Results 161 to 170 of about 175,802,720 (255)

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Summary of evidence on nutritional adherence in cardiac rehabilitation among patients with coronary heart disease after PCI based on mobile healthcare systems. [PDF]

Digit Health
Hu Y, Lu D, Yi J, Wang M, Liang J, Li J.
europepmc   +1 more source

An umbrella review comparing computer-assisted and conventional total joint arthroplasty: quality assessment and summary of evidence. [PDF]

BMJ Surg Interv Health Technol, 2020
Hasan MM, Zhang M, Beal M, Ghomrawi HMK.
europepmc   +1 more source

An Evidence Summary of Health Education in Chronic Obstructive Pulmonary Disease: A Practice-Oriented Assessment with Inter-Rater Reliability

International Journal of COPD
Miao Zhan,1,2 Jing Chen,2,3 Changfu Chen,2 Jiali Zhou,2 Hongying Zhang1,21Department of Science and Education, The Affiliated Rehabilitation Hospital of Chongqing Medical University, Chongqing, 400084, People’s Republic of China; 2School of Nursing ...
Zhan M, Chen J, Chen C, Zhou J, Zhang H
doaj  

An umbrella review for preoperative rehabilitation in primary total knee arthroplasty: quality assessment and summary of evidence. [PDF]

BMC Musculoskelet Disord
Zhao Y, Tian C, Tian S, Han W, Shi H, Cao M, Liu J.   +6 more
europepmc   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Summary of Evidence on Nutritional Management for Patients Undergoing Chemotherapy. [PDF]

Cancer Med
Dan X, He YL, Tian YL, Chen TL, Yu JY.
europepmc   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Development of a Stepped-Care Pathway for Managing Willis-Ekbom Disease/Restless Legs Syndrome During Pregnancy: A Best Evidence Synthesis

Nature and Science of Sleep
Fei-Yi Zhao,1– 4,* Li-Ping Yue,1,* Russell Conduit,2 Yan-Mei Wang,4 Wen-Jing Zhang,4 Peijie Xu,5 Yuen-Shan Ho,6 Qiang-Qiang Fu,7 Chin Moi Chow3,8 1Department of Nursing, School of International Medical Technology, Shanghai Sanda ...
Zhao FY, Yue LP, Conduit R, Wang YM, Zhang WJ, Xu P, Ho YS, Fu QQ, Chow CM   +8 more
doaj  

The impact of non-invasive brain-computer interface technology on the therapeutic effect of patients with spinal cord injury: a summary of evidence based on meta-analysis. [PDF]

J Neuroeng Rehabil
Sun Z, Hu S, Zhu J, Ye Z, Ma M, Ma G.
europepmc   +1 more source