Results 1 to 10 of about 2,387 (211)

Multidirectional Changes in Parameters related to Sulfur Metabolism in Frog Tissues exposed to Heavy Metal-related Stress. [PDF]

Biomolecules, 2020
The investigations showed changes of the cystathionine $\gamma$ -lyase (CTH), 3-mercaptopyruvate sulfurtransferase (MPST) and rhodanese (TST) activity and gene expression in the brain, heart, liver, kidney, skeletal muscles and testes in frogs Pelophylax
Kaczor-Kamińska M, Sura P, Wróbel M.
europepmc   +6 more sources

Catalytic Site Cysteines of Thiol Enzyme: Sulfurtransferases [PDF]

Journal of Amino Acids, 2011
Thiol enzymes have single- or double-catalytic site cysteine residues and are redox active. Oxidoreductases and isomerases contain double-catalytic site cysteine residues, which are oxidized to a disulfide via a sulfenyl intermediate and reduced to a ...
Nagahara, Noriyuki
core   +8 more sources

Dimethyl Sulfoxide (DMSO) as a Potential Source of Interference in Research Related to Sulfur Metabolism-A Preliminary Study. [PDF]

Antioxidants (Basel)
Dimethyl sulfoxide (DMSO), an organosulfur compound, is widely used as the gold standard solvent in biological research. It is used in cell culture experiments and as a component of formulations in in vivo studies.
Kaczor-Kamińska M, Kaszuba K, Bilska-Wilkosz A, Iciek M, Wróbel M, Kamiński K.   +5 more
europepmc   +5 more sources

Unraveling the role of thiosulfate sulfurtransferase in metabolic diseases [PDF]

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2020
Thiosulfate sulfurtransferase (TST, EC 2.8.1.1), also known as Rhodanese, is a mitochondrial enzyme which catalyzes the transfer of sulfur in several molecular pathways.
Aguilar Lozano, Sheila P, Al-Dahmani, Zayana M, de Assis Batista, Fernando, Dolga, Amalia M, Groves, Matthew R, Joles, Jaap A, Kruithof, Paul D, Lunev, Sergey, van Goor, Harry   +8 more
core   +5 more sources

Possible molecular basis of the biochemical effects of cysteine-derived persulfides. [PDF]

Front Mol Biosci, 2022
Persulfides (RSSH/RSS−) are species closely related to thiols (RSH/RS−) and hydrogen sulfide (H2S/HS−), and can be formed in biological systems in both low and high molecular weight cysteine-containing compounds.
Cuevasanta E, Benchoam D, Semelak JA, Möller MN, Zeida A, Trujillo M, Alvarez B, Estrin DA.   +7 more
europepmc   +4 more sources

Transcriptomics of the <i>Anthopleura</i> Sea Anemone Reveals Unique Adaptive Strategies to Shallow-Water Hydrothermal Vent. [PDF]

Ecol Evol
The nonsymbiotic sea anemone Anthopleura nigrescens thrives in the extreme shallow‐water hydrothermal vents off Kueishan Island, Taiwan, where they represent some of the world's most extreme environments. Transcriptomic analyses revealed that genes involved in H2S homeostasis, stress resistance, and DNA repair are enriched in vent populations ...
Lin MF, Liu LL, Chen CA.
europepmc   +2 more sources

Structural and biochemical characterization of an encapsulin-associated rhodanese from Acinetobacter baumannii. [PDF]

Protein Sci
Abstract Rhodanese‐like domains (RLDs) represent a widespread protein family canonically involved in sulfur transfer reactions between diverse donor and acceptor molecules. RLDs mediate these transsulfuration reactions via a transient persulfide intermediate, created by modifying a conserved cysteine residue in their active sites.
Benisch R, Giessen TW.
europepmc   +2 more sources

Investigation of the role of sulfurtransferases in the metabolism of higher plants [PDF]

, 2013
[no ...
Henne, Melina
core   +4 more sources

NRF2 signalling in cytoprotection and metabolism

British Journal of Pharmacology, EarlyView., 2023
The KEAP1‐NRF2 system plays a central role in cytoprotection in defence mechanisms against oxidative stress. The KEAP1‐NRF2 system has been regarded as a sulfur‐utilizing cytoprotective mechanism, because KEAP1 serves as a biosensor for electrophiles by using its reactive thiols and NRF2 is a transcriptional factor regulating genes involved in sulfur ...
Shohei Murakami, Yusuke Kusano, Keito Okazaki, Takaaki Akaike, Hozumi Motohashi   +4 more
wiley   +1 more source

Supersulfide biology and translational medicine for disease control

British Journal of Pharmacology, EarlyView., 2023
Abstract For decades, the major focus of redox biology has been oxygen, the most abundant element on Earth. Molecular oxygen functions as the final electron acceptor in the mitochondrial respiratory chain, contributing to energy production in aerobic organisms. In addition, oxygen‐derived reactive oxygen species including hydrogen peroxide and nitrogen
Uladzimir Barayeu, Tomohiro Sawa, Motohiro Nishida, Fan‐Yan Wei, Hozumi Motohashi, Takaaki Akaike   +5 more
wiley   +1 more source