Results 171 to 180 of about 31,613 (261)

TRIM28 drives immune evasion via PARP1 SUMOylation and NAD<sup>+</sup> depletion in clear cell renal cell carcinoma. [PDF]

open access: yesJ Immunother Cancer
Zhan X   +10 more
europepmc   +1 more source

Guanine Nucleotide Exchange Factors and Small GTPases: Their Regulation and Functions, Diseases, and Therapeutic Targets

open access: yesMedComm, Volume 6, Issue 10, October 2025.
This review comprehensively examines the regulatory mechanisms and physiological roles of guanine nucleotide exchange factors (GEFs) and their small GTPase substrates, highlighting their significance in cellular processes and disease pathogenesis.
Zexing Lin   +15 more
wiley   +1 more source

Transforming Growth Factor-β-independent Regulation of Myogenesis by SnoN Sumoylation [PDF]

open access: hybrid, 2007
Katharine H. Wrighton   +6 more
openalex   +1 more source

Mitochondria‐Associated Endoplasmic Reticulum Membranes in Health and Diseases

open access: yesMedComm, Volume 6, Issue 10, October 2025.
As pivotal regulators in diverse physiological and pathological processes, mitochondria‐associated endoplasmic reticulum membranes (MAMs) are critically involved in both health and diseases, including cancers, neurodegenerative disorders, metabolic diseases, cardiovascular diseases.
Hangnan Hong   +3 more
wiley   +1 more source

UFMylation System: Biological Functions, Molecular Mechanisms, Diseases, and Drug Discovery

open access: yesMedComm, Volume 6, Issue 10, October 2025.
UFMylation, a novel ubiquitin‐like modification, plays an essential role in various cellular processes, such as the immune response, DNA damage repair, unfolded protein response (UPR), autophagy, endoplasmic reticulum (ER)‐phagy, stem cell self‐renewal, apoptosis, and metastasis.
Huiyan Li   +5 more
wiley   +1 more source

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