Results 171 to 180 of about 10,468 (295)

Carrier screening in the reproductive setting—Are there medical implications for the heterozygote?—A guide for clinicians

open access: yesPregnancy, Volume 2, Issue 3, May 2026.
Abstract Carrier screening for genetic conditions performed preconception or during pregnancy allows identification of fetal risk for inherited autosomal recessive and X‐linked conditions. The goal is to identify at‐risk patients/couples and offer them reproductive options such as preimplantation genetic diagnosis, prenatal testing, or targeted newborn
Emily B. Rosenfeld   +5 more
wiley   +1 more source

GLP‐1 Receptor Agonists for Treating Alcohol Use Disorder: A Critical Review

open access: yesAlcohol, Clinical and Experimental Research, Volume 50, Issue 5, May 2026.
This narrative review of the development of GLP‐1 receptor agonists provides a foundation for both preclinical and clinical research on their use for treating alcohol use disorder (AUD). Both observational studies using real‐world data and randomized controlled clinical trials support the potential utility of these medications for treating AUD ...
Sean Woo   +6 more
wiley   +1 more source

Hypoglycemic and Hypolipidemic Effects of Leonotis mollisima Aqueous Leaf Extract in Type 2 Diabetic Rats

open access: yesJournal of Experimental Pharmacology
Namanya Stephen,1 Saidi Odoma,1 Tijjani Shinkafi Salihu,2 Aruwa Ojodale Joshua,1 Neeza Timothy1 1Department of Pharmacology, School of Pharmacy, Kampala International University-Western Campus, Bushenyi, Uganda; 2Department of Biochemistry, Kampala ...
Stephen N   +4 more
doaj  

A model‐based analysis of the CYP2C9 genotype effects on fluconazole inhibition using flurbiprofen, ketoprofen and tolbutamide as probe drugs

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 10, Page 2482-2496, May 2026.
Background The activity of CYP2C9, an important drug metabolism enzyme, is subject to the impact of genetic polymorphism. The single nucleotide polymorphism *3 is significantly associated with the increased exposure of CYP2C9 substrates. In addition, metabolic enzyme inhibitors such as fluconazole may also increase the drug exposure of CYP2C9 ...
Shen Cheng   +5 more
wiley   +1 more source

Influences of Fasting on Elimination of Sulfonylurea Compounds from Plasma in Rabbits

open access: yesYAKUGAKU ZASSHI, 1983
S, Tsukiai   +6 more
openaire   +3 more sources

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