Results 171 to 180 of about 3,697,166 (278)

Real‐World Effectiveness and Safety of iGlarLixi in People With Type 2 Diabetes in LATAM Region: A Subanalysis of the SUCCESS Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 9, Page 8724-8728, September 2026.
Juan Manuel Arteaga‐Diaz, Jose Luis Torres‐Grajales, Leobardo Sauque‐Reyna, Carlos Salamanca‐Carrillo, Luis Anguiano‐Medrano   +4 more
wiley   +1 more source

Impact of Metformin Use on Clinical and Pathological Outcomes in Breast Cancer Patients With Type 2 Diabetes

Cancer Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Breast cancer is the most common malignancy in women, and its incidence is increasing worldwide. Type 2 diabetes mellitus (T2DM) is a significant comorbidity in patients with breast cancer that negatively affects prognosis. Metformin, a first‐line antidiabetic drug, has been suggested to possess antineoplastic properties. This study
Ensiyeh Bahadoran, Monir Mirzadeh, Mohsen Jafari, Yazdan Zafari, Sahar Moghbelinejad   +4 more
wiley   +1 more source

Revealing the role of increased SK3 expression in sulfonylurea resistance triggered by prolonged exposure. [PDF]

Nutr Diabetes
Park JG, Kim M, Yoo S, Hwang SW, Mok J, Park J, Kang KW.   +6 more
europepmc   +1 more source

Effects of ketogenic and low‐carbohydrate diet on glucose and weight control in type 2 diabetes mellitus patients along with metabolome change

Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
Both the low‐carbohydrate diet (LCD) and the ketogenic diet (KD) positively affect body weight and glucose metabolism in type 2 diabetes. Metabolomic signatures sensitively reflect each diet and correlate with clinical improvements – distinct metabolite associations with glycated haemoglobin and weight were identified for LCD versus KD.
Yao Wang, Haozhe He, Zhenjing Lyu, Yeyang Wang, Li Chen, Junbin Liang, Cong Lin, Huanhuan Wang, Shiping Zhang, Gugen Xu, Junzhang Tian, Kejing Zeng   +11 more
wiley   +1 more source

Integrative GC–MS, FT‐IR, and Molecular Docking Analysis of Drimycarpus racemosus (Roxb.) Hook.f ex Marchand: In Vivo Analgesic and Antidiabetic Potential

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
GC–MS profiling of D. racemosus identified bioactive phytochemicals with promising molecular interactions through docking analysis. The methanolic extract demonstrated significant antinociceptive activity against acetic acid‐ and formalin‐induced pain and exhibited antidiabetic effects in streptozotocin‐induced diabetic Swiss albino mice, supporting ...
Md Sajib Ali, Md. Rakibul Islam, M. A. Rafi, Sanjana Haque Esha, Md. Mehedi Hasan, Payar Hossain, Abdullah Ripon, Nilufar Sultana   +7 more
wiley   +1 more source

Identification and rescue of congenital hyperinsulinism-associated ABCC8 mutations that impair K_ATP channel trafficking. [PDF]

J Biol Chem
ElSheikh A, Kuo YY, Boodhansingh KE, Yang Z, Stanley CA, De Leon DD, Shyng SL.   +6 more
europepmc   +1 more source

Comparative Evaluation of the Antihyperglycemic Potential of Coccinia cordifolia and Gynura procumbens Leaf Extracts: Integrated Phytochemical, In Vivo, Molecular Docking, and DFT Investigations

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Graphical abstract illustrating the overall experimental workflow and antidiabetic evaluation of Coccinia cordifolia and Gynura procumbens extracts. Plant materials were extracted and subsequently investigated through in vivo antidiabetic studies, density functional theory (DFT) analysis, and in silico molecular docking to identify potential bioactive ...
A. J. M. Morshed, Sujan Kanti Das, Zobayed Islam, Mamuna Akter, Muhammad Abu Bakar, Mohammad Mostafa, Rasheda Akter, Tania Sharmin, Mohammad Helal Uddin   +8 more
wiley   +1 more source

Long-term efficacy and safety of tirzepatide in participants with type 2 diabetes with inadequate glycaemic control on metformin and/or sulfonylurea: Post-hoc analysis of SURPASS-4. [PDF]

Diabetes Obes Metab
Guan H, Jiang H, Yuan H, Sun J, Xu J, Ji L.   +5 more
europepmc   +1 more source

Type 2 Diabetes Mellitus: Molecular Pathogenesis and Therapeutic Interventions

MedComm, Volume 7, Issue 8, August 2026.
This graphical summary illustrates the multiorgan therapeutic landscape for Type 2 diabetes mellitus (T2D), integrating molecular pathogenesis with modern treatment strategies. It depicts how current interventions, including SGLT2 inhibitors, GLP‐1 receptor agonists, and insulin secretagogues, target key organs—kidney, pancreas, gastrointestinal tract,
Shinuan Fei, Xiyue Xiong, Lu Zhang, Jian Zhang, Lawrence W. C. Chan, Hong Jiang, Qingqing Xiong, Changtao Hu, Jie Chen, Sijun Yang   +9 more
wiley   +1 more source

Potassium channel-targeted therapy in reducing vascular complications in diabetes mellitus: novel insights. [PDF]

Front Pharmacol
Rajkovic J, Ribic A, Rekovic L, Gostimirovic M, Bukarica A, Terzic D, Gojkovic-Bukarica L.   +6 more
europepmc   +1 more source