Results 51 to 60 of about 1,145 (168)
The Concise Guide to PHARMACOLOGY 2025/26: Enzymes
British Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +31 more
wiley +1 more source
The effect of lipoic acid on cyanate toxicity in different structures of the rat brain [PDF]
, 2013 Cyanate is formed mostly during nonenzymatic urea biodegradation. Its active form isocyanate reacts with protein –NH(2) and –SH groups, which changes their structure and function. The present studies aimed to investigate the effect of cyanate on activity
Bilska-Wilkosz, Anna +3 more
core +1 more source
Expression of 3-Mercaptopyruvate Sulfurtransferase in the Mouse [PDF]
Molecules, 2016 3-Mercaptopyruvate sulfurtransferase (MST) is one of the principal enzymes for the production of hydrogen sulfide and polysulfides in mammalians, and emerging evidence supports the physiological significance of MST. As a fundamental study of the physiology and pathobiology of MST, it is necessary to establish the tissue distribution of MST in mice.
Masahiro Tomita +2 more
openaire +3 more sources
Physiological Reports, Volume 13, Issue 24, December 2025.Abstract Perivascular adipose tissue (PVAT) regulates vascular tone, and high‐fat diets reportedly lead to the loss of its anti‐contractile properties. Methionine restriction recapitulates many caloric restriction metabolic effects and increases liver expression of activating transcription factor 4 (ATF4) and downstream targets with anti‐contractile ...
Adam Corken +4 more
wiley +1 more source
Acute health risks related to the presence of cyanogenic glycosides in raw apricot kernels and products derived from raw apricot kernels [PDF]
, 2018 Peer reviewedPublisher ...
Alexander, Jan +21 more
core +4 more sources
Biochemical and Genetic Characterization of PspE and GlpE, Two Single-domain Sulfurtransferases of Escherichia coli [PDF]
, 1935 The pspE and glpE genes of Escherichia coli encode periplasmic and cytoplasmic single-domain rhodaneses, respectively, that catalyzes sulfur transfer from thiosulfate to thiophilic acceptors.
Cheng, Hui +4 more
core +2 more sources
Characterization of a sulfurtransferase from Arabidopsis thaliana [PDF]
European Journal of Biochemistry, 2000 A database search for similarities between sequenced parts of the Arabidopsis thaliana genome with known sulfurtransferase sequences from Escherichia coli and mammals was undertaken to obtain information about plant sulfurtransferase‐like proteins. One gene and several homologous EST clones were identified.
J, Papenbrock, A, Schmidt
openaire +2 more sources
Cyanide Beyond Toxicity: A Systematic Review of Its Effects on Vascular Function
Basic &Clinical Pharmacology &Toxicology, Volume 137, Issue 5, November 2025.ABSTRACT Cyanide is widely recognized for its potent toxicity, yet evidence shows that concentrations below 1 μM may enhance cytochrome c oxidase activity and have a regulatory function. Recent findings also demonstrate that mammalian cells, including endothelial cells, produce cyanide endogenously, where it can modulate mitochondrial bioenergetics ...
Elif Alan‐Albayrak, Ulf Simonsen
wiley +1 more source
British Journal of Pharmacology, Volume 182, Issue 22, Page 5453-5468, November 2025.Background and Purpose Hydrogen sulphide (H2S) is synthesised endogenously through cystathionine β‐synthase (CBS), cystathionine γ‐lyase (CSE) and 3‐mercaptopyruvate sulfurtransferase (3‐MST). Although exogenous H2S is known to produce vasodilatation, the vascular effect of H2S produced through 3‐MST is unknown. In this study, we demonstrate the effect
Maha Almaheize +7 more
wiley +1 more source
Microcirculation, Volume 32, Issue 7, October 2025.ABSTRACT Endothelial cells (ECs) express an array of integral membrane proteins, including ion channels and transporters that contribute to blood flow regulation and cell–cell communication. Many of these membrane proteins are regulated by plasma membrane cholesterol content.
Jacob R. Anderson +3 more
wiley +1 more source