Results 91 to 100 of about 291,935 (374)
Time-domain parametric sensitivity analysis of multiconductor transmission lines [PDF]
, 2011 We present a new parametric macromodeling technique for lossy and dispersive multiconductor transmission lines (MTLs). This technique can handle design parameters, such as substrate or geometrical layout features, and provide time-domain sensitivity ...
Antonini, G +4 more
core +2 more sources
Advanced Science, EarlyView.A simplified chemoenzymatic platform is designed to integrate an enzyme cascade with subsequent chemical steps, enabling the divergent production of diverse benzylisoquinoline alkaloids (BIAs). Demonstrating remarkable versatility and enantioselectivity, four distinct classes of BIAs are efficiently generated, in which the natural medicine papaverine ...
Huiling Liu +8 more
wiley +1 more source
Annals of Neurology, EarlyView.Objectives Multiple sclerosis (MS) onset risk factors include Epstein–Barr virus (EBV) indices (including host response), lower serum 25‐vitamin D (25(OH)D) levels, low sun exposure, and HLA‐DRB1*1501. The underlying molecular mechanisms are unclear. Here, we examined mediation through differential DNA methylation (DNAm) to better understand possible ...
Steve Simpson‐Yap +37 more
wiley +1 more source
A Method for SUMO Modification of Proteins in vitro
Bio-Protocol, 2018 The Small Ubiquitin-related Modifier (SUMO) is a protein that is post-translationally added to and reversibly removed from other proteins in eukaryotic cells.
Christine Lee +3 more
doaj +1 more source
SUMO and KSHV Replication [PDF]
Cancers, 2014 Small Ubiquitin-related MOdifier (SUMO) modification was initially identified as a reversible post-translational modification that affects the regulation of diverse cellular processes, including signal transduction, protein trafficking, chromosome segregation, and DNA repair.
Pei Ching Chang, Hsing Jien Kung
openaire +3 more sources
SUMOylation in Trypanosoma brucei [PDF]
PeerJ, 2013 Small ubiquitin like modifier (SUMO) proteins are involved in many processes in eukaryotes. We here show that Trypanosoma brucei SUMO (Tb927.5.3210) modifies many proteins.
Cornelia Andrea Klein +2 more
doaj +2 more sources
Nature Communications, 2019 Modification with SUMO regulates many eukaryotic proteins. Down-regulation of sumoylated forms of proteins involves either their desumoylation, and hence recycling of the unmodified form, or their proteolytic targeting by ubiquitin ligases that recognize
A. M. Sriramachandran +8 more
semanticscholar +1 more source
Journal of the Association for Information Science and Technology, EarlyView.Abstract The term semantic primitives refers to a set of basic, atomic concepts from which all other (compound) concepts are constructed. It presupposes the principle of compositionality—the idea that complex items or expressions can be formed by combining simpler constituents.
Birger Hjørland
wiley +1 more source
Global SUMO proteome responses guide gene regulation, mRNA biogenesis, and plant stress responses
Frontiers in Plant Science, 2012 Small-ubiquitin-like MOdifier (SUMO) is a key regulator of abiotic stress, disease resistance and development in plants. The identification of >350 plant SUMO targets has revealed many processes modulated by SUMO and potential consequences of SUMO on ...
Magdalena eMazur +1 more
doaj +1 more source