Results 31 to 40 of about 1,377,243 (284)

Cardiovascular Outcomes Comparison of Dipeptidyl Peptidase-4 Inhibitors versus Sulfonylurea as Add-on Therapy for Type 2 Diabetes Mellitus: a Meta-Analysis

open access: yesJournal of Lipid and Atherosclerosis, 2021
Objective Recent studies have raised concern about the cardiovascular safety of dipeptidyl peptidase-4 (DPP4) inhibitors. We performed a systematic review through meta-analysis to compare cardiovascular outcomes of sulfonylurea (SU) versus DPP4 ...
Won Kyeong Jeon   +3 more
doaj   +1 more source

Alkaline Soil Degradation and Crop Safety of 5-Substituted Chlorsulfuron Derivatives

open access: yesMolecules, 2022
Sulfonylurea herbicides can lead to serious weed resistance due to their long degradation times and large-scale applications. This is especially true for chlorsulfuron, a widely used acetolactate synthase inhibitor used around the world.
Lei Wu   +5 more
doaj   +1 more source

Design, Synthesis and in Vivo Evaluation of Novel Glycosylated Sulfonylureas as Antihyperglycemic Agents

open access: yesMolecules, 2015
Sulphonylurea compounds have versatile activities such as antidiabetic, diuretic, herbicide, oncolytic, antimalarial, antifungal and anticancer. The present study describes the design, synthesis and in vivo testing of novel glycosylated aryl sulfonylurea
Ghadeer A. R. Y. Suaifan   +4 more
doaj   +1 more source

Sulfonylurea is associated with higher risks of ventricular arrhythmia or sudden cardiac death compared with metformin: A population-based cohort study [PDF]

open access: yes, 2022
Background Commonly prescribed diabetic medications such as metformin and sulfonylurea may be associated with different arrhythmogenic risks. This study compared the risk of ventricular arrhythmia or sudden cardiac death between metformin and ...
Jeremy Man Ho Hui   +13 more
core  

Novel Sulfonylurea Derivatives as Potential Antimicrobial Agents: Chemical Synthesis, Biological Evaluation, and Computational Study

open access: yesAntibiotics, 2023
Methicillin-resistant Staphylococcus aureus (MRSA) is a worldwide health threat and has already tormented humanity during its long history, creating an urgent need for the development of new classes of antibacterial agents.
Fan-Fei Meng   +8 more
doaj   +1 more source

Successful sulfonylurea treatment in a patient with permanent neonatal diabetes mellitus with a novel mutation [PDF]

open access: yesKorean Journal of Pediatrics, 2015
Permanent neonatal diabetes mellitus refers to diabetes that occurs before the age of 6 months and persists through life. It is a rare disorder affecting one in 0.2-0.5 million live births.
Sung Yeon Ahn, Gu-Hwan Kim, Han-Wook Yoo
doaj   +1 more source

In Silico Study of Mangostin Compounds and Its Derivatives as Inhibitors of α-Glucosidase Enzymes for Anti-Diabetic Studies

open access: yesBiology, 2022
Diabetes is a chronic disease with a high mortality rate worldwide and can cause other diseases such as kidney damage, narrowing of blood vessels, and heart disease. The concomitant use of drugs such as metformin, sulfonylurea, miglitol, and acarbose may
Ahmad Fariz Maulana   +3 more
doaj   +1 more source

Molecular basis of sulfonylurea herbicide inhibition of acetohydroxyacid synthase [PDF]

open access: yes, 2003
Acetohydroxyacid synthase (AHAS) (acetolactate synthase, EC 4.1.3.18) catalyzes the first step in branchedchain amino acid biosynthesis and is the target for sulfonylurea and imidazolinone herbicides.
Pang, S. S.   +6 more
core   +1 more source

Insulinoma Causing Hypoglycemia in a Patient with Type 2 Diabetes

open access: yesJournal of the Formosan Medical Association, 2007
Insulinoma in a patient with pre-existing diabetes is extremely rare. A 74-year-old woman with type 2 diabetes mellitus who had been treated with a sulfonylurea for 6 years began experiencing frequent episodes of hypoglycemia.
Wei-Yi Lei   +5 more
doaj   +1 more source

Synthesis and Characterization of Related Substances of Torasemide

open access: yesPharmaceutical Fronts, 2022
Torasemide, a pyridine-3-sulfonylurea derivative, is a high-efficiency loop diuretic. During the process development of torasemide, five process-related substances, which have been specified in the pharmacopeia, would be produced.
Jiong Chen   +3 more
doaj   +1 more source

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