Results 51 to 60 of about 492,788 (354)

Strategies to reduce the cancer burden and improve access to effective and affordable cancer interventions in Europe

open access: yesMolecular Oncology, EarlyView.
Comprehensive cancer centre (CCCs) and CCCs of Excellence (CCCoE) integration in healthcare. Through outreach to surrounding community hospitals, CCCs enable wider access to top‐clinical cancer treatments and care, thereby facilitating the swift enrolment of patients into data‐rich clinical trials (PI‐initiated trials testing new concepts, drug ...
Anton Berns   +4 more
wiley   +1 more source

Fabrication of a Novel CNT-COO/Ag3PO4@AgIO4Composite with Enhanced Photocatalytic Activity under Natural Sunlight

open access: yesMolecules, 2023
In this study, a carboxylated carbon nanotube-grafted Ag3PO4@AgIO4 (CNT-COO−/Ag3PO4@AgIO4) composite was synthesized through an in situ electrostatic deposition method.
Abdalla A. Elbashir   +5 more
doaj   +1 more source

Xeroderma Pigmentosum [PDF]

open access: yes, 2011
Xeroderma pigmentosum (XP) is defined by extreme sensitivity to sunlight, resulting in sunburn, pigment changes in the skin and a greatly elevated incidence of skin cancers.
Lehmann, Alan R   +2 more
core   +3 more sources

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

open access: yesFEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui   +15 more
wiley   +1 more source

Boundaries of photosynthesis: adaptations of carbon fixation in extreme environments

open access: yesFEBS Open Bio, EarlyView.
Photosynthesis faces challenges from environmental extremes of temperature, pH, and salinity, limiting gas diffusion, modifying membrane fluidity, and destabilizing photochemical and biochemical reactions. Photosynthetic organisms have evolved unique adaptations overcoming these stresses and maintaining their photosynthetic activity.
Pere Aguiló‐Nicolau   +3 more
wiley   +1 more source

Xeroderma pigmentosum: when the sun burns the eyes

open access: yesPAMJ Clinical Medicine, 2020
We report the case of a two-month-old male infant from a consanguine marriage. He had pigmented lesions on the skin of the eyelids, the face, and the neck, alternating with areas of depigmentation.
Aymane Ridallah, Lalla Ouafaa Cherkaoui
doaj   +1 more source

Protective telescoping shield for solar concentrator [PDF]

open access: yes, 1986
An apparatus is described for use with a solar concentrator such as a parabolic dish which concentrates sunlight onto a small opening of a solar receiver, for protecting the receiver in the event of a system failure that could cause concentrated sunlight
Argoud, M. J.   +2 more
core   +1 more source

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

open access: yesAging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal   +8 more
wiley   +1 more source

Sunlight Intensity Based Global Positioning System for Near-Surface Underwater Sensors

open access: yesSensors, 2012
Water monitoring is important in domains including documenting climate change, weather prediction and fishing. This paper presents a simple and energy efficient localization strategy for near surface buoy based sensors. Sensors can be dropped randomly in
Borja Fernández   +2 more
doaj   +1 more source

How Do Seasonal Temperature Patterns Vary Among Different Regions of the World? [PDF]

open access: yes, 2003
The purpose of this resource is to have students use GLOBE visualizations to display student data on maps and to learn about seasonal changes in regional and global temperature patterns.
The GLOBE Program, University Corporation for Atmospheric Research (UCAR)
core  

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