Results 191 to 200 of about 1,586,161 (275)

Organelle‐Resolved Tetrazine‐trans‐Cyclooctene Click Chemistry for Cargo Delivery and Release

Chemistry – A European Journal, Volume 32, Issue 35, 19 September 2026.
Bioorthogonal click chemistry tools provide a means for specific intracellular conjugation of molecules. In this study, we used reactive tetrazine (Tz) and TCO moieties for labeling of organelles and organelle‐specific delivery and activation of doxorubicin prodrugs.
Oleh Durydivka, Marek Chovanec, Rastislav Dzijak, Michal Rahm, Jachym Hrusak, Paul E. Reyes‐Gutierrez, Milan Vrabel   +6 more
wiley   +1 more source

Five-year follow-up of incretin-based therapy in a patient with KCNJ11-related permanent neonatal diabetes: Achieving insulin discontinuation and sulfonylurea reduction. [PDF]

J Diabetes Investig
Ohkuma T, Aotani R, Sakamoto W, Oshiro A, Ago T.   +4 more
europepmc   +1 more source

The Impact of Polymers in Amorphous Solid Dispersion on the Bioavailability of Sulfonylureas and Meglitinides. [PDF]

Drug Des Devel Ther
Aulifa DL, Wibisono TTDW, Ningsih JD, Christy GDAB, Pertiwi DS, Praja HM, Gazzali AM, Amaliah S, Budiman A.   +8 more
europepmc   +1 more source

Screening of binding by antidiabetic drugs to normal vs AGE-modified human serum albumin through covalent immobilization and microscale affinity chromatography. [PDF]

J Chromatogr B Analyt Technol Biomed Life Sci
Woolfork AG, Rahman MM, Graham LM, Hage DS.   +3 more
europepmc   +1 more source

Influences of Fasting on Elimination of Sulfonylurea Compounds from Plasma in Rabbits

YAKUGAKU ZASSHI, 1983
S, Tsukiai, H, Fukuchi, M, Yoshida, M, Kumagai, T, Kitaura, S, Arai, N, Yata   +6 more
openaire   +3 more sources

Design, <i>in Vitro</i> Biological Activities and Molecular Dynamics Simulations of Novel Chalcone and Pyrazole Derivatives Targeting α‑Glucosidase and PPAR‑γ as Antidiabetic Agents. [PDF]

ACS Omega
Kurşun Aktar BS, Taşdemir D, Sağlam E, Kaya S, Yılmaz GT, Şahin Yağlioğlu A, Oruç-Emre EE.   +6 more
europepmc   +1 more source

Determination of Fluorinated Pesticide Residues and Their Selected Transformation Products in High-Water-Content Foods Using Complementary LC-MS/MS and GC-MS/MS Methods. [PDF]

Foods
Wenio I, Kwiatkowski D, Dawidziak DM, Derewiaka D, Majewska E, Bartosiewicz I.   +5 more
europepmc   +1 more source

Evaluation of %CV and average glucose derived from pre- and postprandial 6-point glucose measurements for assessing hypoglycemia risk. [PDF]

J Diabetes Investig
Soga R, Torimoto K, Uemura F, Okada Y, Nakayamada S.   +4 more
europepmc   +1 more source

Comparative safety of sulfonylurea therapies on cardiovascular and severe hypoglycemia outcomes among adults with type 2 diabetes and moderate cardiovascular risk: a target trial emulation. [PDF]

BMJ Open Diabetes Res Care
Sklepinski S, Ratzki-Leewing AA, Herrin J, Swarna KS, Deng Y, Polley EC, Neumiller JJ, Galindo RJ, Umpierrez GE, Ross JS, Brito JP, Montori VM, Borah BJ, Maron BA, Mickelson MM, McCoy RG.   +15 more
europepmc   +1 more source

Effectiveness of empagliflozin in reducing hypoglycemic events as compared to sulfonylurea in type 2 diabetes patients during fasting in Ramadan: a single-center study. [PDF]

BMC Endocr Disord
Kiran Z, Fatima N, Baloch AA, Shaikh KUS, Hasan SM, Khan MU.   +5 more
europepmc   +1 more source