Results 111 to 120 of about 168,667 (308)
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Random graph models for wireless communication networks
, 2010 PhDThis thesis concerns mathematical models of wireless communication networks, in particular ad-hoc networks and 802:11 WLANs. In ad-hoc mode each of these devices may function as a sender, a relay or a receiver.
Song, Linlin
core
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
Uniform distribution and sum modulo m of independent random variables
If one of two independent random variables (possibly both) is uniformly distributed, then so is their sum modulo m; we show that the converse is true if m is a prime number and the relevant probabilities are rational numbers.Modulo m sum modulo m sum ...
Scozzafava, Paola
core
, 2013 : Let X and Y be independent random variables, X having a gamma distribution with shape parameter a and Y having a non-central gamma distribution with shape and non-centrality parameters b and δ, respectively. Define Z = X/(X + 2Y ).
Nagar, Daya Krishna +1 more
core +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Moments tensors, Hilbert's identity, and k-wise uncorrelated random variables [PDF]
, 2014 Li, Zhening +3 more
core +1 more source
Cumulants of the nonlinear combination of independent random variables
, 1991 A random variable of interest is often the sum of linear or nonlinear combinations of many independent random variables. In calculating the statistics of this random sum, advantages of simplicity and computational efficiency can be obtained by operating ...
Hu, Sau-Lon James
core
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source