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Synthesis and Transformations of NH-Sulfoximines [PDF]

open access: yesChemistry - A European Journal, 2021
Abstract Recent years have seen a marked increase in the occurrence of sulfoximines in the chemical sciences, often presented as valuable motifs for medicinal chemistry. This has been prompted by both pioneering works taking sulfoximine containing compounds into clinical trials and the concurrent development of powerful synthetic ...
Leonardo Degennaro   +2 more
exaly   +6 more sources
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Syntheses and Transformations of Sulfoximines

The Chemical Record, 2020
Abstract Sulfoximines are widely used as medicines, agricultural chemicals, chiral precursors, and chiral ligands in asymmetric synthesis, as well as pivotal intermediates for the construction of heterocyclic compounds. NH‐sulfoximines may be synthesized from thioethers, sulfoxides, sulfilimines, and sulfinamides.
Wenting Zheng   +4 more
openaire   +2 more sources

Difluoromethyl and Chlorofluoromethyl Sulfoximines: Synthesis and Evaluation as Electrophilic Perfluoroalkylating Reagents

open access: yesEuropean Journal of Organic Chemistry, 2015
International audienceAn efficient and convenient method is described that allows the synthesis of a set of difluoromethyl sulfoximines, as well as chlorofluoromethyl sulfoxides, sulfones, and sulfoximines.
Bruce Pégot   +2 more
exaly   +2 more sources

The N-silylation of sulfoximines

Organic & Biomolecular Chemistry, 2015
The copper-catalyzed N -silylation of sulfoximines was achieved in good to moderate yields in the presence of di- tert -butyl peroxide.
Haibo, Peng   +4 more
openaire   +2 more sources

Copper-Catalyzed Oxidative Cross-Coupling of Sulfoximines and Alkynes

open access: yesAngewandte Chemie - International Edition, 2013
Copper-catalyzed oxidative cross-coupling of sulfoximines and ...
Carsten Bolm, Daniel L. Priebbenow
exaly   +1 more source

Halocyclizations of Unsaturated Sulfoximines

Organic Letters, 2016
A method for halocyclizations of S-alkenylsulfoximines is reported. When unsaturated NH-sulfoximines are treated with a combination of iodobenzene diacetate and potassium iodide, a transformation to the corresponding five- and six-membered cyclic products occurs providing S-oxides of dihydro isothiazoles and tetrahydro-1,2-thiazines, respectively, in ...
Han, Wang, Marcus, Frings, Carsten, Bolm
openaire   +2 more sources

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