Results 61 to 70 of about 12,154 (204)

Patterns of Antibiotic Dispensing Among New Zealand Children: A Linkage Study

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 9, September 2026.
ABSTRACT Background Overuse of antibiotics contributes to antibiotic resistance, and may result in gut microbiome dysbiosis, potentially increasing the risk of chronic childhood conditions. Objectives To examine patterns of antibiotic dispensing in utero and during the first 5 years of life.
Sharan Ram, Marine Corbin, Amanda Kvalsvig, Michael G. Baker, Andrea ‘t Mannetje, Amanda Eng, Jeroen Douwes   +6 more
wiley   +1 more source

Sulphonamides with Diuretic Activity [PDF]

Nature, 1959
RECENTLY we have reported that sulphonamides with a substituted amido-group that is, compounds deprived of any inhibitory action on carbonic anhydrase, may possess a high diuretic activity1. The most active compound of the series is 4-amino-6-chloro-benzene-1,3-disulphonmethylamide (I).
W, LOGEMANN, P N, GIRALDI, M A, PARENTI
openaire   +2 more sources

Synthesis and Antimicrobial Evaluation of Some Pyrazole Derivatives

Molecules, 2012
Reaction of a series of <em>(E)</em>-3-phenyl-4-(<em>p</em>-substituted phenyl)-3-buten-2-ones with <em>p</em>-sulfamylphenyl hydrazine in glacial acetic acid gave the corresponding hydrazones, subsequent treatment of ...
Nagwa Mohamed Mahrous Hamada, Essam Mohamed Sharshira   +1 more
doaj   +1 more source

Survey of Smallholder Dairy Cattle Farming System and Antibiotic Residues in Raw Cow's Milk in Bagamoyo District, Tanzania

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Smallholder dairy farmers in Tanzania face livestock disease challenges that drive imprudent antimicrobial use and fuel antimicrobial resistance (AMR). In Bagamoyo, poor husbandry and limited disease control result in high prevalence of vector‐borne infections, commonly treated with oxytetracycline (OTC).
Ridhiwan I. Ramadhani, Hezron Emmanuel Nonga   +1 more
wiley   +1 more source

Discovery of a novel 4-pyridyl SLC-0111 analog targeting tumor-associated carbonic anhydrase isoform IX through tail-based design approach with potent anticancer activity

Frontiers in Chemistry
Introduction: Carbonic anhydrase IX (CA IX) is a tumor-associated enzyme involved in cancer progression and survival. Targeting CA IX with selective inhibitors like SLC-0111 has shown therapeutic potential.
Hamada Hashem, Shadwa Abdelfattah, Hesham M. Hassan, Ahmed Al-Emam, Mohammed Alqarni, Ghallab Alotaibi, Ibrahim Taha Radwan, Kirandeep Kaur, Devendra Pratap Rao, Stefan Bräse, Abdullah Alkhammash   +10 more
doaj   +1 more source

Prevalence of Mastitis in Cows and Raw Milk Microbial Contamination in Selected Districts, Tanzania

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Cow milk produced in Tanzania suffers from poor quality due to bacterial contamination from mastitis udder predisposed by poor livestock husbandry and milk hygienic practices. The prevalence of mastitis was 75.6%, with a milk bacterial contamination rate of 78% and resistance to multiple antimicrobials. To safeguard the dairy industry and public health,
C. Faustine Ndyamukama, G. Msalya, Hezron Emmanuel Nonga   +2 more
wiley   +1 more source

An in vitro investigation of predisposition to sulphonamide idiosyncratic toxicity in dogs

Sulphonamide idiosyncratic toxicosis has been reported in 28 dogs. Non-septic polyarthritis and fever occurring after 8 to 21 days therapy was the most common manifestation. Of 22 dogs with this syndrome, 7 were Doberman Pinschers.

core   +1 more source

Production of tumour necrosis factor by cells exposed to sulphonamide reactive metabolites

, 1992
Hypersensitivity reactions are the most common adverse events associated with therapy with the sulphonamide antibiotics. These reactions have been shown to occur among individuals with pharmacogenetically determined differences in the capacity of their ...
Ingrid A. Bird, Michael J. Rieder, Monica Mask   +2 more
core   +1 more source

Isolation, Associated Factors and Antimicrobial Susceptibility Patterns of Salmonella spp. in Human Stool, Eggshell Swab and Feces of Egg‐Laying Hens in Mekelle and Southeast Zones of Tigrai, Ethiopia

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Illustration of Possible Salmonella spp. Contamination Pathways among the Animal‐Food‐Human‐Environment Interface at the Poultry Farm Settings. Source: Author's illustration. ABSTRACT Background Salmonellosis is an important foodborne and zoonotic disease commonly related to the ingestion of poultry products contaminated with Salmonella spp. Although a
Atsebaha Gebrekidan Kahsay, Tsehaye Asmelash, Enquebaher Kassaye   +2 more
wiley   +1 more source

O95 - Optimising trimethoprim–sulphonamide synergy against Actonibacillus pleuropneumoniae

International audienceBackground: Trimethoprim (TMP) and sulphonamides are widely used in combination to treat porcine respiratory infections caused by Actinobacillus pleuropneumoniae (APP).
Toutain, Pierre-Louis, Mead, Andrew, Ferran, Aude, Boulanger, Marine, Overesch, Gudrun, Pelligand, Ludovic, Viel, Alexis   +6 more
core   +1 more source