Results 51 to 60 of about 1,705 (200)
Biotechnology and Bioengineering, EarlyView.ABSTRACT The glutamine synthetase expression system is widely used for therapeutic protein biomanufacturing in Chinese hamster ovary (CHO) cells. Here, we present the design of an enhanced glutamine synthetase vector for generating CHOK1SV GS‐KO stable pools that produce recombinant proteins at multigram‐per‐liter levels. We first developed a synthetic
Yusuf B. Johari +11 more
wiley +1 more source
C─S Bond Formation of Aryl Germanes
Angewandte Chemie, Volume 138, Issue 41, 5 October 2026.Site‐selective C─S bond formation of aryl germanes, even in the presences of other functional groups such as silane or boron derivatives, is described. The protocol operates under metal‐free conditions at room temperature without the need of inert atmosphere.
Jaime Ponce‐de‐León +6 more
wiley +2 more sources
Ecotoxicology and Environmental Safety, 2021 Flupyradifurone, a novel butenolide insecticide, selectively targets insect nicotinic acetylcholine receptors (nAChRs), comparable to structurally different insecticidal chemotypes such as neonicotinoids and sulfoximines.
Julian Haas +11 more
doaj +1 more source
Biomimetic N‐cyano sulfoximine–thiazole ligation for antibody–drug conjugate assembly
Bulletin of the Korean Chemical Society, EarlyView.Biomimetic N‐cyano sulfoximine–thiazole ligation is applied for the first time to antibody–drug conjugate assembly. Installation of a sulfoximine handle on trastuzumab followed by ligation with a cysteine‐functionalized payload affords model ADCs with tunable drug‐to‐antibody ratios of 2–8 under mild aqueous conditions.
Eunsil Kim +7 more
wiley +1 more source
European Journal of Organic Chemistry, EarlyView.The nickel‐catalyzed S═NH N‐arylation of sulfonimidamides is described, with useful demonstrated substrate scope involving inexpensive and widely available (hetero)aryl chloride reaction partners, including the active pharmaceutical ingredient chlorpromazine.
Samuel A. Fisher +2 more
wiley +1 more source
Photochemistry of N‐Phenyl Benzonaphthothiophene and Dinaphthothiophene Sulfoximines
European Journal of Organic Chemistry, EarlyView.The sequential photorelease of nitrenes and atomic oxygen [O(3P)] from N‑phenyl benzonaphthothiophene and dinaphthothiophene sulfoximines is a rare photochemical phenomenon in which two reactive intermediates can be released from a single chromophore. The sequential photorelease of nitrenes and atomic oxygen [O(3P)] is a rare photochemical phenomenon ...
Henry J. Politte +3 more
wiley +1 more source
Synthesis and Computational Simulation of New Phosphorilated Sulfoximines with Insecticidal Activity
Molecules, 2000 New organophosphorus insecticides of dialkylsulphoximines derived with activity upon acetylcholinesterase were synthesized. The obtained compounds were characterized by NMR and IR, and anticholinesterase activity and toxicity was measured.
S. A. Licastrode +1 more
doaj +1 more source
Copper-Mediated Cross-Coupling Reactions of N-Unsubstituted Sulfoximines and Aryl Halides
, 2016 Copper-mediated cross-coupling reactions of sulfoximines with aryl iodides and aryl bromides provide N-arylated sulfoximines in high yields. The method is complementary to the known palladium-catalyzed N-arylation and allows the preparation of N-arylated
Jenny Jansson (2707951) +4 more
core +1 more source
Functionalizations of sulfoximines and mechanochemistry studies
, 2022 Sulfoximines, the mono-aza analogs of sulfones, have attracted the attention of many chemists in the last few decades. Since the first discovery of MSO. Sulfoximines have been extensively used in agricultural science, asymmetric synthesis, and medicinal ...
Shi, Peng
core +1 more source
Pest Management Science, EarlyView.Monitoring of Euschistus heros populations in Rio Grande do Sul, Brazil, from 2017 to 2026 revealed declining susceptibility to pyrethroids and neonicotinoids. Reduced susceptibility to λ‐cyhalothrin and acetamiprid persisted, whereas declines in susceptibility to bifenthrin, imidacloprid and certain pre‐formulated mixtures emerged more recently ...
Luiz F Warpechowski +7 more
wiley +1 more source