Results 171 to 180 of about 175,802,720 (255)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Evidence Summary of Early Enteral Nutrition Support for Adult Patients with Extracorporeal Membrane Oxygenation (ECMO)

Journal of Multidisciplinary Healthcare
Jixiang Guo,1,2 Zhiyi Wang,2 Aiqun Liang,1 Zhi Qu,2 Hanru Bao,1,2 Kexi Pei,3 Xiaoping Luo1 1Surgery and Anesthesiology Department 1, Zhongshan People’s Hospital, Zhongshan, Guangdong, 528403, People’s Republic of China; 2School of Nursing and Health ...
Guo J, Wang Z, Liang A, Qu Z, Bao H, Pei K, Luo X   +6 more
doaj  

Bone health management in endocrine-treated patients with prostate cancer: a summary of evidence. [PDF]

BMC Urol
Chen L, Shuang H, Qingjian W, Jingzhen Z, Ji Z, Yu C.   +5 more
europepmc   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Summary of Best Evidence for the Management and Recurrence Prevention of Febrile Seizures in Children

Journal of Multidisciplinary Healthcare
Rongzhu Tang,1 Min Wang,2 Xue He,1 Qi He,1 Lan Chen,1 Dingxiang Liu1 1Department of Pediatrics, Suining Central Hospital, Suining, Sichuan, People’s Republic of China; 2Department of Respiratory and Critical Care Medicine, Suining Central Hospital ...
Tang R, Wang M, He X, He Q, Chen L, Liu D   +5 more
doaj  

Pediatric wrist fractures: variations in management across countries. An evidence-based summary of evidence. [PDF]

Br Med Bull
Labianca L, Calderaro C, Maffulli N.
europepmc   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Evidence Summary of Early Enteral Nutrition Support for Adult Patients with Extracorporeal Membrane Oxygenation (ECMO) [Corrigendum]

Journal of Multidisciplinary Healthcare
Guo J, Wang Z, Liang A, et al. J Multidiscip Healthc. 2025;18:1557–1569. https://doi.org/10.2147/JMDH.S513246 After publication, concerns have been raised by a third party regarding missing steps in Figure 1 on page 1560 of the published ...
Guo J, Wang Z, Liang A, Qu Z, Bao H, Pei K, Luo X   +6 more
doaj  

Summary of evidence on prevention and management of bladder dysfunction in patients after radical hysterectomy. [PDF]

Nurs Open
Zeng C, Mi Y, Wang F, Zhao Q, Xiao M, Xiao F, Hu Y, Wang L, He F.   +8 more
europepmc   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source