Results 11 to 20 of about 13,776 (215)
Identification of a SUMO-binding motif that recognizes SUMO-modified proteins [PDF]
Proceedings of the National Academy of Sciences, 2004 Posttranslational modification by the ubiquitin homologue, small ubiquitin-like modifier 1 (SUMO-1), has been established as an important regulatory mechanism. However, in most cases it is not clear how sumoylation regulates various cellular functions.
Theodore G. Krontiris +4 more
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Genetic and proteomic evidence for roles of Drosophila SUMO in cell cycle control, Ras signaling, and early pattern formation. [PDF]
PLoS ONE, 2009 SUMO is a protein modifier that is vital for multicellular development. Here we present the first system-wide analysis, combining multiple approaches, to correlate the sumoylated proteome (SUMO-ome) in a multicellular organism with the developmental ...
Minghua Nie +3 more
doaj +1 more source
A Realistic Cyclist Model for SUMO Based on the SimRa Dataset [PDF]
20th IEEE Mediterranean Communication and Computer Networking
Conference (MedComNet 2022), Paphos, Cyprus, June 2022, pp. 166-173, 2022 Increasing the modal share of bicycle traffic to reduce carbon emissions, reduce urban car traffic, and to improve the health of citizens, requires a shift away from car-centric city planning. For this, traffic planners often rely on simulation tools such as SUMO which allow them to study the effects of construction changes before implementing them ...
arxiv +1 more source
Enhanced in vitro refolding of fibroblast growth factor 15 with the assistance of SUMO fusion partner. [PDF]
PLoS ONE, 2011 Fibroblast growth factor 15 (Fgf15) is the mouse orthologue of human FGF19. Fgf15 is highly expressed in the ileum and functions as an endocrine signal to regulate liver function, including bile acid synthesis, hepatocyte proliferation and insulin ...
Bo Kong, Grace L Guo
doaj +1 more source
The Polycomb Protein Pc2 Is a SUMO E3 [PDF]
Cell, 2003 Polycomb group (PcG) proteins form large multimeric complexes (PcG bodies) which are involved in the stable repression of gene expression. The human PcG protein, Pc2, has been shown to recruit the transcriptional corepressor, CtBP, to PcG bodies. We show that CtBP is sumoylated at a single lysine.
Michael H. Kagey +2 more
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Forkhead box protein A2 (FOXA2) protein stability and activity are regulated by sumoylation. [PDF]
PLoS ONE, 2012 The forkhead box protein A2 (FOXA2) is an important regulator of glucose and lipid metabolism and organismal energy balance. Little is known about how FOXA2 protein expression and activity are regulated by post-translational modifications.
Narasimhaswamy S Belaguli +3 more
doaj +1 more source
SUMO-2 promotes mRNA translation by enhancing interaction between eIF4E and eIF4G. [PDF]
PLoS ONE, 2014 Small ubiquitin-like modifier (SUMO) proteins regulate many important eukaryotic cellular processes through reversible covalent conjugation to target proteins.
Li-zhao Chen +12 more
doaj +1 more source
SUMO: of branched proteins and nuclear bodies [PDF]
Oncogene, 2001 SUMO belongs to a growing number of ubiquitin-like proteins that covalently modify their target proteins. Although some evidence supports a role of SUMO modification in regulating protein stability, most studied examples support a model by which SUMO alters the interaction properties of its targets, often affecting their subcellular localization ...
Seeler, Jacob-Sebastian, Dejean, Anne
openaire +3 more sources
PLoS ONE, 2014 During embryonic development of Artemia sinica, environmental stresses induce the embryo diapause phenomenon, required to resist apoptosis and regulate cell cycle activity.
Bing Chu +9 more
doaj +1 more source
Regulation of the Expression of DAPK1 by SUMO Pathway
Biomolecules, 2019 Death Associated Protein Kinase 1 (DAPK1) is an important signaling kinase mediating the biological effect of multiple natural biomolecules such as IFN-γ, TNF-α, curcumin, etc.
Qingshui Wang +13 more
doaj +1 more source