Results 31 to 40 of about 13,776 (215)
How Does SUMO Participate in Spindle Organization?
Cells, 2019 The ubiquitin-like protein SUMO is a regulator involved in most cellular mechanisms. Recent studies have discovered new modes of function for this protein.
Ariane Abrieu, Dimitris Liakopoulos
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Simplifying recombinant protein production: Combining Golden Gate cloning with a standardized protein purification scheme [PDF]
arXiv, 2023 Recombinant protein production is pivotal in molecular biology, enabling profound insights into cellular processes through biophysical, biochemical, and structural analyses of the purified samples. The demand for substantial biomolecule quantities often presents challenges, particularly for eukaryotic proteins.
arxiv
Super Resolution Microscopy of SUMO Proteins in Neurons [PDF]
Frontiers in Cellular Neuroscience, 2019 The ubiquitously expressed SUMO proteins regulate a plethora of cellular pathways and processes. While they have a predominantly nuclear localization, extranuclear roles of SUMO isoforms at the synapse have also been described, making SUMOylation one of the major post-translational regulators of nerve functions.
Colnaghi L +7 more
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Functional reconstitution of a tunable E3-dependent sumoylation pathway in Escherichia coli. [PDF]
PLoS ONE, 2012 SUMO (small ubiquitin-related modifier) is a reversible post-translational protein modifier that alters the localization, activity, or stability of proteins to which it is attached.
Sean P O'Brien, Matthew P DeLisa
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Microbiology Spectrum, 2023 Persistence of hepatitis B virus (HBV) infection is due to a nuclear covalently closed circular DNA (cccDNA), generated from the virion-borne relaxed circular DNA (rcDNA) genome in a process likely involving numerous cell factors from the host DNA damage
Samuel Hofmann +14 more
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Bad Weather, Social Network, and Internal Migration; Case of Japanese Sumo Wrestlers 1946-1985 [PDF]
arXiv, 2022 Post-World War II , there was massive internal migration from rural to urban areas in Japan. The location of Sumo stables was concentrated in Tokyo. Hence, supply of Sumo wrestlers from rural areas to Tokyo was considered as migration. Using a panel dataset covering forty years, specifically 1946-1985, this study investigates how weather conditions and
arxiv
SUMO Modification: Wrestling with Protein Conformation [PDF]
Current Biology, 2005 SUMO modification of human thymine-DNA glycosylase facilitates the processing of base excision repair substrates by an unusual mechanism: while leaving the catalytic center unaffected, it induces product release by eliciting a conformational change in the enzyme.
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A Chain of Events: Regulating Target Proteins by SUMO Polymers [PDF]
Trends in Biochemical Sciences, 2021 Small ubiquitin-like modifiers (SUMOs) regulate virtually all nuclear processes. The fate of the target protein is determined by the architecture of the attached SUMO protein, which can be of polymeric nature. Here, we highlight the multifunctional aspects of dynamic signal transduction by SUMO polymers.
Jansen, N.S., Vertegaal, A.C.O.
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USE OF SUMO-EXPRESSION SYSTEM AND SUMO-PROTEASE FOR PRODUCTION OF ACTIVE INTERFERON α-2b [PDF]
Biotechnologia ActaRecombinant proteins production in prokaryotic expression systems is often complicated by need of native, N-terminal formylmethionine free molecule extraction, refolding, and processing.
I-M.M. KLYMKOVYCH, M.M. SKRYNNYK
doaj +1 more source
Tomosyn interacts with the SUMO E3 ligase PIASγ. [PDF]
PLoS ONE, 2014 Protein modification by Small Ubiquitin-like MOdifier (SUMO) entities is involved in a number of neuronal functions, including synaptogenesis and synaptic plasticity. Tomosyn-1 (syntaxin-binding protein 5; STXPB5) binds to t-SNARE (Soluble NSF Attachment
Cornelia J Geerts +4 more
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