The use of metformin, sulfonylurea compounds and insulin and the risk of hip fractures in diabetic patients: a systematic review and meta-analysis of observational studies [PDF]
BMC Musculoskeletal Disorders, 2023Background Hip fracture is a major health problem that occurs more often in the elderly, especially in diabetic patients. Some studies have been conducted regarding the effect of anti- diabetic drugs on fractures.
Mansour Bahardoust+6 more
doaj +5 more sources
The Oral Hypoglycemic Sulfonylurea Compounds [PDF]
Diabetes, 1957M. G.: Mechanisms of action of the hypoglycemia-producing sulfonylurea derivatives. Ibid. p p . 894 -903 . Studies of the mechanism of action of sulfonylurea derivatives. Diabetes 6 : 5 3 , Jan.Feb., 1957.
semanticscholar +4 more sources
Sulfonylurea Compounds Uncouple the Glucose Dependence of the Insulinotropic Effect of Glucagon-Like Peptide 1 [PDF]
Diabetes, 2007Glucagon-like peptide (GLP)-1 mimetics have been reported to cause hypoglycemia when combined with sulfonylureas. This study investigated the impact of tolbutamide on the glucose dependence of the GLP-1–mediated effects on insulin, glucagon, and somatostatin secretion in the in situ perfused rat pancreas.
Jocelyn de Heer, Jens J. Holst
semanticscholar +6 more sources
Selection of rice herbicide from several sulfonylurea compounds.
Journal of Weed Science and Technology, 1985DPX-F5384, methyl 2-[[[[[(4, 6-dimethox-pyrimidin-2-yl) amino] carbonyl] amino] sulfonyl]methyl]benzoate and several analogs were examined for herbicidal activities, crop safety, and selectivity.(1) Both DPX-F5384 and DPX-T6375 which have substitutents of 2-CO2CH3 were tested in petri dishes to examine their effect during early growth stage of rice ...
Shunji TAKEDA+3 more
semanticscholar +4 more sources
Synthesis and Structure-activity Relationships of Herbicidal Thiophene Sulfonylurea Compounds
Journal of Pesticide Science, 1997In a study of sulfonylurea herbicides, we found that some thiophene sulfonylureas, substituted at the 3 position and possessing the sulfonylurea bridge at the 2 position of the thiophene ring, exhibit high herbicidal activities on paddy field application.
Masahiko Ikeguchi+3 more
semanticscholar +5 more sources
A Study of the Action of Hypoglycemia-producing Biguanide and Sulfonylurea Compounds on Oxidative Phosphorylation [PDF]
Journal of Biological Chemistry, 1962Alfredo Falcone+2 more
semanticscholar +4 more sources
Synthesis and Biological Activity Evaluation of Imidazole Heterocyclic Sulfonylurea Compounds
HETEROCYCLES, 2021Guangshan Xuan+3 more
semanticscholar +3 more sources
Metabolomic Analysis of Skin Malodor-Associated Compounds and Structure-based Prediction of Acetolactate Synthase Selective Sulfonylurea Inhibitors [PDF]
, 2021Bromhidrosis is characterized as a chronic condition related to malodor from the skin. The underlying etiology is from bacterial decompositions of glandular secretion products.
Ryan Yuki Huang
openalex +2 more sources
Treatment of chemical diabetes mellitus with sulfonylurea compounds [PDF]
Metabolism, 1973EFORE DISCUSSING the use of sulfonylurea compounds in the treatment of chemical diabetes, we must ask ourselves whether there is any evidence to indicate that mild carbohydrate intolerance may be harmful. Although this is a controversial question, there is some evidence that this may be true.
Stefan S. Fajans
openalex +5 more sources
The Development of Sulfonylurea Compounds
, 2014磺酰脲类化合物作为除草剂和降糖药应用于市场已经广为人知,它具有很好的生物活性及较小的毒性,在应用方面有着很多的可能性。目前,人们对磺酰脲类化合物的研究日趋增多,本文就其理化性质、合成方法以及生物活性进行了综述。It is well known that sulfonylurea compounds have been applied in the market as herbicides and hypoglycemic drugs.
静 田
openalex +2 more sources