Results 121 to 130 of about 9,553 (254)

Renal‐vascular axis: unmasking its role in vascular endothelial growth factor‐inhibitor vascular toxicity in cancer patients

British Journal of Pharmacology, EarlyView.
Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley   +1 more source

Decline of Visual Function and Risk of Legal Blindness With Age in RPGR‐Associated Retinal Degeneration: A Multicenter Study

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background This retrospective multicenter longitudinal analysis analysed the loss trajectory of best recorded visual acuity (BRVA) and Goldmann visual field (GVF) in RPGR‐associated retinal degeneration (RPGR‐RD). Methods Patients with genetically confirmed RPGR‐RD were classified into rod‐cone (RC), cone/cone‐rod (CR) and female‐carrier ...
Bela J. Parekh, Joshua D. Stein, Rebhi Abuzaitoun, Chris A. Andrews, Kari Branham, Dejan Milentijevic, Divya Narayanan, Naheed W. Khan, Suzann Pershing, Sophia Y. Wang, Baseer U. Ahmad, Thomas B. Connor, Jennifer L. Patnaik, Marc Mathias, Monique Leys, Brian McMillan, Nnana Amakiri, Taylor J. Johnson, Catherine Q. Sun, Jacque L. Duncan, K. Thiran Jayasundera, on behalf of the SOURCE consortium, Sejal Amin, Paul A. Edwards, Divya Srikumaran, Fasika Woreta, Jeffrey S. Schultz, Anurag Shrivastava, Baseer Ahmad, Louis R. Pasquale, Paul J. Bryar, Dustin D. French, Michelle Hribar, Merina Thomas, Brian L. Vanderbeek, Suzann Pershing, Sophia Y. Wang, Michael Deiner, Catherine Sun, Jennifer Patnaik, Prem Subramanian, Saleha Munir, Wuqaas Munir, Joshua Stein, Lindsey De Lott, Rajeev Ramachandran, Robert Feldman, Brian C. Stagg, Barbara Wirostko, Brian McMillian, Arsham Sheybani, Soshian Sarrapour, Kristen Harris‐Nwanyanwu   +52 more
wiley   +1 more source

Incidence, Progression and Determinants of Diabetic Retinopathy in Type 2 Diabetes in Australasia: A Systematic Review and Meta‐Analysis

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background Current evidence on incidence and progression rate of diabetic retinopathy reveals disparities across Australasia, and no pooled estimates are available to guide region‐wide planning. This review and meta‐analysis assesses the overall incidence, determinants and progression of diabetic retinopathy in Australasia.
Getasew Alemu Mersha, Mesert Derbew Molla, Ranjay Chakraborty, Georgia Kaidonis, Stewart Lake, Jamie Craig, José Estevez   +6 more
wiley   +1 more source

Measurements of Sunspot Group Tilt Angles Based on SOHO/MDI and SDO/HMI Magnetograms

The Astrophysical Journal
The tilt angle of sunspot groups plays a crucial role in solar dynamo models for the generation of the poloidal field, yet the statistical properties of the tilt angle are not fully comprehended.
Shu-Guang Zeng, Ao-Yu Zhao, Shuang Yi, Sheng Zheng, Xiang-Yun Zeng, Lin-Hua Deng, Yao Huang   +6 more
doaj   +1 more source

Triggering multiple sclerosis at conception and early gestation: The variation in ultraviolet radiation is as important as its intensity. [PDF]

Heliyon, 2023
Davis GE, Davis MJ, Lowell WE.
europepmc   +1 more source

Backtracking Bipolar Magnetic Regions to Their Emergence: Two Groups and Their Implication in the Tilt Measurements

The Astrophysical Journal
Bipolar magnetic regions (BMRs) that appear on the solar photosphere are surface manifestations of the Sun’s internal magnetic field. With modern observations and continuous data streams, the study of BMRs has moved from manual sunspot catalogs to ...
Anu Sreedevi, Bidya Binay Karak, Bibhuti Kumar Jha, Rambahadur Gupta, Dipankar Banerjee   +4 more
doaj   +1 more source

About the Possible Solar Nature of the ~200 yr (de Vries/Suess) and ~2000–2500 yr (Hallstadt) Cycles and Their Influences on the Earth’s Climate: The Role of Solar-Triggered Tectonic Processes in General “Sun–Climate” Relationship

Atmosphere
(1) Introduction: The subject of the present study concerns the analysis of the existence and long time evolution of the solar ~200 yr (de Vries/Suess) and ~2400 yr (Hallstadt) cycles during the recent part of the Wurm ice epoch and the Holocene, as well
Boris Komitov
doaj   +1 more source

Multilayer Perceptron Network Optimization for Chaotic Time Series Modeling. [PDF]

Entropy (Basel), 2023
Qiao M, Liang Y, Tavares A, Shi X.
europepmc   +1 more source

Discovery of PHB1 as a Novel Candidate Gene in Dominant Optic Atrophy

Clinical Genetics, EarlyView.
A heterozygous PHB1 missense variant (p.Ser147Phe) segregates with autosomal dominant optic atrophy in a multi‐generation family. Structural and cellular analyses suggest altered mitochondrial dynamics, identifying PHB1 as a novel candidate gene for hereditary optic neuropathy. ABSTRACT Hereditary optic neuropathies comprise a genetically heterogeneous
Marija Volk, Aleš Maver, Martina Jarc Vidmar, Nuša Trošt, Tanja Višnjar, Ana Fakin, Lea Kovač, Maja Šuštar Habjan, Lucija Malinar, Sanja Petrović Pajić, Urška Dragin Jerman, Rok Romih, Marko Hawlina, Borut Peterlin   +13 more
wiley   +1 more source

The Making of Delta Sunspots

The Astrophysical Journal
We explore what fraction of delta sunspots with a sharp polarity inversion line (PIL) in photospheric magnetograms are produced by a writhe kink in an emerging twisted flux rope.
Ronald L. Moore, Sanjiv K. Tiwari, V. Aparna, Navdeep K. Panesar, Alphonse C. Sterling   +4 more
doaj   +1 more source