Results 121 to 130 of about 7,003 (228)
Journal of Neuroscience Research, Volume 104, Issue 8, August 2026.Laboratory studies show KS has electroconductive properties with the ability to trap and transport protons in neurotransductive processes (Grotthuss proton shuttling). This maintains electrochemical gradients and fluxes at the neuronal cell surface in neural activation. Such processes are central to neuronal cell signaling and communication.
James Melrose
wiley +1 more source
Medications That Regulate Pregnane X Receptor: A Systematic Review of Current Evidence
Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.PRISMA 2020 flow diagram of study selection for this systematic review of medications that regulate the pregnane X receptor (PXR), from 12 236 records screened to 101 included studies. ABSTRACT The pregnane X receptor (PXR) gene encodes a ligand‐activated protein involved with the metabolism and excretion of drugs, toxins, and other xenobiotics.
Petra Czarniak +4 more
wiley +1 more source
Encounters With Traditional Medicine and Further Multidisciplinary and International Cooperation
Traditional &Kampo Medicine, Volume 13, Issue 2, August 2026.ABSTRACT Background The integration of traditional medicine (TM) into modern healthcare has gained global momentum. Following the inclusion of TM in the 11th revision of the International Classification of Diseases, multidisciplinary and international cooperation has become increasingly essential.
Kokoro Ichihara +6 more
wiley +1 more source
Beyond Sequence: Posttranslational Remodeling of Antigens in Autoimmunity
Immunological Reviews, Volume 341, Issue 1, August 2026.ABSTRACT Autoimmune responses are often attributed to failed tolerance to self‐proteins, yet protein expression alone cannot explain why certain antigens dominate disease, why autoreactivity emerges under stress, or why specific HLA alleles shape risk.
Cynthiya Shrestha +2 more
wiley +1 more source
Structure, function and regulation of human cytosolic sulfotransferases [PDF]
The sulfotransferase family of enzymes serve an important role in the metabolism of drugs and foreign chemicals. They also metabolise a range of chemicals that are normally present in the body such as hormones and substances that are involved in brain ...
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Characterisation of the sulfotransferases catalysing the sulfation of xenobiotics and steroids in bovine liver [PDF]
, 2011 Cattle are a very important part of the human food chain. Administration of veterinary drugs and other xenobiotic compounds to cattle can often result in the accumulation of metabolic residues in edible tissues that can potentially affect humans through ...
Choughule, Kanika
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Exploiting Substrate Specificities of 6‑O‑Sulfotransferases to Enzymatically Synthesize Keratan Sulfate Oligosaccharides [PDF]
Keratan sulfate (KS) is a glycosaminoglycan that is widely expressed in the extracellular matrix of various tissue types, where it is involved in many biological processes.
Yunfei Wu (322866) +7 more
core +1 more source
Nature CommunicationsHeparin is an important anticoagulant drug, and microbial heparin biosynthesis is a potential alternative to animal-derived heparin production. However, effectively using heparin synthesis enzymes faces challenges, especially with microbial recombinant ...
Jian-Qun Deng +8 more
doaj +1 more source
Characterization of human iodothyronine sulfotransferases [PDF]
, 1999 Sulfation is an important pathway of thyroid hormone metabolism that facilitates the degradation of the hormone by the type I iodothyronine deiodinase, but little is known about which human sulfotransferase isoenzymes are
Roest, T.J. (Thirza) +8 more
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Synergism of obesity genes with hepatic steroid sulfotransferases to mediate diabetes in mice. [PDF]
, 1991 Sulfotransferases controlling the intrahepatic ratio of actve obesity mutation will be diabetogenic in C57BL/KsJ female mice. Three unlinked genes (diabetes [db], obese [ob], and fat [fat]) all produced comparable obesity in C57BL/KsJ females, but ...
Falany, C N, Leiter, E H, Chapman, H D
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