Results 121 to 130 of about 300,823 (367)

The SUMO E3 Ligase MdSIZ1 Targets MdbHLH104 to Regulate Plasma Membrane H+-ATPase Activity and Iron Homeostasis1[OPEN]

open access: yesPlant Physiology, 2018
The SUMO E3 ligase MdSIZ1 sumoylates and stabilizes MdbHLH104 to increase PM H+-ATPase mediated rhizosphere acidification and Fe acquisition under conditions of Fe deficiency in apple.
Li-Jie Zhou   +5 more
semanticscholar   +1 more source

SUMOylation of NaV1.2 channels mediates the early response to acute hypoxia in central neurons. [PDF]

open access: yes, 2016
The mechanism for the earliest response of central neurons to hypoxia-an increase in voltage-gated sodium current (INa)-has been unknown. Here, we show that hypoxia activates the Small Ubiquitin-like Modifier (SUMO) pathway in rat cerebellar granule ...
Goldstein, Steve An   +2 more
core   +2 more sources

Chemical Methods for Peptide and Protein Backbone Cleavage

open access: yesChemistryEurope, EarlyView.
Protein cleavage plays essential roles in biology and is powerful for protein manipulation and functionalization as well as in recombinant expression and purification. Here, the historical background and most recent examples of chemical methods for protein and peptide backbone cleavage are discussed (part of the figure was generated in BioRender).
Miguel Angel Alena‐Rodriguez   +1 more
wiley   +1 more source

The potential role of As-sumo-1 in the embryonic diapause process and early embryo development of Artemia sinica.

open access: yesPLoS ONE, 2014
During embryonic development of Artemia sinica, environmental stresses induce the embryo diapause phenomenon, required to resist apoptosis and regulate cell cycle activity.
Bing Chu   +9 more
doaj   +1 more source

A role for SUMO modification in transcriptional repression and activation [PDF]

open access: yes, 2007
Since the discovery of the SUMO (small ubiquitin-like modifier) family of proteins just over a decade ago, a plethora of substrates have been uncovered including many regulators of transcription.
David   +26 more
core   +1 more source

Strong Nonradiative Recombination Induced by Pronounced Lone‐Pair Electron Expression Following Deprotonation in Aziridinium Lead Iodide Perovskites

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
The transition from linear to cyclic organic cations promotes deprotonation and activates VH(N) defects with pronounced lone‐pair electron activity, thereby inducing severe local distortions and highly efficient nonradiative recombination centers. This work unveils a direct structure–defect–performance correlation and proposes design strategies for the
Qingshan Bao   +5 more
wiley   +1 more source

Deep Reinforcement Learning Approach for Traffic Light Control and Transit Priority

open access: yesFuture Transportation
This study investigates the use of deep reinforcement learning techniques to improve traffic signal control systems through the integration of deep learning and reinforcement learning approaches.
Saeed Mansouryar   +3 more
doaj   +1 more source

SENP7 Potentiates cGAS Activation by Relieving SUMO-Mediated Inhibition of Cytosolic DNA Sensing

open access: yesPLoS Pathogens, 2017
Cyclic GMP-AMP (cGAMP) synthase (cGAS, a.k.a. MB21D1), a cytosolic DNA sensor, catalyzes formation of the second messenger 2’3’-cGAMP that activates the stimulator of interferon genes (STING) signaling.
Ye Cui   +12 more
semanticscholar   +1 more source

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