Results 141 to 150 of about 175,802,720 (255)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

COVID-19 Health Evidence Summary No.25

open access: yes, 2020
This daily COVID-19 Health Evidence Summary is to signpost DFID and other UK government departments to the latest relevant evidence and discourse on COVID-19 to inform and support their response.
Kerry Millington (210010)
core  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Summary of the Best Evidence for the Prevention and Management of Medical Adhesive-Related Skin Injuries in Patients with Tracheal Intubation

open access: yesJournal of Multidisciplinary Healthcare
Minhua Hu, Jiajia Hu, Peng Sun, Hongyan Zheng, Mingyang Zhang The First Department of Surgical Anesthesiology, Zhongshan People’s Hospital, Zhongshan, Guangdong, 528403, People’s Republic of ChinaCorrespondence: Minhua Hu, The First Department of ...
Hu M, Hu J, Sun P, Zheng H, Zhang M
doaj  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

COVID-19 Health Evidence Summary No.24

open access: yes, 2020
This daily COVID-19 Health Evidence Summary is to signpost DFID and other UK government departments to the latest relevant evidence and discourse on COVID-19 to inform and support their response.
Kerry Millington (210010)
core  

Evidence summary for perioperative access site management in distal transradial coronary intervention

open access: yesHuli yanjiu, 2023
SHI Xiushan   +5 more
doaj  

Evidence Summary of Management Strategies for Cognitive Impairment in Patients with Heart Failure

open access: yesJournal of Multidisciplinary Healthcare
Fu Ni,1– 3,* Wentao Mi,1,2,* Yongting Wei,1,2 Zifeng Li,1,2 Yuqing Fan,1– 3 Zuyang Xi1,2 1The First College of Clinical Medical Science, China Three Gorges University, Yichang, Hubei, 443000, People’s Republic of China; 2Department of ...
Ni F, Mi W, Wei Y, Li Z, Fan Y, Xi Z
doaj  

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy