Results 11 to 20 of about 10,498 (275)

Efficacy and Safety of Pioglitazone versus Glimepiride after Metformin and Alogliptin Combination Therapy: A Randomized, Open-Label, Multicenter, Parallel-Controlled Study [PDF]

open access: yesDiabetes & Metabolism Journal, 2020
BackgroundThere is limited information regarding the optimal third-line therapy for managing type 2 diabetes mellitus (T2DM) that is inadequately controlled using dual combination therapy.
Jeong Mi Kim   +12 more
doaj   +1 more source

Synthesis, Herbicidal Activity, Crop Safety and Soil Degradation of Pyrimidine- and Triazine-Substituted Chlorsulfuron Derivatives

open access: yesMolecules, 2022
Chlrosulfuron, a classical sulfonylurea herbicide that exhibits good safety for wheat but causes a certain degree of damage to subsequent corn in a wheat–corn rotation mode, has been suspended field application in China since 2014.
Lei Wu   +5 more
doaj   +1 more source

De novo HNF1A mutation of young maturity-onset diabetes 3 of a young girl—Case report

open access: yesBMC Endocrine Disorders, 2023
Young maturity-onset diabetes of the young type3(MODY3) as a special type of diabetes, the probability of diagnosis is low. This article reports on a case and reviews the relevant knowledge of the disease. We report an 11-year-and-11-month-old girl whose
Haoran Peng, Jianbo Li, Zhang Wang
doaj   +1 more source

The clinical aspects ot the sulphonylurea compounds from the position of the cardioprotective approach at patient with type 2 diabetes, using glucocardiomonitoring

open access: yesСахарный диабет, 2022
BACKGRAUND: Now the trend of Type 2 Diabetes Mellitus (T2DM) management from glucocentric to cardioprotective approach take place, and it especially relevant for the multiple group of patients with T2DM using Sulphonylurea (SU).
N. A. Chernikova   +3 more
doaj   +1 more source

Bioequivalence assessment of the two brands of glimepiride tablets [PDF]

open access: yesVojnosanitetski Pregled, 2006
Background/Aim. Glimepiride, as an antidiabetic from the group of sulfonylurea, is administered perorally in the treatment of diabetes mellitus. The aim of this study was to compare pharmacokinetic profiles and relative bioavailabilities of the two oral ...
Jovanović Dušan   +4 more
doaj   +1 more source

Synthesis of sulfonylurea derivatives and their α-glucosidase inhibitory activity

open access: yesVietnam Journal of Science, Technology and Engineering, 2022
The paper describes the preparation of new sulfonylurea derivatives from sulfonyl carbamate 6 with amino derivatives. The process for synthesis of the key compound 6 included three steps starting from compound 6-chloronicotinic acid 1, which are readily
Thi Thoi Bui   +2 more
doaj   +1 more source

Additional Effect of Dietary Fiber in Patients with Type 2 Diabetes Mellitus Using Metformin and Sulfonylurea: An Open-Label, Pilot Trial [PDF]

open access: yesDiabetes & Metabolism Journal, 2019
BackgroundMetformin, sulfonylurea, and dietary fiber are known to affect gut microbiota in patients with type 2 diabetes mellitus (T2DM). This open and single-arm pilot trial investigated the effects of the additional use of fiber on glycemic parameters,
Seung-Eun Lee   +7 more
doaj   +1 more source

Alkaline Soil Degradation and Crop Safety of 5-Substituted Chlorsulfuron Derivatives

open access: yesMolecules, 2022
Sulfonylurea herbicides can lead to serious weed resistance due to their long degradation times and large-scale applications. This is especially true for chlorsulfuron, a widely used acetolactate synthase inhibitor used around the world.
Lei Wu   +5 more
doaj   +1 more source

Novel Sulfonylurea Derivatives as Potential Antimicrobial Agents: Chemical Synthesis, Biological Evaluation, and Computational Study

open access: yesAntibiotics, 2023
Methicillin-resistant Staphylococcus aureus (MRSA) is a worldwide health threat and has already tormented humanity during its long history, creating an urgent need for the development of new classes of antibacterial agents.
Fan-Fei Meng   +8 more
doaj   +1 more source

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