The use of metformin, sulfonylurea compounds and insulin and the risk of hip fractures in diabetic patients: a systematic review and meta-analysis of observational studies [PDF]
Background Hip fracture is a major health problem that occurs more often in the elderly, especially in diabetic patients. Some studies have been conducted regarding the effect of anti- diabetic drugs on fractures.
Mansour Bahardoust +6 more
doaj +3 more sources
Sulfonylureas are widely used herbicides globally; however, the health risks associated with exposure to these compounds are poorly understood. This study used fuzzy clustering to categorize 44 sulfonylurea compounds into three risk priority levels (I ...
Zhi-Cong He +5 more
doaj +2 more sources
Treatment of chemical diabetes mellitus with sulfonylurea compounds [PDF]
EFORE DISCUSSING the use of sulfonylurea compounds in the treatment of chemical diabetes, we must ask ourselves whether there is any evidence to indicate that mild carbohydrate intolerance may be harmful. Although this is a controversial question, there is some evidence that this may be true.
S. S. Fajans
openaire +4 more sources
Selection of rice herbicide from several sulfonylurea compounds.
DPX-F5384, methyl 2-[[[[[(4, 6-dimethox-pyrimidin-2-yl) amino] carbonyl] amino] sulfonyl]methyl]benzoate and several analogs were examined for herbicidal activities, crop safety, and selectivity.(1) Both DPX-F5384 and DPX-T6375 which have substitutents of 2-CO2CH3 were tested in petri dishes to examine their effect during early growth stage of rice ...
Shunji TAKEDA +3 more
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A cardiologic approach to non-insulin antidiabetic pharmacotherapy in patients with heart disease [PDF]
Classical non-insulin antihyperglycemic drugs currently approved for the treatment of type 2 diabetes mellitus (T2DM) comprise five groups: biguanides, sulfonylureas, meglitinides, glitazones and alpha-glucosidase inhibitors.
Fisman Enrique Z, Tenenbaum Alexander
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Synergism of Synthetic Sulfonamides and Natural Antioxidants for the Management of Diabetes Mellitus Associated with Oxidative Stress [PDF]
In the context of expanding research on the development of compounds with multiple therapeutic actions, this study aims to consolidate findings from the last decade on new synthetic sulfonamide therapies for managing type 2 diabetes mellitus (T2DM ...
Ancuța Dinu (Iacob) +5 more
doaj +2 more sources
Metabolomic insights into the intricate gut microbial–host interaction in the development of obesity and type 2 diabetes [PDF]
Gut microbiota has recently been proposed as a crucial environmental factor in the development of metabolic diseases such as obesity and type 2 diabetes, mainly due to its contribution in the modulation of several processes including host energy ...
Magali ePalau-Rodriguez +6 more
doaj +2 more sources
Synthesis and Structure-activity Relationships of Herbicidal Thiophene Sulfonylurea Compounds
In a study of sulfonylurea herbicides, we found that some thiophene sulfonylureas, substituted at the 3 position and possessing the sulfonylurea bridge at the 2 position of the thiophene ring, exhibit high herbicidal activities on paddy field application.
Masahiko IKEGUCHI +3 more
openaire +3 more sources
Neonatal Diabetes Mellitus Due to KCNJ11 (KIR6.2) Mutation Successfully Treated with Sulfonylurea [PDF]
Neonatal diabetes mellitus (NDM) is a rare disease that occurs at less than 6 months of age and is presumably caused by a mutation in the gene that affects pancreatic beta-cell function. Approximately 80% of NDM cases reveal a known genetic mutation, and
Sehun Jang +5 more
doaj +1 more source

