Results 111 to 120 of about 3,641,920 (285)

Efficacy and Safety of Automated Insulin Delivery in People With Type 2 Diabetes: A Systematic Review and Meta‐Analysis

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Studies evaluating automated insulin delivery (AID) in type 2 diabetes are limited in number and often conducted in small cohorts. We aimed to summarize efficacy and safety data through a systematic review and meta‐analysis. Materials and Methods We searched MEDLINE, PubMed, Web of Science, and CENTRAL databases and performed hand ...
Sergio Di Molfetta, Ludovico Di Gioia, Irene Caruso, Mariangela Caporusso, Sebastio Perrini, Annalisa Natalicchio, Luigi Laviola, Francesco Giorgino   +7 more
wiley   +1 more source

Safety of anagliptin/metformin combination tablets evaluated by non‐inferiority between pre‐ and post‐serum lactic acid levels in Japanese patients with type 2 diabetes and moderate renal impairment (AMELIO STUDY)

Journal of Diabetes Investigation, EarlyView.
To investigate the safety of anagliptin/metformin combination tablets in Japanese patients of type 2 diabetes with moderate renal impairment. This study demonstrates that the fixed‐dose combination of anagliptin and metformin can be used safely in patients with type 2 diabetes complicated by moderate renal dysfunction.
Hiroshi Kajio, Ryotaro Bouchi, Mitsuhisa Komatsu, Masanori Yamazaki, Daisuke Takarabe, Masahide Okamoto, Takahisa Tanaka, Toru Kitazawa, Hisayuki Katsuyama, Yasumichi Mori, Mitsuhiko Noda   +10 more
wiley   +1 more source

Natural degradation ways of herbicides of sulfonylurea group [PDF]

, 2013
Currently in agriculture much attention is paid to development and use of low-cost and at the same time effective methods of fight against weeds. In this regard, widely purchased sulfonylurea herbicides.
Akhramovich, T. I., Ignatovets, O. S., Lazovskaya, O. I., Leontiev, V. N.   +3 more
core  

Diabetic foot ulcer‐related amputation is associated with twofold increased risk of cardiovascular disease: A Korean National Health Information Database Study

Journal of Diabetes Investigation, EarlyView.
Data/Design: Nationwide, population‐based longitudinal cohort using the Korean National Health Insurance Service health checkup database (index 2009–2012) with follow‐up through December 31, 2018. Population/Exposure: Adults with diabetes (N = 1,229,689); DFU‐related amputation at baseline (n = 1,486) vs no DFU‐related amputation.
Jinsun Jang, Bong‐Seong Kim, Hye Won Yang, Heejun Son, Dong Yeon Lee, Min Gyu Kyung, Hwan Jun Jae, Saebeom Hur, Sang Wha Kim, Sanghyun Ahn, Kyung‐Do Han, Soo Heon Kwak   +11 more
wiley   +1 more source

Novel chemotype NLRP3 inhibitors that target the CRID3-binding pocket with high potency

Life Science Alliance
The NLRP3 inflammasome drives various diseases. Here, we describe novel potent and selective NLRP3-targeted inhibitors to bolster pharmacological studies and development of NLRP3-targeted therapies.
Lieselotte Vande Walle, Madhukar Said, Oonagh Paerewijck, Arinna Bertoni, Marco Gattorno, Bruno Linclau, Mohamed Lamkanfi   +6 more
doaj   +1 more source

Evaluation of %CV and average glucose derived from pre‐ and postprandial 6‐point glucose measurements for assessing hypoglycemia risk

Journal of Diabetes Investigation, EarlyView.
Six‐point pre‐ and postprandial glucose values were extracted from CGM to calculate average glucose and %CV. ROC analysis identified AG <167.7 mg/dL and %CV >21.6% as key risk factors, enabling simple detection of high hypoglycemia risk using limited glucose measurements. ABSTRACT Aims/Introduction This study determined the usefulness of coefficient of
Rika Soga, Keiichi Torimoto, Fumi Uemura, Yosuke Okada, Shingo Nakayamada   +4 more
wiley   +1 more source

Mitokondriális eredetű nitrogén szabadgyökök és ATP-függő K-csatornák szerepe az organellum működésében = The involvement of mitochondrial-derived nitrogen radicals and mitoK-ATP channels in the regulation of organelle function [PDF]

, 2009
Elsőként a mitoKATP csatornák alegységeit terveztük azonosítani humán szív mintákon. A kísérletek során megbizonyosodtunk afelől, hogy a korábban ilyen csatornáknak gondolt fehérjék nincsenek jelen megfelelő számban és formában a mitokondriális ...
Csordás, Attila, Horváth, Eszter Mária, Lacza, Zsombor, Pankotai, Eszter, Szabó, Csaba   +4 more
core  

Impact of renal function on antidiabetic drug selection in Japan: A real‐world analysis using the J‐DREAMS database

Journal of Diabetes Investigation, EarlyView.
Using a large Japanese real‐world database, we examined antidiabetic drug selection in first and second therapy stratified by renal function and study period. The earlier initiation of SGLT2 inhibitors and GLP‐1 receptor agonists increased over time, particularly in second therapy, with prescribing patterns increasingly aligned across renal function ...
Masashi Kubota, Mitsuru Ohsugi, Kohjiro Ueki   +2 more
wiley   +1 more source

Association of glucagon‐like peptide‐1 receptor agonist use with clinical outcomes in patients with rheumatoid arthritis and type 2 diabetes

Journal of Diabetes Investigation, EarlyView.
This TriNetX (US, 2016–2023) study compared clinical outcomes in patients with rheumatoid arthritis and type 2 diabetes treated with GLP‐1 receptor agonists vs DPP4 inhibitors. ABSTRACT Objectives To evaluate whether glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) are associated with improved survival and renal outcomes in patients with ...
Yu‐Ting Yu, Ying Chun Lee, Yu‐Wei Fang, Wen‐Hui Hsieh, Ming‐Hsien Tsai   +4 more
wiley   +1 more source

The Generics Revolution and the New Economic Geography of the Global Pesticide Industry

Journal of Agrarian Change, EarlyView.
ABSTRACT The global pesticide industry transformed from one dominated by patented products and legacy multinationals with strong manufacturing bases in the United States and EU to one dominated by generic products produced in India and China. We use proprietary market research data, data from regulatory filings, industry press and bilateral trade data ...
Christian Berndt, Marion Werner, Finn Mempel, Annie Shattuck, Zackary Okun Dunivin   +4 more
wiley   +1 more source