Results 111 to 120 of about 13,776 (215)
Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction
PROTEOMICS, EarlyView.ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella +6 more
wiley +1 more source
Biomimetic Robotics and Intelligence: A Survey
SmartBot, EarlyView.Biomimetic robotics and intelligence, inspired by biological systems, integrate biology, engineering, and AI, develops robots capable of adapting to complex environments. By mimicking natural structures and cognitive processes, and employing algorithms like neural networks and genetic algorithms, these systems enhance autonomy and problem‐solving. This
Yixuan Sheng +6 more
wiley +1 more source
Epstein-Barr Virus Immediate-Early Protein BZLF1 Is SUMO-1 Modified and Disrupts Promyelocytic Leukemia Bodies [PDF]
, 2001 A. L. Adamson, S. Kenney
openalex +3 more sources
Black-box Testing of First-Order Logic Ontologies Using WordNet [PDF]
arXiv, 2017 Artificial Intelligence aims to provide computer programs with commonsense knowledge to reason about our world. This paper offers a new practical approach towards automated commonsense reasoning with first-order logic (FOL) ontologies. We propose a new black-box testing methodology of FOL SUMO-based ontologies by exploiting WordNet and its mapping into
arxiv
British Journal of Pharmacology, EarlyView.▪ Background and Purpose NLRP3 is up‐regulated in inflammatory and autoimmune diseases. The development of NLRP3 inhibitors is challenged by the identification of compounds with distinct mechanisms of action avoiding side effects and toxicity. Triptolide is a natural product with multiple anti‐inflammatory activities, but a narrow therapeutic window ...
Mo‐Yu Ding +5 more
wiley +1 more source
Multifaceted roles of SUMO in DNA metabolism
NucleusSumoylation, a process in which SUMO (small ubiquitin like modifier) is conjugated to target proteins, emerges as a post-translational modification that mediates protein−protein interactions, protein complex assembly, and localization of target proteins.
Yee Mon Thu
doaj +1 more source
Cell Proliferation, EarlyView.PDHA2, a testis‐specific subunit of pyruvate dehydrogenase, is required for the conversion of pyruvate to acetyl‐CoA. Its absence results in decreased acetyl‐CoA and precursors for metabolites and energy during spermatogenesis. This results in decreased histone acetylation, defective chromosome structure and moderately reduced crossovers, ultimately ...
Guoqiang Wang +9 more
wiley +1 more source
Viral Immediate-Early Proteins Abrogate the Modification by SUMO-1 of PML and Sp100 Proteins, Correlating with Nuclear Body Disruption [PDF]
, 1999 Stefan Müller, Anne Dejean
openalex +1 more source
Membraneless Organelles and Phase Separation in Tumours: Mechanisms and Prospects
Cell Proliferation, EarlyView.The Salient and Novel Findings: This article summarises the latest research advancements in phase separation within tumours, with a particular focus on the role and molecular mechanisms of liquid–liquid phase separation (LLPS) in tumour progression.
Hao Yang +3 more
wiley +1 more source
High‐Fidelity In Vitro Packaging of Diverse Synthetic Cargo into Encapsulin Protein Cages
Angewandte Chemie, Volume 137, Issue 23, June 2, 2025.Pack n’ Play. A novel in vitro assembly system for encapsulin protein cages has been developed. Using a bulky fusion partner to prevent shell assembly in cellulo, high‐fidelity assembly is triggered in vitro by proteolytic cleavage yielding robust particles with superior thermostability.
Taylor N. Szyszka +8 more
wiley +2 more sources