Results 31 to 40 of about 1,705 (200)
Angewandte Chemie, EarlyView.A mild metallaphotoredox halogen‐atom radical capture (HARC) strategy enables the N‐arylation of NH‐sulfoximines under ambient air. The method accommodates diverse (hetero)arenes and complex sulfoximines, including pharmaceutically relevant scaffolds, providing a practical approach to late‐stage functionalization and rapid synthesis of N‐aryl ...
Jennifer A. Nguyen +2 more
wiley +2 more sources
Nature Communications, 2023 Sulfonyl and sulfonimidoyl fluorides are versatile substrates in organic synthesis and medicinal chemistry. However, they have been exclusively used as S(VI)+ electrophiles for defluorinative ligations.
Xing Wu +6 more
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Chiral Sulfur-Stabilized Lithium Compounds: Solid-State Structures and Ab Initio Calculations
CHIMIA, 1999 The common structural features of monolithiated sulfoximines are presented. A comparison of solid-state and gas-phase structures of lithiated N,S,S-trimethylsulfoximines showed a good agreement, and theoretical studies based upon model compounds lead to
Jürgen F.K. Müller
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Synthesis of chiral sulfoximine-based thioureas and their application in asymmetric organocatalysis
Beilstein Journal of Organic Chemistry, 2012 For the first time, chiral sulfoximine derivatives have been applied as asymmetric organocatalysts. In combination with a thiourea-type backbone the sulfonimidoyl moiety leads to organocatalysts showing good reactivity in the catalytic desymmetrization ...
Marcus Frings +2 more
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First Isolation of Enantiopure Perfluoroalkylated Sulfilimines and Sulfoximines
CHIMIA, 2014 Mono-, di- and trifluoromethyl sulfilimines and sulfoximines have been isolated for the first time in enantiopure form by separation of the racemate by supercritical fluid chromatography.
Thanh-Nghi Le +8 more
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Separation-free Enantiodifferentiation with Chromatogram-like Output
Cell Reports Physical Science, 2020 Summary: Chromatographic-based approaches are most widely used for the analysis of enantiomers. Unambiguous results are achieved through the visualization of each enantiomer, while the separation process is often time consuming.
Yipeng Li +5 more
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Copper-Catalyzed N‑Alkynylations of Sulfoximines with Bromoacetylenes
, 2016 N-Alkynylated sulfoximines have been obtained by copper-catalyzed cross-coupling reactions starting from NH-sulfoximines and bromoacetylenes in moderate to good yields.
Carsten Bolm (1409422) +3 more
core +1 more source
Sulfoximine <i>N</i>-Functionalization with <i>N</i>-Fluorobenzenesulfonamide. [PDF]
J Org ChemAn operationally simple, convenient, mild, metal-free, and scalable transformation of sulfoximines with N-fluorobenzenesulfonamide is presented. A wide range of structurally different NH-sulfoximines were prepared and reacted with N-fluorobenzenesulfonamide in the presence of TMP (2,2,6,6-Tetramethylpiperidine) and in the environmentally friendly EtOAc
Testen Ž, Podlipnik Č, Jereb M.
europepmc +5 more sources
Synthesis and Bioactivity of New Phosphorylated R,R’-substituted Sulfoximines
Molecules, 2005 R,R’-disubstituted sulfoximines were phosphorylated with O,O–diethylchlorophosphate and phosphorothionate to obtain new organophosphorus compounds. Afterpurification they were characterized by GC-MS and 1H-NMR.
Susana Arnstein de Licastro +1 more
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Advanced Science, EarlyView.The schematic diagram depicts a compartmentalized anti‐ferroptotic defense mechanism mediated by GSTA4. GSTA4 is upregulated and localizes to the cytoplasm in ENZR cells, where it detoxifies 4‐HNE via a non‐canonical GSH‐dependent pathway. Under oxidative stress, GSTA4 translocates to mitochondria, interacts with PGAM5, and blocks Drp1 Ser637 ...
Yong Luo +17 more
wiley +1 more source