Screening of binding by antidiabetic drugs to normal vs AGE-modified human serum albumin through covalent immobilization and microscale affinity chromatography. [PDF]
Woolfork AG +3 more
europepmc +1 more source
Integrating Conventional and Emerging Approaches in Cardiovascular Risk Assessment and Management
Conventional risk factors (hypertension, dyslipidaemia, diabetes, smoking, obesity and physical inactivity) account for roughly 70% of population‐attributable cardiovascular risk and anchor a proposed three‐tier pathway: universal low‐cost assessment (Tier 1), selective testing such as hsCRP or PRS where it would change management (Tier 2) and resource‐
Sana Rasheed +4 more
wiley +1 more source
Determination of Fluorinated Pesticide Residues and Their Selected Transformation Products in High-Water-Content Foods Using Complementary LC-MS/MS and GC-MS/MS Methods. [PDF]
Wenio I +5 more
europepmc +1 more source
ABSTRACT Background Hip and knee replacement are common procedures with an increasing focus on same‐day surgery. However, capacity constraints limit the number of eligible patients actually being scheduled for same‐day discharge, calling for further selection of those with the highest likelihood of same‐day discharge.
Christoffer C. Jørgensen +11 more
wiley +1 more source
Evaluation of %CV and average glucose derived from pre- and postprandial 6-point glucose measurements for assessing hypoglycemia risk. [PDF]
Soga R +4 more
europepmc +1 more source
ABSTRACT Aims There is no proven treatment to prevent the growth or rupture of abdominal aortic aneurysm (AAA). As an aneurysm enlarges over time, the risk of fatal aortic rupture increases. Metformin, a drug usually prescribed to treat Type 2 diabetes, has previously been associated with reduced AAA risk in observational studies. Our aim was to assess
Katie Louise Saxby +5 more
wiley +1 more source
Comparative safety of sulfonylurea therapies on cardiovascular and severe hypoglycemia outcomes among adults with type 2 diabetes and moderate cardiovascular risk: a target trial emulation. [PDF]
Sklepinski S +15 more
europepmc +1 more source
ABSTRACT Aim Patients with chronic kidney disease (CKD) have an increased cardiovascular risk. Since neutrophils and neutrophil‐borne proteins contribute to cardiovascular disease, we analyzed the neutrophil phenotype in patients with CKD who presented with a spectrum of cardiovascular comorbidities.
Sonja Vondenhoff +22 more
wiley +1 more source
Effectiveness of empagliflozin in reducing hypoglycemic events as compared to sulfonylurea in type 2 diabetes patients during fasting in Ramadan: a single-center study. [PDF]
Kiran Z +5 more
europepmc +1 more source
ABSTRACT Aims ONWARDS 10 assessed switching from daily basal insulins to once‐weekly insulin icodec without a one‐time additional dose at first injection. Materials and Methods In this treat‐to‐target, open‐label, 26‐week, phase 3b trial, adults with basal‐insulin‐treated type 2 diabetes (T2D) with glycated haemoglobin [HbA1c] 7.0%–10.0% were ...
Julio Rosenstock +5 more
wiley +1 more source

