Results 21 to 30 of about 322,242 (344)
A pH-dependence of the Brønsted acid-catalyzed oxidation of sulfides to the corresponding sulfoxides with H2O2 is reported for the first time based on our systematic investigation of the catalytic performance of a series of Brønsted acids. For all of the
Hai-Min Shen +8 more
doaj +1 more source
With the development of antimicrobial agents, researchers have developed new strategies through key regulatory systems to block the expression of virulence genes without affecting bacterial growth.
Xinyi Ye +5 more
doaj +1 more source
The purpose of the research is to study the biotransformation of fenbendazole in the body of sheep after administration of fenbendazole solid dispersion (FSD) prepared by mechanochemical technique with arabinogalactan. Materials and methods. The FSD at a
I. A. Arkhipov +3 more
doaj +1 more source
Hypoglycemic and hypolipidemic effect of S-allyl-cysteine sulfoxide (alliin) in DIO mice
Alliin (S-allyl cysteine sulfoxide) is a bioactive sulfoxide compound derived from garlic. To evaluate the preventive effect of alliin against metabolic risk factors in diet induced obese (DIO) mice, we treated the C57BL/6J DIO mice with drinking water ...
Baiqiang Zhai +7 more
semanticscholar +1 more source
Inhibition of methionine sulfoxide reduction by dimethyl sulfoxide
Dimethyl sulfoxide (DMSO) is widely used in chemistry and biology as a solvent and as a cryoprotectant. It is also used as a pharmaceutical agent for the treatment of interstitial cystitis and rheumatoid arthritis. Previous reports described DMSO as being reduced by methionine-S-sulfoxide reductase (MsrA).
Kim +3 more
openaire +4 more sources
Thiol-free chemoenzymatic synthesis of β-ketosulfides
A preparation of β-ketosulfides avoiding the use of thiols is described. The combination of a multicomponent reaction and a lipase-catalysed hydrolysis has been developed in order to obtain high chemical diversity employing a single sulfur donor.
Adrián A. Heredia +4 more
doaj +1 more source
Synthesis and Evaluation of Novel Benzofuran Derivatives as Selective SIRT2 Inhibitors
A series of benzofuran derivatives were designed and synthesized, and their inhibitory activites were measured against the SIRT1–3. The enzymatic assay showed that all the compounds showed certain anti-SIRT2 activity and selective over SIRT1 and SIRT3 ...
Yumei Zhou +10 more
doaj +1 more source
Adverse reactions of dimethyl sulfoxide in humans: a systematic review
Background: Dimethyl sulfoxide (DMSO) has been used for medical treatment and as a pharmacological agent in humans since the 1960s. Today, DMSO is used mostly for cryopreservation of stem cells, treatment of interstitial cystitis, and as a penetrating ...
Bennedikte Kollerup Madsen +3 more
semanticscholar +1 more source
Background Methionine sulfoxide reductases are found in all aerobic organisms. They function in antioxidant defense, cellular regulation by reversible oxidation of methionine in proteins, and in protein structure.
Sujin Park +2 more
doaj +1 more source
Sulfoxides. V. The Ionization of Sulfoxides in Sulfuric Acid [PDF]
Abstract Contrary to the earlier claim that diphenyl sulfoxide ionizes in nearly 100% sulfuric acid to give a “diphenyl sulfidonium” ion, which can then return to the original sulfoxide when quenched with water, the 18O tracer experiment and a new set of cryoscopic determinations of a few sulfoxides have revealed that the dissociation of
Shigeru Oae +2 more
openaire +2 more sources

