Results 131 to 140 of about 10,468 (295)

Relation Between Structure of Sulfonylurea Compounds and their Effect on Frog Muscle Metabolism.

Experimental Biology and Medicine, 1958
SummaryThe effect of sulfonylbutylurea derivatives on frog muscle metabolism depends upon the molecular group substituted on the benzene ring para to the main chain of the molecule. Substitution of an amino group produces an inhibitory compound; absence of any group or substitution of either a methoxy or a carboxyl radical produces a compound with ...
openaire   +2 more sources

Phytotherapeutic Regulation of Matrix Metalloproteinases in Diabetic Foot Ulcer: Molecular Mechanisms and Wound Healing Perspectives

Phytochemicals in Food and Medicine, Volume 1, Issue 2, June 2026.
Chronic inflammation in diabetic foot ulcers elevates MMP activity and suppresses TIMP and growth factor signaling, impairing tissue repair. Phytochemicals modulate NF‐κB/MAPK pathways and enhance Nrf2–TIMP expression, restoring MMP/TIMP balance, promoting collagen deposition, angiogenesis, and re‐epithelialization, leading to effective wound healing ...
Vishnu Priyan Elaiyaraja, Eswara Rajagopal, Subhikssha Babu, Balaji Sadhasivam   +3 more
wiley   +1 more source

Modulation of KATP channels by diazoxide preserves mitochondrial function and barrier integrity under staurosporine‐induced epithelial stress

British Journal of Pharmacology, Volume 183, Issue 12, Page 3213-3233, June 2026.
Background and Purpose Intestinal barrier dysfunction caused by mitochondrial stress, oxidative damage and apoptosis, are hallmarks of dysbiosis‐associated gastrointestinal (GI) disorders. Staurosporine causes downstream features of dysbiosis‐induced epithelial damage.
Fatima Maqoud, Eleonora Malerba, Simona Drago, Antonella Orlando, Domenica Mallardi, Nicoletta De Lucia, Marina Antonacci, Annamaria Di Turi, Domenico Tricarico, Francesco Russo   +9 more
wiley   +1 more source

Natural degradation ways of herbicides of sulfonylurea group [PDF]

, 2013
Currently in agriculture much attention is paid to development and use of low-cost and at the same time effective methods of fight against weeds. In this regard, widely purchased sulfonylurea herbicides.
Akhramovich, T. I., Ignatovets, O. S., Lazovskaya, O. I., Leontiev, V. N.   +3 more
core  

Clinically significant hypoglycaemia in hospitalised adults: A multicentre study of 1205 episodes in the United Kingdom

Diabetic Medicine, Volume 43, Issue 6, June 2026.
Abstract Introduction and Objectives Inpatient hypoglycaemia is a serious complication of diabetes therapy, yet real‐world data on clinically significant episodes remain limited. The objectives of this study are (1) to describe the clinical and biochemical characteristics of clinically significant inpatient hypoglycaemia across multiple NHS sites, (2 ...
Charles Page, Mariam Idrissi, Sam Sherratt‐Mayhew, Aashritha Buchipudi, Amanda Ling Jie Yee, Kalyaani Persad, Aqeelah Khatoon, Amrit Rakkar, Amynta Arshad, Alexandra Lubina Solomon, Rajeev Raghavan, Lakshmi Rengarajan, Ahmed Iqbal, Pratik Choudhary, Aspasia Manta, Punith Kempegowda, DEVI Collaboration   +16 more
wiley   +1 more source

Sex‐Specific Associations of Inflammatory Biomarkers With All‐Cause and Cardiovascular Mortality Across Glycaemic Status: A Prospective UK Biobank Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 4728-4740, June 2026.
ABSTRACT Aims To explore sex‐specific heterogeneity in the prognostic discrimination of inflammatory markers for mortality across different glycaemic states. Methods This prospective cohort study included 450 438 participants from the UK Biobank (median follow‐up: 15.3 years), stratified by sex and glycaemic status.
Yawen Zhang, Menghan Li, Manrong Xu, Yun Shen, Lianxi Li, Gang Hu   +5 more
wiley   +1 more source

GCMS profiling of bioactive phytocompounds from Curculigo orchiodes Gaertn. root extract and evaluation of antioxidant, and antidiabetic activities: A computational drug development approach.

PLoS ONE
Curculigo orchioides (C. orchioides), a traditionally valued medicinal plant, has been utilized for centuries in the management of various ailments, but its full spectrum of therapeutical potentials remains underexplored.
Imran Mahmud, Md Khalid Saifullah, Md Niaj Morshed, Md Arju Hossain, Naznin Shahria, Apurba Kumar Barman, Famim Ahmed, Md Jakaria Islam, Toufiq Ejaj Khan, Nripendra Nath Biswas   +9 more
doaj   +1 more source

Over-expression of a specific soybean GmGSTU4 isoenzyme improves chloroacetanilide herbicide tolerance of transgenic tobacco plants [PDF]

, 2015
Plant glutathione transferases (GSTs) have a major role in herbicide detoxification. Soybean (Glycine max L.) GmGSTs have been well studied for their correlation in herbicides selectivity towards diphenyl ether, chloroacetanilide and sulfonylurea ...
AthanasiosTsaftaris,, Benekos, Kostantinos, Kissoudis, Christos, Labrou, Nikolaos E., Madesis, Panagiotis, Nianiou-Obeidat, Irini, Voulgari, Georgia   +6 more
core  

Association of GLP‐1 Receptor Agonists With Hepatic Decompensation in the All of Us Research Program

Diabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 4837-4846, June 2026.
ABSTRACT Aims To evaluate the association between glucagon‐like peptide‐1 receptor agonist (GLP‐1RA) initiation and the risk of hepatic decompensation compared with dipeptidyl peptidase 4 inhibitors (DPP4is) in a racially and ethnically diverse cohort of adults with Type 2 diabetes.
Inyoung Hwang, Yun Kim, Sang Won Lee
wiley   +1 more source

Engineering Herbicide Cross‐Resistance in Rapeseed by Generating Stacked BnaALS Mutations via Sequential CBE and ABE8e‐SpRY Editing

Plant Biotechnology Journal, EarlyView.
Sichao Ren, Wenjing Lei, Jiaqi He, Meng Jia, Yu Liu, Jialin Fan, Yumei Wang, Li Lin, Hui Zhang, Youping Wang, Jian Wu   +10 more
wiley   +1 more source