Results 1 to 10 of about 322,242 (344)

Post-thaw dimethyl sulfoxide reduction in autologous peripheral blood progenitor cell suspensions [PDF]

Hematology, Transfusion and Cell Therapy
Background and objectives: Dimethyl sulfoxide has become the most common cryoprotectant used for cryopreservation of hematopoietic progenitor cells because of its efficiency, regardless of its potentially toxic side effects. Its application is considered
Miroslava Jandová, Pavel Měřička, Jiří Gregor, Miriam Lánská, Aleš Bezrouk, Dana Čížková, Jakub Radocha   +6 more
doaj   +2 more sources

The Oxidized Protein Repair Enzymes Methionine Sulfoxide Reductases and Their Roles in Protecting against Oxidative Stress, in Ageing and in Regulating Protein Function

Antioxidants, 2018
Cysteine and methionine residues are the amino acids most sensitive to oxidation by reactive oxygen species. However, in contrast to other amino acids, certain cysteine and methionine oxidation products can be reduced within proteins by dedicated ...
Sofia Lourenço dos Santos, Isabelle Petropoulos, Bertrand Friguet   +2 more
doaj   +2 more sources

The DmsABC Sulfoxide Reductase Supports Virulence in Non-typeable Haemophilus influenzae

Frontiers in Microbiology, 2021
Although molybdenum-containing enzymes are well-established as having a key role in bacterial respiration, it is increasingly recognized that some may also support bacterial virulence.
Rabeb Dhouib, Marufa Nasreen, Dk Seti Maimonah Pg Othman, Daniel Ellis, Simon Lee, Ama-Tawiah Essilfie, Philip M. Hansbro, Alastair G. McEwan, Ulrike Kappler   +8 more
doaj   +1 more source

2,5-[C₄+C₂] Ringtransformation of Pyrylium Salts with α-Sulfinylacetaldehydes

Molecules, 2023
A rapid synthesis of chiral sulfoxide-functionalized meta-terphenyl derivatives by a 2,5-[C4+C2] ring transformation reaction of pyrylium salts with in situ generated enantiomerically pure α-sulfinylacetaldehydes is described in this paper.
Dominik Bauer, Kathrin Hofmann, Michael Reggelin   +2 more
doaj   +1 more source

Dimethyl sulfoxide: a central player since the dawn of cryobiology, is efficacy balanced by toxicity?

Regenerative medicine, 2020
Dimethyl sulfoxide (DMSO) is the cryoprotectant of choice for most animal cell systems since the early history of cryopreservation. It has been used for decades in many thousands of cell transplants.
Maooz Awan, I. Buriak, R. Fleck, B. Fuller, A. Goltsev, Julie E Kerby, M. Lowdell, P. Měřička, A. Petrenko, Y. Petrenko, A. Stolzing, O. Rogulska, G. Stacey   +12 more
semanticscholar   +1 more source

Synthesis of Polysubstituted Ferrocenesulfoxides

Molecules, 2022
The purpose of the study is to design synthetic methodologies, especially directed deprotometalation using polar organometallic reagents, to access polysubstituted ferrocenesulfoxides.
Min Wen, William Erb, Florence Mongin, Yury S. Halauko, Oleg A. Ivashkevich, Vadim E. Matulis, Thierry Roisnel   +6 more
doaj   +1 more source

Study on Autocatalytic Decomposition of Dimethyl Sulfoxide (DMSO)

Organic Process Research & Development, 2020
Dimethyl sulfoxide (DMSO) is widely used due to its excellent solvent properties; however, several serious incidents have been reported related to the use of DMSO.
Y. Deguchi, M. Kono, Yuto Koizumi, Y. Izato, A. Miyake   +4 more
semanticscholar   +1 more source

Photoredox Catalytic Trifluoromethylation and Perfluoroalkylation of Arenes Using Trifluoroacetic and Related Carboxylic Acids

Cell Reports Physical Science, 2020
Summary: Trifluoroacetic acid (TFA) is among the most attractive trifluoromethylation reagents with respect to its low prices, ease of handling, and availability in large quantities.
Dehang Yin, Dengquan Su, Jian Jin
doaj   +1 more source

Effective Oxidation of Sulfides to Sulfoxides with Hydrogen Peroxide under Transition-Metal-Free Conditions

Molecules, 2007
A “green” highly selective oxidation of organic sulfides to the corresponding sulfoxides was developed using hydrogen peroxide and glacial acetic acid under transition metal-free and mild conditions.
Farideh Hosseinpoor, Hamid Golchoubian
doaj   +1 more source

N-Methyl-(R)-3-(tert-Butyl)-Sulfinyl-1,4-Dihydropyridine: A Novel NADH Model Compound

Molecules, 2007
We have synthesized a novel chiral NADH model compound, N-methyl-(R)-3-(tert-butyl)-sulphinyl-1,4-dihydropyridine with high enantioselectivity and used it in the reduction of methyl benzoylformate, producing (S)-methyl mandelate in 95% ee.
Thomas CW Mak, Yao Fu, Jian-Ge Wang, Yi Cui, You-Cheng Liu, Kun Xie   +5 more
doaj   +1 more source