Results 11 to 20 of about 26,603 (276)

Unintentional sulfonylurea toxicity due to a drug–drug interaction: a case report [PDF]

BMC Research Notes, 2018
Background Sulfonylureas are widely used for type 2 diabetes mellitus, but these medications carry a risk of hypoglycemia. Drug–drug interactions that inhibit sulfonylurea metabolism and thus increase systemic exposure can cause unintentional ...
Keith Gunaratne, Emily Austin, Peter E. Wu   +2 more
doaj   +2 more sources

Assessing the environmental risks of sulfonylurea pollutants: Insights into the risk priority and structure-toxicity relationships

Ecotoxicology and Environmental Safety
Sulfonylureas are widely used herbicides globally; however, the health risks associated with exposure to these compounds are poorly understood. This study used fuzzy clustering to categorize 44 sulfonylurea compounds into three risk priority levels (I ...
Zhi-Cong He, Tao Zhang, Xin-Fang Lu, Rui Li, Wei Peng, Fei Ding   +5 more
doaj   +2 more sources

Risk of new-onset prostate cancer for Metformin versus Sulfonylurea use in Type 2 Diabetes Mellitus: A propensity score-matched study [PDF]

, 2022
The aim of this study was to compare the risks of new-onset prostate cancer between metformin and sulfonylurea users with type 2 diabetes mellitus (T2DM).
Liu, Xuejin, Hui, Kyle, Liu, Tong, Wai, Abraham Ka Chung, Lee, Teddy Tai Loy, Lee, Sharen, Zhou, Jiandong, Chan, Jeffrey Shi Kai, Tse, Gary, Lee, Yan Hiu Athena, Wong, Wing Tak, Zhang, Qingpeng, Ng, Kenrick, Dee, Edward Christopher, Hui, Jeremy Man Ho   +14 more
core   +2 more sources

Characterization of the rat mesangial cell type 2 sulfonylurea receptor [PDF]

, 1999
Background. Sulfonylurea receptors are classified as either high- affinity type 1 (SUR1) or low-affinity type 2 receptors (SUR2), and the gene expression of SURs has recently been demonstrated in kidney. However, functional data regarding a renal SUR are
Garvin, Jeffrey L, Rodríguez-Barbero, Alicia, Riser, Bruce L, Cortes, Pedro, Szamosfalvi, Balázs, Asano, Kenichiro, Yee, Jerry   +6 more
core   +2 more sources

Adsorption of nicosulfuron herbicide in the agricultural soils of Bosnia and Herzegovina

Plant, Soil and Environment, 2020
In this study, the sorption characteristics of nicosulfuron herbicide in soils from different agricultural regions of Bosnia and Herzegovina, as well as factors influencing the sorption process, were evaluated.
Amer Sunulahpašić, Siniša Mitrić, Dragana Šunjka, Mirjana Žabić, Tihomir Predić, Milan Šipka, Luka Rodić   +6 more
doaj   +1 more source

Dynamics of total volume of pancreatic α‐ and β ‐cells under the influence sulfonylureas and their combination with dipeptidyl peptidase‐4 inhibitors

Endocrinology, Diabetes & Metabolism, 2021
Objective Sulfonylureas and dipeptidyl peptidase‐4 inhibitors have a multidirectional effect on pancreatic cells. We aimed to evaluate the effects of these drugs on β‐ and α‐cells in rats aged 12 months with type 2 diabetes mellitus when administered in ...
Tuchina Taisiia Pavlovna, Skotnikova Kseniia Petrovna, Vtorushina Anna Anatolievna, Uskov Ivan Sergeyevich, Rogoza Olga Vladimirovna, Grozov Roman Viktorovich, Babenko Alina Yurievna, Galagudza Mikhail Mikhailovich   +7 more
doaj   +1 more source

Deintensification of Treatment with Sulfonylurea and Insulin after Severe Hypoglycemia among Older Adults with Diabetes [PDF]

, 2021
Importance: Practice guidelines recommend deintensification of hypoglycemic agents among older adults with diabetes who are at high risk of hypoglycemia, yet real-world treatment deintensification practices are not well characterized.
Bradley, M.C., Alexopoulos, A.-S., Kahkoska, A.R., Thorpe, C., Buse, J., Niznik, J., Stürmer, T., Pate, V.   +7 more
core   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Should sulfonylurea be discontinued or maintained at the lowest dose when starting ipragliflozin? A multicenter observational study in Japanese patients with type 2 diabetes

Journal of Diabetes Investigation, 2019
Aims/Introduction We investigated the difference in efficacy and safety between discontinuation and maintaining of sulfonylurea when adding a sodium–glucose cotransporter 2 inhibitor.
Kiyohiko Takahashi, Kyu Yong Cho, Akinobu Nakamura, Aika Miya, Arina Miyoshi, Chiho Yamamoto, Hiroshi Nomoto, Hirokatsu Niwa, Kiyohito Takahashi, Naoki Manda, Yoshio Kurihara, Shin Aoki, Yoichi M Ito, Tatsuya Atsumi, Hideaki Miyoshi   +14 more
doaj   +1 more source

Reasoned opinion on the review of the existing maximum residue levels (MRLs) for mesosulfuron according to Article 12 of Regulation (EC) No 396/2005 [PDF]

EFSA Journal, 2012
According to Article 12 of Regulation (EC) No 396/2005, the European Food Safety Authority (EFSA) has reviewed the Maximum Residue Levels (MRLs) currently established at European level for the pesticide active substance mesosulfuron.
European Food Safety Authority
doaj   +1 more source