Results 111 to 120 of about 10,498 (275)

Engineering Marker‐Free Lettuce Chloroplast Genome to Express Functional Glucagon‐Like Peptide‐1 Receptor Agonists Exenatide and Lixisenatide

Plant Biotechnology Journal, EarlyView.
Engineering of marker‐free lettuce chloroplast genome to express CTB‐Exenatide and CTB‐Lixisenatide for oral delivery. Upper panel: Chemically synthesised exenatide or lixisenatide require expensive production, purification, refrigeration and invasive delivery methods.
Rahul Singh, Henry Daniell
wiley   +1 more source

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

The Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand, Jakub Tomek, Blanca Rodriguez   +2 more
wiley   +1 more source

Synthesis and Pharmacological Evaluation of New N-Sulfonylureas as NLRP3 Inflammasome Inhibitors: Identification of a Hit Compound to Treat Gout

, 2022
Paloma Narros‐Fernández, Mourad Chioua, Sonia A. Petcu, Daniel Diez‐Iriepa, Laura Cerrada‐Gálvez, Celine Decouty‐Pérez, Alejandra Palomino‐Antolín, Eva Ramos, Víctor Farré‐Alins, Ana Belén López-Rodríguez, Alejandro Romero, José Marco‐Contelles, Javier Egea   +12 more
openalex   +1 more source

14‐3‐3 proteins: Regulators of cardiac excitation–contraction coupling and stress responses

The Journal of Physiology, EarlyView.
Abstract figure legend 14‐3‐3 protein interactions in cardiac regulation. Schematic representation of 14‐3‐3 binding partners in excitation–contraction coupling, transcriptional regulation/development and stress response pathways. Asterisks indicate targets where the exact 14‐3‐3 binding site is unknown.
Heather C. Spooner, Rose E. Dixon
wiley   +1 more source

Natural degradation ways of herbicides of sulfonylurea group [PDF]

, 2013
Currently in agriculture much attention is paid to development and use of low-cost and at the same time effective methods of fight against weeds. In this regard, widely purchased sulfonylurea herbicides.
Akhramovich, T. I., Ignatovets, O. S., Lazovskaya, O. I., Leontiev, V. N.   +3 more
core  

Functional expression of inwardly rectifying and ATP‐sensitive potassium channels in human pulmonary artery smooth muscle and endothelial cells

The Journal of Physiology, EarlyView.
Abstract figure legend Inwardly rectifying (Kir2) and ATP‐sensitive (KATP) potassium channels are functionally expressed in human pulmonary artery endothelial and smooth muscle cells. The schematic illustrates how Kir2‐ and KATP‐mediated K+ efflux contributes to VM regulation and pulmonary vascular tone.
Bianca Barreira, Daniel Morales‐Cano, Laura Moreno, Beatriz de Olaiz, Rui Adão, Angel Cogolludo, Francisco Perez‐Vizcaino, Maria Sancho   +7 more
wiley   +1 more source

Mitokondriális eredetű nitrogén szabadgyökök és ATP-függő K-csatornák szerepe az organellum működésében = The involvement of mitochondrial-derived nitrogen radicals and mitoK-ATP channels in the regulation of organelle function [PDF]

, 2009
Elsőként a mitoKATP csatornák alegységeit terveztük azonosítani humán szív mintákon. A kísérletek során megbizonyosodtunk afelől, hogy a korábban ilyen csatornáknak gondolt fehérjék nincsenek jelen megfelelő számban és formában a mitokondriális ...
Csordás, Attila, Horváth, Eszter Mária, Lacza, Zsombor, Pankotai, Eszter, Szabó, Csaba   +4 more
core  

Incidence of Interspecific Hybrids Resulting from Open Field Pollination of Wild Turnip Populations with Herbicide‐Resistant Rape Pollen

New Zealand Journal of Crop and Horticultural Science, Volume 54, Issue 1, March 2026.
Cultivated rape (Brassica napus L.) and wild turnip (Brassica rapa var. oleifera DC) can be readily hybridised by manual hand pollination and represent a crop‐weed combination with high potential for introgression of crop alleles into weed populations.
Toni E. Jenkins, Christopher M. A. Frampton, Anthony J. Conner   +2 more
wiley   +1 more source

Machine Learning Assisted Fluorescent Sensor Array for Sensing Applications

Advanced Sensor Research, Volume 5, Issue 2, February 2026.
Chemical analysis is being revolutionized by the combination of the high‐dimensional, multi‐channel signals generated by fluorescent sensor arrays and the powerful data analysis enabled by machine learning. This review covers state‐of‐the‐art studies that use machine learning techniques for the identification and quantification of fluorescent sensor ...
Haobo Guo, Karandeep Grover, Elizabeth J. New   +2 more
wiley   +1 more source

Associations of Albuminuria and Metabolic Syndrome Traits With Fracture Risk in Patients With Type 2 Diabetes: A Population‐Based Cohort Study

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Type 2 diabetes is associated with an increased risk of fragility fractures. While obesity may protect against fractures, individuals with type 2 diabetes often exhibit other metabolic syndrome (MetS) traits and albuminuria. We evaluated their roles and synergistic implications on incident fractures, stratified by obesity status ...
Xi Xiong, David T. W. Lui, Chengsheng Ju, Xiaodong Liu, Li Wei, Manju Chandran, Carlos K. H. Wong   +6 more
wiley   +1 more source