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Azide-functionalized SpCas9 enables generation of site-selective and bioactive Cas9-siRNA conjugates.

open access: yesChem Commun (Camb)
Wilbie D   +9 more
europepmc   +1 more source

Role of Astrocytes in Central Respiratory Control. [PDF]

open access: yesCells
Okada Y   +6 more
europepmc   +1 more source
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Syntheses and Transformations of Sulfoximines

The Chemical Record, 2020
Abstract Sulfoximines are widely used as medicines, agricultural chemicals, chiral precursors, and chiral ligands in asymmetric synthesis, as well as pivotal intermediates for the construction of heterocyclic compounds. NH‐sulfoximines may be synthesized from thioethers, sulfoxides, sulfilimines, and sulfinamides.
Wenting Zheng   +4 more
openaire   +2 more sources

The N-silylation of sulfoximines

Organic & Biomolecular Chemistry, 2015
The copper-catalyzed N -silylation of sulfoximines was achieved in good to moderate yields in the presence of di- tert -butyl peroxide.
Haibo, Peng   +4 more
openaire   +2 more sources

Halocyclizations of Unsaturated Sulfoximines

Organic Letters, 2016
A method for halocyclizations of S-alkenylsulfoximines is reported. When unsaturated NH-sulfoximines are treated with a combination of iodobenzene diacetate and potassium iodide, a transformation to the corresponding five- and six-membered cyclic products occurs providing S-oxides of dihydro isothiazoles and tetrahydro-1,2-thiazines, respectively, in ...
Han, Wang, Marcus, Frings, Carsten, Bolm
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Sulfoximines in pseudopeptides

Tetrahedron Letters, 1997
Abstract Syntheses of sulfoximine-containing pseudopeptides of type 2 are reported. Intramolecular hydrogen bonds have been revealed by NMR spectroscopy.
Carsten Bolm, Jan D. Kahmann, Guido Moll
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The metabolism of methionine sulfoximine

Archives of Biochemistry and Biophysics, 1954
Abstract A single dose of l -methionine sulfoximine-S 35 was injected into rats and the distribution of S 35 determined in the various sulfur fractions of the urine at 24 hour intervals for 5 days. The amount of S 35 as sulfate increased from 5 % the first day to 32 % the fifth.
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The Methionine Sulfoximine Syndrome in the Cat

Epilepsia, 1962
SUMMARYMethionine sulfoximine, the toxic principle of the agenized protein diet, produces in the cat a complex syndrome characterized by behavioral and convulsive changes. In a series of 50 cats, the following features were most consistently observed:Sniffing movements, involving the upper lip, nose and lower eyelid, and accompanied by profuse ...
M, PROLER, P, KELLAWAY
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