Results 141 to 150 of about 18,742 (250)

Long‐Term Glycemic and Metabolic Profiles Observed During Imeglimin Therapy in Japanese Patients With Type 2 Diabetes Mellitus

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 4, July 2026.
In a real‐world setting, 12‐month imeglimin therapy in Japanese patients with type 2 diabetes provided sustained glycemic improvements and enhanced endogenous insulin secretion. Importantly, these durable metabolic benefits were achieved without requiring an increase in overall glucose‐lowering treatment intensity.
Yohei Fujita, Shuji Suganami, Yuka Morita, Toshio Matsui, Masahisa Hata, Masahiro Hatazaki   +5 more
wiley   +1 more source

Comparative effects of second-line oral antidiabetic medications on atrial fibrillation risk in patients with type 2 diabetes: a nationwide retrospective cohort study. [PDF]

Cardiovasc Diabetol
Heo GY, Heo SJ, Ko B, Ko YE, Koh HB, Park CH, Park JT, Han SH, Yoo TH, Kang SW, Han M, Kim HW.   +11 more
europepmc   +1 more source

Sodium‐glucose cotransporter 2 inhibitors and the risk of late onset epilepsy: A real‐world cohort study

Epilepsia, Volume 67, Issue 7, Page 3444-3456, July 2026.
Abstract Objective Late onset epilepsy (LOE) is associated with substantial morbidity. Sodium‐glucose cotransporter 2 inhibitors (SGLT2i) may exert neuroprotective effects. This study evaluated the association between SGLT2i and risk of LOE among older adults with type 2 diabetes mellitus.
Bing‐Hua Lin, Hui‐Min Huang, Hui‐An Lin, Sheng‐Feng Lin   +3 more
wiley   +1 more source

Effectiveness of empagliflozin in reducing hypoglycemic events as compared to sulfonylurea in type 2 diabetes patients during fasting in Ramadan: a single-center study. [PDF]

BMC Endocr Disord
Kiran Z, Fatima N, Baloch AA, Shaikh KUS, Hasan SM, Khan MU.   +5 more
europepmc   +1 more source

Oleanolic Acid Ameliorates Hepatic Lipid Metabolism and Autophagy in Type 2 Diabetic Mice via the STAT3 Signaling Pathway

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
This study demonstrates that oleanolic acid (OA) may ameliorate type 2 diabetes mellitus (T2DM) by modulating hepatic lipid metabolism and autophagy in a manner concomitant with STAT3 phosphorylation. Specifically, OA downregulates fatty acid synthesis/uptake‐related proteins (SREBP‐1, ACC, CD36), upregulates fatty acid β‐oxidation‐related protein ...
Zirui Ji, Yuanfeng Huang, Xiangjin Pu, Jinqing Feng, Yiwen Liao, Wanfen Lin, Qing Zhu, Weixuan Wang   +7 more
wiley   +1 more source

Evaluation of potential approaches for counting person-time in instances where no active comparator is present. [PDF]

Am J Epidemiol
Giorgio K, Lutsey PL, Wang W, Walker R, Norby FL, Huling J.   +5 more
europepmc   +1 more source

Can a Lifestyle‐Centred, Low‐Dose Model Improve Hypertension and Diabetes Care in Low‐ and Middle‐Income Countries? Real‐World Implementation Data From Zambia

Lifestyle Medicine, Volume 7, Issue 3, July 2026.
ABSTRACT Introduction Hypertension and Type 2 diabetes are major contributors to the growing burden of non‐communicable diseases in rural Zambia. Lifestyle interventions are central to prevention and management, yet implementation remains limited in resource‐constrained settings.
Keith Birrell, Ginny Birrell, Fastone Goma   +2 more
wiley   +1 more source

Clinical Characteristics of Diabetic Cardiovascular Autonomic Neuropathy in Korean Individuals With Type 2 Diabetes

Journal of Diabetes, Volume 18, Issue 7, July 2026.
In long‐standing type 2 diabetes, cardiovascular autonomic neuropathy (CAN) was highly prevalent (88.4%), characterized by reduced heart rate variability (HRV) and prolonged QTc intervals. Advanced age and higher systolic pressure predicted CAN, indicating the importance of routine autonomic assessment and early blood pressure management, even with ...
Seon Mee Kang, Kyong Hye Joung, Chong Hwa Kim, Jae‐Seung Yun, Jong Chul Won, Jae Hyuk Lee, Chang Won Lee, Hyuk‐Sang Kwon, Ie Byung Park, Tae Sun Park   +9 more
wiley   +1 more source

Comparative Analysis of Clinical Outcomes in Patients With Type 2 Diabetes Mellitus on Monotherapy Versus Combination Therapy. [PDF]

Cureus
Mahapatra H, Gupta PK, Paul A, Nampalliwar A, Bansal M, Das B, Namboothiri KP.   +6 more
europepmc   +1 more source

A Systematic Review and Expert Evaluation of Perioperative SGLT2 Inhibitor‐Associated Ketoacidosis Case Reports

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 6, July 2026.
ABSTRACT Introduction The use of sodium–glucose cotransporter‐2 inhibitors (SGLT2i) in the perioperative setting may lead to SGLT2i‐associated postoperative ketoacidosis (SAPKA) in patients with type 2 diabetes (T2D). Therefore, cessation of this drug is recommended before surgery.
L. I. P. Snel, X. Li, F. Jamaludin, S. E. Siegelaar, F. Holleman, T. M. Vriesendorp, J. H. DeVries, J. B. L. Hoekstra, B. Preckel, D. H. van Raalte, J. Hermanides, A. H. Hulst   +11 more
wiley   +1 more source