Results 171 to 180 of about 1,582,904 (250)

Dipeptidyl Peptidase‐4 Inhibitors Associated Heart Failure Events in Adult Patients With Type‐2 Diabetes Mellitus Treated With Dipeptidyl Peptidase‐4 Inhibitors: A Systematic Review and Meta‐Analysis

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
DPP‐4 Inhibitors associated withheart failure events in patients with type‐2 diabetes. This study found statistically insignificant summary effect for all DPP‐4 inhibitors combined but found asignificant association of saxagliptin with heart failure events (RR = 1.24, 95% CI 1.05–1.47). Results are to be interpreted with caution.
Shishir Nepal, Shiva Prasad Nepal
wiley   +1 more source

Causal association between antidiabetic drug targets and risk of Bell's palsy: A 2-sample Mendelian randomization study. [PDF]

Medicine (Baltimore)
Lu K, Ye L, Yi X, He Y.
europepmc   +1 more source

Impact of Semaglutide, Liraglutide and Tirzepatide on Cardiometabolic Outcomes: A Comparative Narrative Review

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
The comparative pharmacology and cardiometabolic outcomes of semaglutide, liraglutide and tirzepatide, integrating evidence from major clinical trial programs and meta‐analyses. ABSTRACT Background Cardiometabolic disorders such as type 2 diabetes mellitus (T2DM), obesity and cardiovascular disease (CVD) remain major global health challenges.
Hiba Bawadi, Haya Abuhijleh, Mamon Nofal, Zain Z. Zakaria, Maha Al‐Asmakh   +4 more
wiley   +1 more source

Five-year follow-up of incretin-based therapy in a patient with KCNJ11-related permanent neonatal diabetes: Achieving insulin discontinuation and sulfonylurea reduction. [PDF]

J Diabetes Investig
Ohkuma T, Aotani R, Sakamoto W, Oshiro A, Ago T.   +4 more
europepmc   +1 more source

Temporal Trends in Colorectal Cancer Associated With Type 2 Diabetes Mellitus in U.S. Adults, 1999–2023: A CDC Wonder Database Analysis—A Population‐Based Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Colorectal cancer (CRC) and type 2 diabetes mellitus (T2DM) are significant contributors to global morbidity and mortality, with growing evidence suggesting a synergistic impact on disease outcomes. This research focused on analyzing trends in CRC‐related deaths among individuals with coexisting T2DM in the United States ...
Waleed Tariq, Neha Waseem, Mehreen Maka, Bushra Ubaid, Sheetal Verma, Yusra Ejaz, Maryam Owais, Awais Tariq, Soha Waseem, Iftikhar Khan, Ehsanullah Alokozay, Muhammad Hassan Tariq, Shahzaib Ahmed, Shoaib Ahmad   +13 more
wiley   +1 more source

The Impact of Polymers in Amorphous Solid Dispersion on the Bioavailability of Sulfonylureas and Meglitinides. [PDF]

Drug Des Devel Ther
Aulifa DL, Wibisono TTDW, Ningsih JD, Christy GDAB, Pertiwi DS, Praja HM, Gazzali AM, Amaliah S, Budiman A.   +8 more
europepmc   +1 more source

Association of Glucagon‐Like Peptide‐1 Receptor Agonists With Cancer Risk in Older Adults With Type 2 Diabetes

Obesity, Volume 34, Issue S2, Page 75-87, September 2026.
ABSTRACT Objective The real‐world evidence on the association between glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) and cancer risk remains limited and mixed. Methods In 2013–2020 national Medicare claims data, we included cancer‐naïve patients with type 2 diabetes (T2D). We identified those who initiated GLP‐1 RA, sodium‐glucose cotransporter 2
Ying Lu, Hao Dai, Huilin Tang, William T. Donahoo, Thomas J. George, Ramon C. Sun, Sizun Jiang, Aik Choon Tan, Yi Guo, Jonathan D. Licht, John M. Allen, Kelvin P. Lee, Jingchuan Guo, Jiang Bian   +13 more
wiley   +1 more source

Safety and Efficacy of Glucagon‐Like Peptide‐1 Receptor Agonists Use in Elderly People With Obesity—A Meta‐Analysis

Obesity, Volume 34, Issue S2, Page 25-35, September 2026.
ABSTRACT Objective This meta‐analysis evaluates the safety and efficacy of glucagon‐like peptide‐1 receptor agonists (GLP‐1 RA) for the treatment of older adults with obesity compared to younger individuals. Methods A systematic review was conducted following PRISMA guidelines (PROSPERO CRD420251074381).
Inês Rego de Figueiredo, Filipa Sofia Simas, Angela Ghiletchi, João Oliveira Torres, José Silva‐Nunes   +4 more
wiley   +1 more source

Design, <i>in Vitro</i> Biological Activities and Molecular Dynamics Simulations of Novel Chalcone and Pyrazole Derivatives Targeting α‑Glucosidase and PPAR‑γ as Antidiabetic Agents. [PDF]

ACS Omega
Kurşun Aktar BS, Taşdemir D, Sağlam E, Kaya S, Yılmaz GT, Şahin Yağlioğlu A, Oruç-Emre EE.   +6 more
europepmc   +1 more source

Integrative In Silico Profiling of Major Phytochemicals From a Sclerocarya birrea–Nauclea latifolia–Piper longum Mixture: Docking, Molecular Dynamics, ADMET, and Ligand‐Based Target Prediction on Shared Pathways in Type 2 Diabetes Mellitus and Alzheimer's Disease

ChemistryOpen, Volume 15, Issue 9, September 2026.
Which major phytochemical from the Sclerocarya birrea–Nauclea latifolia–Piper longum mixture engages shared targets across the T2DM–AD axis? Integrated docking, triplicate 100‐ns molecular dynamics, post‐MD MM‐GBSA, and ADMET/target prediction prioritize QR‐PME, which forms stable GSK3β and TACE complexes with binding energy estimates comparable to ...
Jean Philippe Djientcheu Tientcheu, Erman Salih İstifli   +1 more
wiley   +1 more source