Results 151 to 160 of about 1,705 (200)

Sulfoximines in pseudopeptides

Tetrahedron Letters, 1997
Abstract Syntheses of sulfoximine-containing pseudopeptides of type 2 are reported. Intramolecular hydrogen bonds have been revealed by NMR spectroscopy.
Carsten Bolm, Jan D. Kahmann, Guido Moll
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The metabolism of methionine sulfoximine

Archives of Biochemistry and Biophysics, 1954
Abstract A single dose of l -methionine sulfoximine-S 35 was injected into rats and the distribution of S 35 determined in the various sulfur fractions of the urine at 24 hour intervals for 5 days. The amount of S 35 as sulfate increased from 5 % the first day to 32 % the fifth.
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The Methionine Sulfoximine Syndrome in the Cat

Epilepsia, 1962
SUMMARYMethionine sulfoximine, the toxic principle of the agenized protein diet, produces in the cat a complex syndrome characterized by behavioral and convulsive changes. In a series of 50 cats, the following features were most consistently observed:Sniffing movements, involving the upper lip, nose and lower eyelid, and accompanied by profuse ...
M, PROLER, P, KELLAWAY
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Sulfones and Sulfoximines

1977
Sulfones are compounds in which the sulfur atom is bonded to two carbon atoms and two terminal oxygens in a tetrahedral arrangement, which is easily deformable.1 The sulfonyl moiety probably is a hydrid of the forms shown below ...
William E. Truce, Thomas C. Klingler, William W. Brand   +2 more
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Chemosensitization by buthionine sulfoximine in vivo

International Journal of Radiation Oncology*Biology*Physics, 1986
The in vivo effects of buthionine sulfoximine (BSO), an inhibitor of glutathione (GSH) biosynthesis, on the cytotoxicity of cyclophosphamide (CYM), cisplatin (CDDP) and bleomycin (BLM), were examined by monitoring the changes of non-protein thiols (NPSH) in normal tissues and in the NFSa fibrosarcoma. We used the lung colony assay as a measure of tumor
K, Tsutsui, C, Komuro, K, Ono, T, Nishidai, Y, Shibamoto, M, Takahashi, M, Abe   +6 more
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Amino acid sulfoximines: α-Ethylmethionine sulfoximine

1987
Publisher Summary Several procedures for the synthesis of sulfoximines, also known as “sulfoximides” are reported, amino acid sulfoximines are nearly always synthesized by treatment of the corresponding sulfide or sulfoxide with hydrazoic acid. The procedure does not racemize α-amino acids but does yield an R , S mixture at the suifoximine sulfur;
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A convenient synthesis of vinyl sulfoximines from β-hydroxyalkyl sulfoximines

Tetrahedron Letters, 1987
Abstract Previously unknown free and N-acylated vinyl sulfoximines were readily prepared via elimination of β-hydroxyalkyl methylphenylsulfoximines.
Ki-Jun Hwang, Eugene W. Logusch
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Ammonia and methionine sulfoximine intoxication

Brain Research, 1982
Intoxication with ammonium acetate abolished the suppression of action potential generation by cortical postsynaptic inhibition, i.e. produced 'disinhibition', due to the inactivation of neuronal Cl- extrusion. With the occurrence of disinhibition cerebral ammonia increased to 445% of normal; glutamine increased to 170%.
W A, Raabe, G R, Onstad
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Organocatalytic Kinetic Resolution of Sulfoximines

Journal of the American Chemical Society, 2016
An efficient kinetic resolution of sulfoximines with enals was realized using chiral N-heterocyclic carbene (NHC) catalysts. The stereoselective amidation proceeds without additional acyl transfer agent. Both enantiomers of the sulfoximines can be obtained with excellent ee values (up to 99% ee and -97% ee, respectively).
Shunxi, Dong, Marcus, Frings, Hanchao, Cheng, Jian, Wen, Duo, Zhang, Gerhard, Raabe, Carsten, Bolm   +6 more
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Conversion and degradation pathways of sulfoximines

Chemical Society Reviews, 2019
The overview describes laboratory transformations leading to sulfoximine degradations to enable more focussed analyses of potential products and pathways.
Stefan Wiezorek, Philip Lamers, Carsten Bolm   +2 more
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