Results 121 to 130 of about 3,641,920 (285)

The Capital–Labour–State Dynamics of Herbicide Adoption in Rainfed India

Journal of Agrarian Change, EarlyView.
ABSTRACT This paper engages debates around the capital–labour–state dynamics of agrarian transitions to address the oft‐studied but still little‐understood question of why farmers adopt herbicides when they do. Over the last several years, smallholder farmers in India have begun using the herbicide bispyribac sodium at breakneck speeds, particularly in
Carly Nichols, Nidhi Kumari
wiley   +1 more source

Effects of Glucagon‐Like Peptide‐1 Receptor Agonists (Mono and Combination Therapy) on Energy Expenditure: A Scoping Review

Obesity Reviews, EarlyView.
ABSTRACT Introduction Weight loss results in reduced energy expenditure (EE) due to body composition alterations (e.g., fat‐free mass and fat mass losses) and mass‐independent adaptations in EE (e.g., hormones). Glucagon‐like peptide‐1 receptor agonists (GLP‐1RA) are indicated for obesity management; however, their effects on EE remain unclear ...
Flavio T. Vieira, ZhiDi Deng, Manfred J. Muller, Giovanna G. L. Bergamasco, Sarah Cawsey, Melania Manco, Steven B. Heymsfield, Carla M. Prado, Andrea M. Haqq   +8 more
wiley   +1 more source

Engineering Marker‐Free Lettuce Chloroplast Genome to Express Functional Glucagon‐Like Peptide‐1 Receptor Agonists Exenatide and Lixisenatide

Plant Biotechnology Journal, EarlyView.
Engineering of marker‐free lettuce chloroplast genome to express CTB‐Exenatide and CTB‐Lixisenatide for oral delivery. Upper panel: Chemically synthesised exenatide or lixisenatide require expensive production, purification, refrigeration and invasive delivery methods.
Rahul Singh, Henry Daniell
wiley   +1 more source

Evaluating associations between the benefits and risks of drug therapy in type 2 diabetes: a joint modeling approach

Clinical Epidemiology, 2018
John M Dennis,1 Beverley M Shields,2 Angus G Jones,2 Ewan R Pearson,3 Andrew T Hattersley,2 William E Henley1 On behalf of the MASTERMIND consortium 1Health Statistics Group, University of Exeter Medical School, Exeter, UK; 2National Institute for ...
Dennis JM, Shields BM, Jones AG, Pearson ER, Hattersley AT, Henley WE   +5 more
doaj  

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

The Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand, Jakub Tomek, Blanca Rodriguez   +2 more
wiley   +1 more source

Computational studies for pre-evaluation of pharmacological profile of gut microbiota-produced gliclazide metabolites

Frontiers in Pharmacology
BackgroundGliclazide, a second-generation sulfonylurea derivative still widely used as a second-line treatment for type 2 diabetes mellitus, is well known to be subject to interindividual differences in bioavailability, leading to variations in ...
Maja Đanić, Nebojša Pavlović, Dragana Zaklan, Bojan Stanimirov, Slavica Lazarević, Hani Al-Salami, Momir Mikov   +6 more
doaj   +1 more source

14‐3‐3 proteins: Regulators of cardiac excitation–contraction coupling and stress responses

The Journal of Physiology, EarlyView.
Abstract figure legend 14‐3‐3 protein interactions in cardiac regulation. Schematic representation of 14‐3‐3 binding partners in excitation–contraction coupling, transcriptional regulation/development and stress response pathways. Asterisks indicate targets where the exact 14‐3‐3 binding site is unknown.
Heather C. Spooner, Rose E. Dixon
wiley   +1 more source

Chemical control strategies for Poa annua in managed turfgrass systems

Crop, Forage &Turfgrass Management, Volume 12, Issue 1, June 2026.
Abstract Poa annua L. is a widespread and persistent weed in managed turfgrass systems, exhibiting both annual and short‐lived perennial growth habits. Effective management requires an integrated approach, with chemical herbicides remaining a primary tool.
James D. McCurdy, Rebecca G. Bowling, Aaron J. Patton, Edicarlos B. de Castro, James T. Brosnan, David E. Ervin, Shawn D. Askew, Clebson G. Gonçalves, Matthew T. Elmore, J. Scott McElroy, Brandon C. McNally, Benjamin D. Pritchard, John E. Kaminski, Travis W. Gannon, J. Bryan Unruh, Muthukumar V. Bagavathiannan   +15 more
wiley   +1 more source

Not All GLP‐1 Receptor Agonists Are Alike: Real‐World Evidence of Differential Endocrine and Dermatologic Safety

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 4, May 2026.
ABSTRACT Aims Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) are widely used for metabolic disorders, but emerging safety concerns include alopecia and reproductive or endocrine‐related adverse events (AEs). This study investigated the association between specific GLP‐1 RAs and these endocrine‐related AEs using a large‐scale pharmacovigilance ...
Nai Lee, Yun Kim
wiley   +1 more source

Haemoglobin A1c Time‐In‐Range and Mortality in Adults With Diabetes

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 3, May 2026.
Reduced A1c time in range and particularly greater time below range are associated with increased mortality in adults with diabetes. A1c stability within person‐specific ranges may be a risk predictor for major outcomes in adults with diabetes. ABSTRACT Introduction Glycemic variability over time is a risk factor for diabetes complications.
Paul R. Conlin, Julia C. Prentice, David C. Mohr, Libin Zhang, Donglin Li, Erin Pleasants, Richard E. Nelson, Suma Vupputuri, Gregory A. Nichols   +8 more
wiley   +1 more source