Results 41 to 50 of about 5,240 (162)

Synthesis and oral hypoglycemic effect of novel thiazine containing trisubstituted benzenesulfonylurea derivatives

Saudi Pharmaceutical Journal, 2014
A new series of 3-(4-substituted phenyl)-1-(4-(4,6-dimethyl-6H-1,3-thiazin-2-yl)phenylsulfonyl)-1-substituted urea (5a–o) was synthesized by an effectual route via sulfonylcarbamates and explores the novel site for substitution in sulfonylurea as well as
Alok Singh Thakur, Ravitas Deshmukh, Arvind Kumar Jha, P. Sudhir Kumar   +3 more
doaj   +1 more source

Multifactorial wheat response under Fusarium culmorum, herbicidal, fungicidal and biostimulator treatments on the biochemical and mycotoxins status of wheat

Journal of the Saudi Society of Agricultural Sciences, 2021
A large-scale study under controlled conditions was conducted to estimate the influence of diversified level of biotic: Fusarium culmorum and abiotic factors: herbicide (H; sulfosulfuron), fungicides (F1; cyproconazole + propiconazole), (F2; spiroxamine +
Piotr Iwaniuk, Bozena Lozowicka, Piotr Kaczynski, Rafal Konecki   +3 more
doaj   +1 more source

Population attributable fraction of associated factors to adherence to blood glucose self-monitoring in diabetic type 2 patients treated with insulin or sulfonylureas/meglitinides: The results of DiaCare study in Iran

Journal of Education and Health Promotion
BACKGROUND: Self-monitoring of blood glucose (SMBG) is a part of diabetes management. Numerous investigations have demonstrated inadequate adherence to SMBG.
Amin Mohammadi, Gita Shafiee, Alireza Olyaeemanesh, Rajabali Daroudi, Amirhossein Aghakhani, Ensieh Nasli-Esfahani, Farideh Razi, Ramin Heshmat, Amirhossein Takian   +8 more
doaj   +1 more source

Mechanism of pharmacochaperoning in a mammalian KATP channel revealed by cryo-EM

eLife, 2019
ATP-sensitive potassium (KATP) channels composed of a pore-forming Kir6.2 potassium channel and a regulatory ABC transporter sulfonylurea receptor 1 (SUR1) regulate insulin secretion in pancreatic β-cells to maintain glucose homeostasis.
Gregory M Martin, Min Woo Sung, Zhongying Yang, Laura M Innes, Balamurugan Kandasamy, Larry L David, Craig Yoshioka, Show-Ling Shyng   +7 more
doaj   +1 more source

55P0110, a Novel Synthetic Compound Developed from a Plant Derived Backbone Structure, Shows Promising Anti-Hyperglycaemic Activity in Mice. [PDF]

PLoS ONE, 2015
Starting off with a structure derived from the natural compound multiflorine, a derivatisation program aimed at the discovery and initial characterisation of novel compounds with antidiabetic potential.
Barbara Brunmair, Zsuzsanna Lehner, Karin Stadlbauer, Immanuel Adorjan, Klaus Frobel, Thomas Scherer, Anton Luger, Leonhardt Bauer, Clemens Fürnsinn   +8 more
doaj   +1 more source

Study on the effect of electrochemical treatment of nicosulfuron wastewater

MATEC Web of Conferences, 2018
Nicosulfuron, a kind of sulfonylurea herbicide, because of its high activity and low dosage, has been widely used in corn planting weeding. Electrochemical method was chosen to treat its simulated waste water and the influence factors such as current ...
Zhao Rui, Jiang Wenqiang
doaj   +1 more source

Response of maize (Zea mays L.) to rimsulfuron under salt conditions

Acta Societatis Botanicorum Poloniae, 2011
Investigations were carried out to determine the possible interaction between salinity (60 mmol*dm-3 NaCl) and phytotoxicity of herbicide Titus 25 DF (sulfonylurea herbicide containing active ingredient rimsulfuron).
Elżbieta Sacała, Anna Demczuk, Tomasz Michalski   +2 more
doaj   +1 more source

Changes in the Activity and Selectivity of Herbicides by Selective Fluorine Substitution, Taking Bentranil and Classic® Analogues as Examples

CHIMIA, 2004
The introduction of fluorine atoms into 2-phenyl-4H-3,1-benzoxazin-4-one (bentranil) led to sweeping changes in its herbicidal properties in some cases, and 5-fluoro-2-phenyl-4H-3,1-benzoxazin-4-one ('fluorobentranil') was found to be the most ...
Gerhard Hamprecht, Bruno Würzer, Matthias Witschel   +2 more
doaj   +1 more source

Metabolomic insights into the intricate gut microbial–host interaction in the development of obesity and type 2 diabetes

Frontiers in Microbiology, 2015
Gut microbiota has recently been proposed as a crucial environmental factor in the development of metabolic diseases such as obesity and type 2 diabetes, mainly due to its contribution in the modulation of several processes including host energy ...
Magali ePalau-Rodriguez, Sara eTulipani, Sara eTulipani, MARIA ISABEL MI QUEIPO ORTUÑO, Mireia eUrpi-Sarda, Francisco J Tinahones, Cristina eAndres-Lacueva   +6 more
doaj   +1 more source

Recent Developments in Diabetes Management: Exploring Receptors, Pathways, and Compounds

BIO Integration
Diabetes mellitus (DM) is a widespread metabolic disorder with profound effects on vital organs. Often referred to as a “systemic” or “multi-organ” disorder due to the impact on key organs, such as the kidneys, pancreas, eyes, and heart, DM is ...
Pallavi Pandey, Vikash Jakhmola, Supriyo Saha, Anand Gaurav   +3 more
doaj   +1 more source