Results 71 to 80 of about 1,705 (200)
Natural Product‐Induced Ferroptosis to Overcome Therapy Resistance in Aggressive Cancers
ChemMedChem, Volume 21, Issue 20, 28 October 2026.Natural products trigger ferroptosis through iron overload, glutathione depletion, glutathione peroxidase 4 inhibition, and reactive oxygen species accumulation, selectively targeting aggressive, and drug‐resistant cancers. Polyphenols, alkaloids and terpenoids emerge as promising multi‐target agents to overcome therapy resistance and improve future ...
Giorgio Antoniolli
wiley +1 more source
Organoboron/Palladium Co-Catalytic Allylation of NH-Sulfoximines using Allylic Alcohols [PDF]
Sulfoximines have been widely recognized as an important functional group in drug discovery and medicinal chemistry, and have significant uses in pharmaceuticals, agrochemicals, materials, and organic synthesis.
Ho, Celine Yin Yung
core +1 more source
Angewandte Chemie, Volume 138, Issue 41, 5 October 2026.Modular access to underexplored C5‐sulfenyl thiazoles via an intermolecular Pummerer rearrangement is reported. The methodology exhibits a broad functional group tolerance enabling the seamless design of trisubstituted thiazole cores bearing a sulfur handle for further elaboration.
Joe L. Smy +5 more
wiley +1 more source
Catalytic synthesis of chiral sulfinimidate esters via oxidative esterification of sulfenamides
Nature CommunicationsAza-sulfur compounds, such as sulfilimines, sulfoximines, etc, are increasingly recognized as essential contributors to advancements in drug development and asymmetric synthesis.
Hua-Jie Jiang +8 more
doaj +1 more source
Bicyclo[1.1.1]pentyl Sulfoximines: Synthesis and Functionalizations [PDF]
, 2020 Herein we present the first synthesis of bicyclo[1.1.1]pentyl (BCP) sulfoximines from the corresponding sulfides. Both BCPs and sulfoximines are bioisosteres used in medicinal chemistry and therefore desirable motifs.
Nieger, Martin +7 more
core +1 more source
Photochemical nitrene transfer reactions of iminoiodinanes with sulfoxides
Green Synthesis and CatalysisNitrene, as an important and intriguing versatile synthon, is widely utilized for the formation of diverse nitrogenous skeletons under thermal or photochemical conditions. Typically, the N-sulfonyl nitrenes could be smoothly generated from iminoiodinanes
Xuemei Zhao +5 more
doaj +1 more source
A Mild and Efficient Procedure for the N-Functionalization of S-Perfluoroalkylated Aryl Sulfoximines
, 2013 International audienceN-Acylated perfluoroalkylated sulfoximines are synthesized easily from the corresponding free NH-sulfoximines on reaction with acid chlorides.
Pégot, Bruce +8 more
core +1 more source
ChemistryEuropeC─H functionalization presents opportunities to streamline the synthesis of valuable molecular structures. This study details the development of a copper‐mediated, transient C(sp2)–H sulfanylation of benzylamines with a transient directing group (TDG ...
Tsz‐Kan Ma +4 more
doaj +1 more source
Visible-Light-Induced One-Pot Cross Coupling of NH-Sulfoximines with Toluene
A one-pot cross-coupling reaction of NH-sulfoximines with toluene was realized by visible light-induced catalysis. The relatively inert toluene and sulfoximines were activated under mild conditions, and the functionalized sulfoximines were obtained via ...
Qiumei Su (14076097) +3 more
core +1 more source
NH‐Sulfilimine Synthesis Catalyzed by Nonheme Iron(II) Complex
ChemistryEuropeIron‐catalyzed nitrene transfer reactions have gained significant interest in recent decades. However, the catalytic synthesis of sulfilimines, the aza‐analog of sulfoxides, remains underexplored, and the few examples published only describe protected ...
Léa Tesson +2 more
doaj +1 more source