Recent Developments in Diabetes Management: Exploring Receptors, Pathways, and Compounds
Diabetes mellitus (DM) is a widespread metabolic disorder with profound effects on vital organs. Often referred to as a “systemic” or “multi-organ” disorder due to the impact on key organs, such as the kidneys, pancreas, eyes, and heart, DM is ...
Pallavi Pandey +3 more
doaj +1 more source
Hongos que degradan metsulfurón metil en suelos agrícolas de Argentina [PDF]
Strains of Mucor, Penicillium and Trichoderma, able to use metsulfuron-methyl (MM) as a sole carbon and energy source, were isolated from agricultural soils in Argentina.
Bianchinotti, María Virginia +1 more
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Metformin as a Therapeutic Target in Endometrial Cancers. [PDF]
Endometrial cancer is the most common gynecologic malignancy in developed countries. Its increasing incidence is thought to be related in part to the rise of metabolic syndrome, which has been shown to be a risk factor for the development of ...
Johnson, Jennifer +6 more
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The Capital–Labour–State Dynamics of Herbicide Adoption in Rainfed India
ABSTRACT This paper engages debates around the capital–labour–state dynamics of agrarian transitions to address the oft‐studied but still little‐understood question of why farmers adopt herbicides when they do. Over the last several years, smallholder farmers in India have begun using the herbicide bispyribac sodium at breakneck speeds, particularly in
Carly Nichols, Nidhi Kumari
wiley +1 more source
Glyphosate resistance in annual ryegrass (Lolium rigidum Gaud.) with multiple resistance mechanisms. [PDF]
Glyphosate (N-(phosphonomethyl)glycine) is a post-emergent, systemic and non-selective herbicide for the control of annual and perennial weeds. This herbicide has very low toxicity to the mammals.
Bostamam, Yazid
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Treatment of type 2 diabetes by free fatty acid receptor agonists [PDF]
Dietary free fatty acids (FFAs), such as ω-3 fatty acids, regulate metabolic and anti-inflammatory processes, with many of these effects attributed to FFAs interacting with a family of G protein-coupled receptors.
Hudson, Brian D. +3 more
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ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RA) improve outcomes in heart failure (HF) with preserved ejection fraction. Whether GLP‐1 RA prevent new‐onset HF in Type 2 diabetes or obesity requires further investigation. Methods We performed an updated meta‐analysis of randomized placebo‐controlled trials (RCT) of treatment ...
João Sérgio Neves +8 more
wiley +1 more source
A cardiologic approach to non-insulin antidiabetic pharmacotherapy in patients with heart disease
Classical non-insulin antihyperglycemic drugs currently approved for the treatment of type 2 diabetes mellitus (T2DM) comprise five groups: biguanides, sulfonylureas, meglitinides, glitazones and alpha-glucosidase inhibitors.
Fisman Enrique Z, Tenenbaum Alexander
doaj +1 more source
Metabolomic Analysis of Skin Malodor-Associated Compounds and Structure-based Prediction of Acetolactate Synthase Selective Sulfonylurea Inhibitors [PDF]
Ryan Yuki Huang
openalex +1 more source
Crystallization of Arabidopsis thaliana acetohydroxyacid synthase in complex with the sulfonylurea herbicide chlorimuron ethyl [PDF]
Acetohydroxyacid synthase (AHAS; EC 2.2.1.6) catalyses the formation of 2-acetolactate and 2-aceto-2-hydroxybutyrate as the first step in the biosynthesis of the branched-chain amino acids valine, leucine and isoleucine. The enzyme is inhibited by a wide
Duggleby, R. G. +2 more
core +1 more source

