbicidal ionic liquids (HILs) comprising chlorsulfuron as the anion were synthesized and characterized.
Praczyk Marcin   +4 more
doaj   +1 more source

Conformational Polymorphism in Sulfonylurea Drugs: Electronic Structure Analysis

open access: yes, 2016
Quantum chemical calculations have been performed using HF, B3LYP, and MP2 methods on the model sulfonylurea PhSO2NHC(O)NHMe to understand the conformational and tautomeric preferences.
Nikunj K. Patel (2268253)   +3 more
core   +1 more source

Diabetes Increases Immunotherapy‐Related Toxicity but Not Efficacy in Metastatic Non‐Small Cell Lung Cancer: A Multicenter Retrospective Study

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT This multicenter retrospective study evaluated the impact of type 2 diabetes mellitus (DM) on clinical outcomes and immune‐related adverse events (irAEs) in 450 patients with metastatic non‐small cell lung cancer (NSCLC) treated with second‐line nivolumab at 17 centers between 2016 and 2024. Among these patients, 118 (26.2%) had DM.
Emre Çakır   +32 more
wiley   +1 more source

SEPARATION OF SULFONYLUREA METABOLITES IN WATER BY CAPILLARY ELECTROPHORESIS

open access: yes, 1995
The potential of capillary electrophoresis (CE) for the separation and detection of the metabolites of nine sulfonylurea herbicides in aqueous solution was evaluated.
VICARI A, BONETTI A, DINELLI G
core   +1 more source

Artificial intelligence‐assisted nanozyme design for medical and environmental applications

open access: yesJournal of Intelligent Medicine, EarlyView.
AI‐assisted nanozyme design integrates cross‐source data and machine learning to enable predictive structure‐activity relationships, accelerating intelligent diagnostics, precision therapeutics, and environmental surveillance. Abstract Nanozymes, a class of nanomaterials with intrinsic enzyme‐like catalytic activities, have emerged as promising ...
Xiaolin Guo   +7 more
wiley   +1 more source

Sulfonylurea prescriptions overall and in subjects 65 or older.

open access: yes, 2019
SU: sulfonylurea.
Amanda K. Kitten (7244921)   +3 more
core   +1 more source

Identification of antitumor sulfonylurea binding proteins of HeLa plasma membranes [PDF]

open access: yes, 1995
Plasma membranes of cultured HeLa S cells bound the tritiated antitumor sulfonylurea [3H]LY181984 with high affinity (Kd of about 25 nM). The number of binding sites, estimated to represent 30 to 35 pmol/mg protein, would represent a low abundance ...
Lawrence, James   +4 more
core   +1 more source

Impact of Dapagliflozin on MRI‐Derived Epicardial Adipose Tissue: Secondary Imaging Analysis of a Randomized Trial

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Epicardial adipose tissue (EAT) is a metabolically active fat depot associated with cardiovascular risk and represents a modifiable imaging biomarker. Studies have shown that sodium–glucose cotransporter‐2 (SGLT2) inhibitors reduce EAT thickness in patients with type 2 diabetes mellitus (T2DM). However, it is unclear whether this is
Min Jae Cha   +9 more
wiley   +1 more source

Conformational Polymorphism in Sulfonylurea Drugs: Electronic Structure Analysis

open access: yes, 2010
Quantum chemical calculations have been performed using HF, B3LYP, and MP2 methods on the model sulfonylurea PhSO2NHC(═O)NHMe to understand the conformational and tautomeric preferences.
Kasetti, Yoganjaneyulu   +7 more
core   +1 more source

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