Results 251 to 260 of about 291,935 (374)

The activity of the EMT suppressor GRHL2 is regulated by SUMOylation. [PDF]

J Biol Chem
Santjer S, Xu Y, Riethdorf S, Schön G, Neu J, Pantel K, Assmann V.   +6 more
europepmc   +1 more source

Guanine Nucleotide Exchange Factors and Small GTPases: Their Regulation and Functions, Diseases, and Therapeutic Targets

MedComm, Volume 6, Issue 10, October 2025.
This review comprehensively examines the regulatory mechanisms and physiological roles of guanine nucleotide exchange factors (GEFs) and their small GTPase substrates, highlighting their significance in cellular processes and disease pathogenesis.
Zexing Lin, Chujun Ni, Haiyang Jiang, Huan Yang, Liting Deng, Peizhao Liu, Xuanheng Li, Yilong Yu, Weijie Li, Runnan Wang, Bo Liao, Jiaqi Kang, Juanhan Liu, Xiuwen Wu, Jianan Ren, Yun Zhao   +15 more
wiley   +1 more source

Waking Up to HIV/AIDS in War Ravaged Liberia, The Difficulties in Instituting HIV/AIDS Awareness Programs

Retrovirology, 2005
Sumo Johnson
doaj   +1 more source

Development of a Method for Producing Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor Using Fusion Protein Technology. [PDF]

Curr Issues Mol Biol
Volosnikova EA, Esina TI, Volkova NV, Belenkaya SV, Gogina YS, Shimina GG, Vyazovaya EA, Gamaley SG, Danilenko ED, Shcherbakov DN.   +9 more
europepmc   +1 more source

Mitochondria‐Associated Endoplasmic Reticulum Membranes in Health and Diseases

MedComm, Volume 6, Issue 10, October 2025.
As pivotal regulators in diverse physiological and pathological processes, mitochondria‐associated endoplasmic reticulum membranes (MAMs) are critically involved in both health and diseases, including cancers, neurodegenerative disorders, metabolic diseases, cardiovascular diseases.
Hangnan Hong, Zhenyang Guo, Junbo Ge, Hua Li   +3 more
wiley   +1 more source

The fission yeast SUMO-targeted ubiquitin ligase Slx8 functionally associates with clustered centromeres and the silent mating-type region at the nuclear periphery

Biology Open
Shrena Chakraborty, Joanna Strachan, Kamila Schirmeisen, Laetitia Besse, Eve Mercier, Karine Fréon, Haidao Zhang, Ning Zhao, Elizabeth H. Bayne, Sarah A. E. Lambert   +9 more
doaj   +1 more source

Transcription factor Sp3 is silenced through SUMO modification by PIAS1 [PDF]

, 2002
Alexandra Sapetschnig, Grigore Rischitor, Harald Braun, Andreas Doll, Marion Schergaut, Frauke Melchior, Guntram Suske   +6 more
openalex   +1 more source

SUMOylome Profiling Reveals a Diverse Array of Nuclear Targets Modified by the SUMO Ligase SIZ1 during Heat Stress

The Plant Cell, 2018
Thérèse C. Rytz, Marcus J. Miller, Fionn McLoughlin, Robert C. Augustine, R. S. Marshall, Yu-ting Juan, Y. Charng, M. Scalf, Lloyd M. Smith, R. Vierstra   +9 more
semanticscholar   +1 more source

Free Radicals in Health and Disease

MedComm, Volume 6, Issue 10, October 2025.
Free radicals have dual roles that can either selectively create oxidative damages to transformed cells in treating proliferative diseases such as cancers and some dermatological disorders or boost the antioxidant system in treating degenerative diseases such as neurodegenerative disorder, joint degeneration, and metabolic conditions.
Xiaofeng Dai, Zizheng Huang, Ruohan Lyu
wiley   +1 more source

HDAC6-dependent deacetylation of SAE2 enhances SUMO1 conjugation for mitotic integrity. [PDF]

EMBO J
Lanz AJ, Walker AK, Jamshad M, Garvin AJ, Stewart M, Wotherspoon P, Cooper BF, Mackintosh M, Crutchley O, Knowles TJ, Morris JR.   +10 more
europepmc   +1 more source